Ebook: Biological Mineralization and Demineralization: Report of the Dahlem Workshop on Biological Mineralization and Demineralization Berlin 1981, October 18–23
- Tags: Cell Biology
- Series: Dahlem Workshop Reports 23
- Year: 1982
- Publisher: Springer-Verlag Berlin Heidelberg
- Edition: 1
- Language: English
- pdf
normal and pathological mineralization in vertebrates but also with the interesting problems involved in the formation of in tracellular deposits of calcium oxalate in plants. Here cal cium carbonate and silica may also be involved in the mineral ization processes. Calcium carbonate is an important component in the formation of mollusc and avian shells. The observation that both calcite and aragonite may be formed in biogenic cal cium carbonate raises important questions as to what factors control the formation of the final mineral phase. There is little doubt that thermodynamically less stable phases may be kinetically stabilized for long periods of time by other mole cules present in vivo. In normal mineralization, calcium salts may initially be deposited both within the cells and extracel lularly. In the latter case, the role of matrix vesicles and the ways in which the matrix components might control mineral ization were especially emphasized. There is clearly a need for more structural and functional information involving cells, matrix components, and their associated crystals. The develop ment of further techniques involving mutants, chromofluors, and fixatives for preservation of tissue and the ions present in vivo was recommended. In dealing with abnormal and pathological mineralization, the Workshop concentrated on urolithiasis, gout and pseudo-gout, and the formation of dental caries. Discussions based on the influence of media of low pH on mineral surfaces highlighted some of the factors of importance in controlling crystal dis solution.
Content:
Front Matter....Pages i-viii
Introduction....Pages 1-4
The Solubility Concept....Pages 5-21
Nucleation....Pages 23-35
The Mechanisms of Chrystal Growth and Dissolution....Pages 37-77
Phase Tranformation During Precipitation of Calcium Salts....Pages 79-99
Structures of Biological Minerals....Pages 101-141
Structural Properties of Cells Related to Tissue Mineralization....Pages 143-160
Structure of the Organic Matrix: Collagen Structure (Chemical)....Pages 161-177
Components of the Organic Matrix: Proteoglycans....Pages 179-198
Three Systems of Biomineralization in Plants with Comments on the Associated Organic Matrix....Pages 199-218
Structure of the Organic Matrix in Mollusc Shells and Avian Eggshells....Pages 219-232
Mechanisms of Normal Mineralization in Bone and Cartilage....Pages 233-241
Mechanisms of Normal Biological Mineralization of Calcium Carbonates....Pages 243-257
Abnormal Mineralization....Pages 259-270
Pathologic Mineralization, Nucleation, Growth, and Retention....Pages 271-285
Mechanisms and Regulation of Normal and Pathologic Demineralization....Pages 287-301
Mechanism of Dental Caries....Pages 303-326
Structure, Properties, and Function of Mineralized Tissue Components Group Report....Pages 327-350
Mechanisms of Mineralization (Normal) Group Report....Pages 351-363
Mechanisms of Pathological Mineralization Group Report....Pages 367-385
Back Matter....Pages 399-415
Mechanisms of Normal and Pathological Demineralization Group Report....Pages 389-398
Content:
Front Matter....Pages i-viii
Introduction....Pages 1-4
The Solubility Concept....Pages 5-21
Nucleation....Pages 23-35
The Mechanisms of Chrystal Growth and Dissolution....Pages 37-77
Phase Tranformation During Precipitation of Calcium Salts....Pages 79-99
Structures of Biological Minerals....Pages 101-141
Structural Properties of Cells Related to Tissue Mineralization....Pages 143-160
Structure of the Organic Matrix: Collagen Structure (Chemical)....Pages 161-177
Components of the Organic Matrix: Proteoglycans....Pages 179-198
Three Systems of Biomineralization in Plants with Comments on the Associated Organic Matrix....Pages 199-218
Structure of the Organic Matrix in Mollusc Shells and Avian Eggshells....Pages 219-232
Mechanisms of Normal Mineralization in Bone and Cartilage....Pages 233-241
Mechanisms of Normal Biological Mineralization of Calcium Carbonates....Pages 243-257
Abnormal Mineralization....Pages 259-270
Pathologic Mineralization, Nucleation, Growth, and Retention....Pages 271-285
Mechanisms and Regulation of Normal and Pathologic Demineralization....Pages 287-301
Mechanism of Dental Caries....Pages 303-326
Structure, Properties, and Function of Mineralized Tissue Components Group Report....Pages 327-350
Mechanisms of Mineralization (Normal) Group Report....Pages 351-363
Mechanisms of Pathological Mineralization Group Report....Pages 367-385
Back Matter....Pages 399-415
Mechanisms of Normal and Pathological Demineralization Group Report....Pages 389-398
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