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The contributions to this volume were presented at a Symposium entitled "Current Topics in Muscle and Nonmuscle Motility" held in Dallas 19-21 November 1980 under the auspices of the A. Webb Roberts Center for Con­ tinuing Education, Baylor University Medical Center Dallas, and the Univer­ sity of Texas Health Science Center at Dallas. This very useful opportunity for a group of active investigators in motility to meet and discuss their latest findings was made possible in part by the income from an endowment fund established by a generous gift from Dr. Albert P. D'Errico in the Baylor University Medical Center. Dr. D'Errico was the first formally-trained neurosurgeon to practice in the Dallas area, the first Chief of Neurological Surgery, and a member of the Medical Board of the Baylor University Medi­ cal Center Dallas (1947 -1964). The income from this fund is used to promote the dissemination of up-to-date information in the Neurosciences, to provide intellectual stimulation, to add to the fund of knowledge, and improve the skills of neurosurgeons, neurologists, internists, and others in specialized fields of medicine. We are all indebted for this generous gift that made this enriching educational experience possible. We are also grateful for support the Symposium received from Electron Microscopy Sciences, Forma Scien­ tific, J. E. O. L. USA, Inc. , Ladd Research Industries, M. J. O. Diatome Co. , Or­ ganon Co. , Upjohn Co. , G. D. Searle & Co. , and Smith, Kline and French. Robert M.








Content:
Front Matter....Pages i-xvii
Actin Organization as an in Vitro Assay for Tumorigenicity....Pages 1-13
The Mechanism of Actin-Filament Assembly and Cross-Linking....Pages 15-44
A Scanning and Transmission Electron Microscope Examination of ACTH-Induced ‘Rounding up’ in Triton X-100 Cytoskeleton Residues of Cultured Adrenal Cells....Pages 45-52
The Role of Tubulin in Steroidogenesis of Mouse Adrenal Y-1 Cells and Rat Leydig CCL 43 Cells....Pages 53-61
Use of Monoclonal Antibodies to Study Cytoskeleton....Pages 63-71
Interaction of Calcium-Calmodulin in Microtubule Assembly in Vitro....Pages 73-84
Microtubules in Adult Mammalian Muscle....Pages 85-92
Microtubules and Heart-Cell Contraction....Pages 93-101
The Association of Creatine Phosphokinase with the Mitotic Spindle....Pages 103-119
Cytoskeletal Defects in Avian Muscular Dystrophy....Pages 121-140
The Structure of Vertebrate Skeletal-Muscle Myosin Filaments....Pages 141-171
Cross-Bridge Movement and the Conformational State of the Myosin Hinge in Skeletal Muscle....Pages 173-175
The Regulation of Myosin-Light-Chain Synthesis in Heterokaryons between Differentiated and Undifferentiated Myogenic Cells....Pages 177-184
Phosphorylation of Myosin and the Regulation of Smooth-Muscle Actomyosin....Pages 185-220
Three-Dimensional Structure of Muscle Membranes Involved in the Regulation of Contraction in Skeletal-Muscle Fibers....Pages 221-230
Mechanism of the Apparent Inhibitory Effect of Mg2+ and Ca2+ on the Actomyosin MgATPase in Relation to the L2 Light Chain....Pages 231-237
Actin Activation of Phosphorylated Aortic Myosin....Pages 239-243
The Regulation of Cardiac-Muscle Contraction by Troponin....Pages 245-255
Fluorescent-Probe Studies of Contractile Proteins....Pages 257-278
Myosin Flexibility....Pages 279-302
Back Matter....Pages 303-310



Content:
Front Matter....Pages i-xvii
Actin Organization as an in Vitro Assay for Tumorigenicity....Pages 1-13
The Mechanism of Actin-Filament Assembly and Cross-Linking....Pages 15-44
A Scanning and Transmission Electron Microscope Examination of ACTH-Induced ‘Rounding up’ in Triton X-100 Cytoskeleton Residues of Cultured Adrenal Cells....Pages 45-52
The Role of Tubulin in Steroidogenesis of Mouse Adrenal Y-1 Cells and Rat Leydig CCL 43 Cells....Pages 53-61
Use of Monoclonal Antibodies to Study Cytoskeleton....Pages 63-71
Interaction of Calcium-Calmodulin in Microtubule Assembly in Vitro....Pages 73-84
Microtubules in Adult Mammalian Muscle....Pages 85-92
Microtubules and Heart-Cell Contraction....Pages 93-101
The Association of Creatine Phosphokinase with the Mitotic Spindle....Pages 103-119
Cytoskeletal Defects in Avian Muscular Dystrophy....Pages 121-140
The Structure of Vertebrate Skeletal-Muscle Myosin Filaments....Pages 141-171
Cross-Bridge Movement and the Conformational State of the Myosin Hinge in Skeletal Muscle....Pages 173-175
The Regulation of Myosin-Light-Chain Synthesis in Heterokaryons between Differentiated and Undifferentiated Myogenic Cells....Pages 177-184
Phosphorylation of Myosin and the Regulation of Smooth-Muscle Actomyosin....Pages 185-220
Three-Dimensional Structure of Muscle Membranes Involved in the Regulation of Contraction in Skeletal-Muscle Fibers....Pages 221-230
Mechanism of the Apparent Inhibitory Effect of Mg2+ and Ca2+ on the Actomyosin MgATPase in Relation to the L2 Light Chain....Pages 231-237
Actin Activation of Phosphorylated Aortic Myosin....Pages 239-243
The Regulation of Cardiac-Muscle Contraction by Troponin....Pages 245-255
Fluorescent-Probe Studies of Contractile Proteins....Pages 257-278
Myosin Flexibility....Pages 279-302
Back Matter....Pages 303-310
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