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Ebook: Ventricular/Vascular Coupling: Clinical, Physiological, and Engineering Aspects

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27.01.2024
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Physiologists have long been interested in the interaction, or coupling, between the heart and the vasculature. The early literature consists mainly of phenomenological descriptions of cardiac alterations resulting from specific interventions in the vasculature. Hundreds of studies, for example, describe functional aspects of hypertrophied myocardium associated with the excessive vascular loading produced by various types of experimental hypertension. Recently, the concepts of ventricular/vascular interaction have found important clinical application. The widespread use of vaso­ dilators and of intraaortic counterpUlsation balloons for unloading an ov­ erburdened, diseased heart is a prime example. Despite the interest in this field, until as recently as 20 years ago we were not able to describe ventricular or vascular function in a framework suitable for quantitatively expressing the interaction between these two complex systems. Three major developments-description of ventricular function in terms of both the time-varying elastance and the pump function graph and quantification of vascular function in terms of impedance­ have changed this. These functional descriptions now enable systems en­ gineers, bioengineers, physiologists, and clinicians to address very specific quantitative aspects of ventricular/vascular interaction and have resulted in a flurry of papers and symposia devoted to this subject.








Content:
Front Matter....Pages i-xii
Left Ventricular-Systemic Arterial Coupling in Humans and Strategies to Improve Coupling in Disease States....Pages 1-19
Influence of the Venous System on Ventricular/Arterial Coupling....Pages 20-41
The Pathophysiology of Pulmonary Vascular Disease Associated with Congenital Cardiac Lesions....Pages 42-78
Age-Related Changes in Left Ventricular/Arterial Coupling....Pages 79-114
Aging and Vascular Impedance....Pages 115-139
Arterial Reflections and Pressure Waveforms in Humans....Pages 140-158
The Control of Cardiac Output Through Coupling of Heart and Blood Vessels....Pages 159-179
Matching between Right Ventricle and Pulmonary Bed....Pages 180-202
Heart-Arterial Coupling: How to Bypass the Aortic Valves....Pages 203-209
Ventricular Interaction with the Vascular System in Terms of Pressure-Volume Relationships....Pages 210-239
Left Ventricular Systolic Resistance and Its Role in Coupling the Ventricle to the Arterial Circulation....Pages 240-261
Influence of Extracardiac Forces on the Cardiopulmonary Unit....Pages 262-287
Sensitivity Analysis of Interaction between the Left Ventricle and the Systemic Arteries....Pages 288-300
Modeling of the Coupling of the Left Ventricle to the Peripheral Circulation....Pages 301-333
The Effects of Finite Wave Velocity and Discrete Reflections on Ventricular Loading....Pages 334-383
Estimation of Arterial Compliance....Pages 384-398
Back Matter....Pages 399-406



Content:
Front Matter....Pages i-xii
Left Ventricular-Systemic Arterial Coupling in Humans and Strategies to Improve Coupling in Disease States....Pages 1-19
Influence of the Venous System on Ventricular/Arterial Coupling....Pages 20-41
The Pathophysiology of Pulmonary Vascular Disease Associated with Congenital Cardiac Lesions....Pages 42-78
Age-Related Changes in Left Ventricular/Arterial Coupling....Pages 79-114
Aging and Vascular Impedance....Pages 115-139
Arterial Reflections and Pressure Waveforms in Humans....Pages 140-158
The Control of Cardiac Output Through Coupling of Heart and Blood Vessels....Pages 159-179
Matching between Right Ventricle and Pulmonary Bed....Pages 180-202
Heart-Arterial Coupling: How to Bypass the Aortic Valves....Pages 203-209
Ventricular Interaction with the Vascular System in Terms of Pressure-Volume Relationships....Pages 210-239
Left Ventricular Systolic Resistance and Its Role in Coupling the Ventricle to the Arterial Circulation....Pages 240-261
Influence of Extracardiac Forces on the Cardiopulmonary Unit....Pages 262-287
Sensitivity Analysis of Interaction between the Left Ventricle and the Systemic Arteries....Pages 288-300
Modeling of the Coupling of the Left Ventricle to the Peripheral Circulation....Pages 301-333
The Effects of Finite Wave Velocity and Discrete Reflections on Ventricular Loading....Pages 334-383
Estimation of Arterial Compliance....Pages 384-398
Back Matter....Pages 399-406
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