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Ebook: Vasopressin: Principles and Properties

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The concept for Vasopressin: Principles and Properties originated during the sum­ mer of 1983. From reviewing the rich and diverse literature on vasopressin, it became evident that the rapid advancements in this field made it difficult to syn­ thesize the information gathered from divergent scientific disciplines into a coherent view of the biological role of vasopressin. We perceived the need for a series of critical reviews delineating this recent progress. Over the past decade, major advances have been made in studies of the anatomy, physiology, phar­ macology, molecular biology, and behavioral activities of vasopressin. This is, in no small measure, due to the finding that vasopressin can no longer be regarded solely as a neurohypophysial hormone. Our present knowledge is that vasopressin is synthesized in also has an axonal messenger role in the nervous system and of the brain, although the functions of vasopressin in these periph­ sites outside of vasopressin eral sites are not well understood. In order to prepare an overview concentrating on recent studies in vertebrates, authors were selected based on their expertise and asked to review their research area, including the work from other laboratories. It was our intent to provide an updated definitive reference which would complement and extend such past texts as Neurohypophysial Hor­ mones and Similar Polypeptides (Handbook of Experimental Pharmacology, Vol­ ume XXIII, 1968) and The Pituitary Gland and Its Neuroendocrine Control (Handbook of Physiology, Section 7: Volume IV, 1974).








Content:
Front Matter....Pages i-xviii
Anatomy and Function of the Classic Vasopressin-Secreting Hypothalamus-Neurohypophysial System....Pages 1-89
Vasopressin Localization and Putative Functions in the Brain....Pages 91-115
Development of Vasopressin Systems and Their Functions....Pages 117-174
Biosynthesis of Vasopressin and Neurophysins....Pages 175-209
Electrophysiology of the Central Vasopressin System....Pages 211-256
Electrophysiological Actions of Vasopressin in Extrahypothalamic Regions of the Central Nervous System....Pages 257-274
Effect of Neurotransmitters and Neuropeptides on Vasopressin Release....Pages 275-333
Selective Agonists and Antagonists of Vasopressin....Pages 335-368
Physiological Effects of Vasopressin on the Kidney....Pages 369-387
Cardiovascular Actions of Vasopressin....Pages 389-433
Vasopressin and Endocrine Function....Pages 435-475
Vasopressin Receptors in the Brain and Pituitary....Pages 477-496
Metabolic Processing of Vasopressin in the Brain and Significance of Metabolites....Pages 497-516
Vasopressin and Animal Behavior....Pages 517-547
Vasopressin and Human Behavior....Pages 549-578
Aging of Rodent Vasopressin Systems....Pages 579-610
Vasopressin in Relationship to Human Aging and Dementia....Pages 611-625
Back Matter....Pages 627-635



Content:
Front Matter....Pages i-xviii
Anatomy and Function of the Classic Vasopressin-Secreting Hypothalamus-Neurohypophysial System....Pages 1-89
Vasopressin Localization and Putative Functions in the Brain....Pages 91-115
Development of Vasopressin Systems and Their Functions....Pages 117-174
Biosynthesis of Vasopressin and Neurophysins....Pages 175-209
Electrophysiology of the Central Vasopressin System....Pages 211-256
Electrophysiological Actions of Vasopressin in Extrahypothalamic Regions of the Central Nervous System....Pages 257-274
Effect of Neurotransmitters and Neuropeptides on Vasopressin Release....Pages 275-333
Selective Agonists and Antagonists of Vasopressin....Pages 335-368
Physiological Effects of Vasopressin on the Kidney....Pages 369-387
Cardiovascular Actions of Vasopressin....Pages 389-433
Vasopressin and Endocrine Function....Pages 435-475
Vasopressin Receptors in the Brain and Pituitary....Pages 477-496
Metabolic Processing of Vasopressin in the Brain and Significance of Metabolites....Pages 497-516
Vasopressin and Animal Behavior....Pages 517-547
Vasopressin and Human Behavior....Pages 549-578
Aging of Rodent Vasopressin Systems....Pages 579-610
Vasopressin in Relationship to Human Aging and Dementia....Pages 611-625
Back Matter....Pages 627-635
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