Ebook: Gene-Enzyme Systems in Drosophila
- Tags: Cell Biology
- Series: Results and Problems in Cell Differentiation 6
- Year: 1975
- Publisher: Springer-Verlag Berlin Heidelberg
- Edition: 1
- Language: English
- pdf
There was a period in the history of modern biology when proteins were thought to be "gene products" in a rather direct sense. An account of their appearance and disappearance in the course of development and differentiation thus seemed an appropriate means of describing "gene regulation". When RNA was found to be the immediate product of genetic activity, the study of proteins as gene products lost some of its original attraction. Indeed, the development of the powerful method of nucleic acid hybridization aroused the hope that a large array of specific messenger-RNA molecules synthesized during cell differentiation could be individually assayed. The difficulties in the way of such ambitious projects were described in Volume 3 of this series: Nucleic Acid Hybridization in the Study of Cell Differentiation (ed. H. URSPRUNG, 1972). Enzymes are in large measure responsible for cell function. Clearly, their synthesis must be under genetic control. We are convinced that the study of enzyme behavior during development merits much attention, particularly if the work is carried out on a eukaryote that lends itself to genetic and developmental analysis. An impressive amount of genetic information is available on the insect Drosophila, and much has been learnt about its development. The giant chromosomes present in several tissues of this insect might well be useful in a continuing analysis of the appearance of specific enzymes and the transcription of the cognate genetic loci.
Content:
Front Matter....Pages I-XI
The Study of Gene-Enzyme Systems....Pages 1-31
Eye Color Mutants and Their Enzymes....Pages 32-48
Xanthine Dehydrogenase and Related Enzymes....Pages 49-69
Dehydrogenases....Pages 70-96
Enzymes of Tyrosine Metabolism....Pages 97-106
Amylase (?-1,4-glucan-4-glucanohydrolase, EC 3.2.1.1)....Pages 107-113
Non-Specific Hydrolytic Enzymes....Pages 114-129
Miscellaneous Enzymes....Pages 130-145
Back Matter....Pages 146-166
Content:
Front Matter....Pages I-XI
The Study of Gene-Enzyme Systems....Pages 1-31
Eye Color Mutants and Their Enzymes....Pages 32-48
Xanthine Dehydrogenase and Related Enzymes....Pages 49-69
Dehydrogenases....Pages 70-96
Enzymes of Tyrosine Metabolism....Pages 97-106
Amylase (?-1,4-glucan-4-glucanohydrolase, EC 3.2.1.1)....Pages 107-113
Non-Specific Hydrolytic Enzymes....Pages 114-129
Miscellaneous Enzymes....Pages 130-145
Back Matter....Pages 146-166
....