Ebook: Principles of Protein X-ray Crystallography

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Content:
Front Matter....Pages i-xiii
Crystallizing a Protein....Pages 1-18
X-ray Sources and Detectors....Pages 19-53
Crystals....Pages 54-73
The Theory of X-ray Diffraction by a Crystal....Pages 74-116
Average Reflection Intensity and Distribution of Structure Factor Data....Pages 117-124
Special Forms of the Structure Factor....Pages 125-128
The Solution of the Phase Problem by the Isomorphous Replacement Method....Pages 129-182
Phase Improvement....Pages 183-198
Anomalous Scattering in the Determination of the Protein Phase Angles and the Absolute Configuration....Pages 199-210
Molecular Replacement....Pages 211-230
Direct Methods....Pages 231-233
Laue Diffraction....Pages 234-241
Refinement of the Model Structure....Pages 242-263
The Combination of Phase Information....Pages 264-269
Checking for Gross Errors and Estimating the Accuracy of the Structural Model....Pages 270-281
Back Matter....Pages 282-305

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Content:
Front Matter....Pages i-xiii
Crystallizing a Protein....Pages 1-18
X-ray Sources and Detectors....Pages 19-53
Crystals....Pages 54-73
The Theory of X-ray Diffraction by a Crystal....Pages 74-116
Average Reflection Intensity and Distribution of Structure Factor Data....Pages 117-124
Special Forms of the Structure Factor....Pages 125-128
The Solution of the Phase Problem by the Isomorphous Replacement Method....Pages 129-182
Phase Improvement....Pages 183-198
Anomalous Scattering in the Determination of the Protein Phase Angles and the Absolute Configuration....Pages 199-210
Molecular Replacement....Pages 211-230
Direct Methods....Pages 231-233
Laue Diffraction....Pages 234-241
Refinement of the Model Structure....Pages 242-263
The Combination of Phase Information....Pages 264-269
Checking for Gross Errors and Estimating the Accuracy of the Structural Model....Pages 270-281
Back Matter....Pages 282-305
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