Ebook: Biophysics of the Cell Surface

It is common practice to publish conference papers in books or monograph series. This gives some advantage to those who did not have the opportunity to attend the meetings, but it irritates and disappoints others who may have hoped for a set of closely related reviews. With this book we have tried to find a compromise. It presents a selection from the topics which have been discussed in a series of inter­ national symposia entitled "Biophysics of Cell Surface", held in 1976, 1978, 1981, 1985 and 1988 in the GDR, and subsequently published in the journal STUDIA BIOPHYSICA (volumes 56, 74, 90, 110, 1271. Nearly all the contributors to this book participated in one or more of the meetings. We hope that our choice of topics selected for this book manages to reflect the variety and interest of the broad range of subjects which fall within the scope of membrane biophysics, without taking on the randomness of a scientific car-boot sale. We would like to express our thanks to all colleagues and organ~ isations who helped to realize the conferences and particularly this book. financial support for the symposia of 1985 and 1988 was provided by the IUPAB. A number of topics, reflected in this book, resulted in internat­ ional cooperations, supported by various organisations. We are especially grateful for the support of UNESCO research project on biophysicS in this respect. The European Bureau (ROSTE) of UNESCO supported the editorial work of this book.

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This volume concentrates attention on the role of membranes in regulating cellular processes, as well as on the interactions of cells with their environment - a large field with a great number of applications. To make this task manageable the field is narrowed by introducing the word "biophysics" into the title. Starting with the molecular aspects of the dynamic structure of the membrane, chapters treating phenomenological aspects of membrane electrostatics, interfacial stability and membrane elastic energy are presented. In a third part functional aspects are discussed: The role of membrane electric field, membrane fusion, membrane lysis, membrane interactions, membrane adhesion and membrane motion.

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This volume concentrates attention on the role of membranes in regulating cellular processes, as well as on the interactions of cells with their environment - a large field with a great number of applications. To make this task manageable the field is narrowed by introducing the word "biophysics" into the title. Starting with the molecular aspects of the dynamic structure of the membrane, chapters treating phenomenological aspects of membrane electrostatics, interfacial stability and membrane elastic energy are presented. In a third part functional aspects are discussed: The role of membrane electric field, membrane fusion, membrane lysis, membrane interactions, membrane adhesion and membrane motion.
Content:
Front Matter....Pages I-VIII
Introduction....Pages 1-2
Translocation and distribution of phospholipids across eukaryotic plasma membranes....Pages 3-22
Protein-lipid interactions at membrane surfaces....Pages 23-50
The super-ordered fluid: A domain model of cell surface membranes....Pages 51-59
Membrane hydration....Pages 61-73
Cell surface electrostatics and electrokinetics....Pages 75-108
Interfacial stability....Pages 109-130
Surface free energy contribution to cell interactions....Pages 131-152
General thermodynamic description of elastic properties of membranes....Pages 153-172
The influence of membrane electric field on cellular functions....Pages 173-192
Phospholipid vesicle fusion induced by cations and poly-(ethylene glycol)....Pages 193-219
Membrane fusion and lysis by the amphiphilic peptides induced by charge neutralization: A model study of virus membrane fusion mechanism....Pages 221-236
Significance of hydrophobic interactions in membrane fusion of enveloped viruses....Pages 237-261
Cell contact with solid surfaces....Pages 263-285
Cell-cell contacts....Pages 287-321
Membrane-cytoskeletal interactions in cell adhesion and locomotion....Pages 323-339
The behavior of cell surface components during cell locomotion: A quantitative approach....Pages 341-361
Back Matter....Pages 363-366

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This volume concentrates attention on the role of membranes in regulating cellular processes, as well as on the interactions of cells with their environment - a large field with a great number of applications. To make this task manageable the field is narrowed by introducing the word "biophysics" into the title. Starting with the molecular aspects of the dynamic structure of the membrane, chapters treating phenomenological aspects of membrane electrostatics, interfacial stability and membrane elastic energy are presented. In a third part functional aspects are discussed: The role of membrane electric field, membrane fusion, membrane lysis, membrane interactions, membrane adhesion and membrane motion.
Content:
Front Matter....Pages I-VIII
Introduction....Pages 1-2
Translocation and distribution of phospholipids across eukaryotic plasma membranes....Pages 3-22
Protein-lipid interactions at membrane surfaces....Pages 23-50
The super-ordered fluid: A domain model of cell surface membranes....Pages 51-59
Membrane hydration....Pages 61-73
Cell surface electrostatics and electrokinetics....Pages 75-108
Interfacial stability....Pages 109-130
Surface free energy contribution to cell interactions....Pages 131-152
General thermodynamic description of elastic properties of membranes....Pages 153-172
The influence of membrane electric field on cellular functions....Pages 173-192
Phospholipid vesicle fusion induced by cations and poly-(ethylene glycol)....Pages 193-219
Membrane fusion and lysis by the amphiphilic peptides induced by charge neutralization: A model study of virus membrane fusion mechanism....Pages 221-236
Significance of hydrophobic interactions in membrane fusion of enveloped viruses....Pages 237-261
Cell contact with solid surfaces....Pages 263-285
Cell-cell contacts....Pages 287-321
Membrane-cytoskeletal interactions in cell adhesion and locomotion....Pages 323-339
The behavior of cell surface components during cell locomotion: A quantitative approach....Pages 341-361
Back Matter....Pages 363-366
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