Ebook: Neuronal-glial Cell Interrelationships: Report of the Dahlem Workshop on Neuronal-glial Cell Interrelationships: Ontogeny, Maintenance, Injury, Repair, Berlin 1980, November 30 – December 5

need for an interdisciplinary approach to research, although scientifically desirable and laudable, is not easily met by the individual investigator, a statement which I must now qualify lest it be taken as a faint-hearted view of the problems which confront us in this or any other field of disease-orientated re­ search. In recent years the growth and scope of MS research parallels, in fact reflects, that which has occurred more generally concern­ ing research at all levels of complexity into the nature and modes of operation of the nervous systems of different animals. With respect to these developments Cowan (2) has observed that "this has led to the gradual emergence of a new, interdisciplinary ap­ proach to the study of the nervous system which has come to be known as Neuroscience. " At the center of neuroscience stands man striving to comprehend hirnself, not only in terms of the nuts and bolts of his own ner­ vous system and that of lower animals, but perhaps preoccupied most of all with the higher level nervous functions of perception, volition, cognition, and mentation, which characterize his "self. " The investigation of these processes depends ultimately on re­ search on man hirnself and the analysis of these processes in depth often must wait on Nature's own experiments to provide, through disease, the chance anatomical or biochemical lesions which dissect human behavior and expose the residual functions for scientific study.

---

---

Content:
Front Matter....Pages i-x
Stephen W. Kuffler (1913–1980)....Pages 1-4
Introduction....Pages 5-10
Clinical Problems of Multiple Sclerosis....Pages 11-24
The Role of Neuronal-Glial Cell Interaction During Brain Development....Pages 25-38
Membrane Specializations in Neuroglial Cells and at Neuron-Glia Contacts....Pages 39-56
Developmental Disorders of Myelination in Mouse Mutants....Pages 57-75
The Development of Electrical Excitability....Pages 77-91
Group on Ontogeny....Pages 92-92
Ontogeny State of the Art Report....Pages 93-114
Cellular and Non-Cellular Influences on Myelin-Forming Cells....Pages 115-130
Cell Interactions and the Cytoskeleton....Pages 131-145
Signalling Between Neuronal and Glial Cells....Pages 147-157
Aspects of Receptor Systems Possibly Relevant to Neuron-Glial Interactions and Multiple Sclerosis....Pages 159-167
Group on Maintenance....Pages 168-168
Maintenance State of the Art Report....Pages 169-202
Mechanisms of Tissue Damage in the Nervous System....Pages 203-215
Mechanism of Viral Injury to the Nervous System....Pages 217-228
Mechanisms of Cell Injury by Certain Protein Toxins....Pages 229-249
Distribution and Functional Significance of Sodium and Potassium Channels in Normal and Acutely Demyelinated Mammalian Myelinated Nerve....Pages 251-269
Group in Injury....Pages 270-270
Injury....Pages 271-286
Recovery and Function After Demyelination....Pages 287-301
Chemical Factors Influencing Neuronal Development....Pages 303-320
Developmental Expression of Antigenic Markers in Glial Subclasses....Pages 321-336
Group on Repair....Pages 338-338
Repair....Pages 339-361
Back Matter....Pages 363-378

---

Content:
Front Matter....Pages i-x
Stephen W. Kuffler (1913–1980)....Pages 1-4
Introduction....Pages 5-10
Clinical Problems of Multiple Sclerosis....Pages 11-24
The Role of Neuronal-Glial Cell Interaction During Brain Development....Pages 25-38
Membrane Specializations in Neuroglial Cells and at Neuron-Glia Contacts....Pages 39-56
Developmental Disorders of Myelination in Mouse Mutants....Pages 57-75
The Development of Electrical Excitability....Pages 77-91
Group on Ontogeny....Pages 92-92
Ontogeny State of the Art Report....Pages 93-114
Cellular and Non-Cellular Influences on Myelin-Forming Cells....Pages 115-130
Cell Interactions and the Cytoskeleton....Pages 131-145
Signalling Between Neuronal and Glial Cells....Pages 147-157
Aspects of Receptor Systems Possibly Relevant to Neuron-Glial Interactions and Multiple Sclerosis....Pages 159-167
Group on Maintenance....Pages 168-168
Maintenance State of the Art Report....Pages 169-202
Mechanisms of Tissue Damage in the Nervous System....Pages 203-215
Mechanism of Viral Injury to the Nervous System....Pages 217-228
Mechanisms of Cell Injury by Certain Protein Toxins....Pages 229-249
Distribution and Functional Significance of Sodium and Potassium Channels in Normal and Acutely Demyelinated Mammalian Myelinated Nerve....Pages 251-269
Group in Injury....Pages 270-270
Injury....Pages 271-286
Recovery and Function After Demyelination....Pages 287-301
Chemical Factors Influencing Neuronal Development....Pages 303-320
Developmental Expression of Antigenic Markers in Glial Subclasses....Pages 321-336
Group on Repair....Pages 338-338
Repair....Pages 339-361
Back Matter....Pages 363-378
....