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Rhythms of the heart and of the nervous and endocrine system, breathing, locomotory movements, sleep, circadian rhythms and tissue cell cycles are major elements of the temporal order of man. The dynamics of these systems are characterized by changes in the properties of an oscillator, transitions from oscillatory states into chaotic or stationary states, and vice versa, coupling or uncoupling between two or more oscillators. Any deviation from the normal range to either more or less ordered states may be defined as temporal disorder. Pathological changes of temporal organization, such as tremor, epileptic seizures, Cheyne-Stokes breathing, cardiac arrhythmicities and circadian desynchronization, may be caused by small changes in the order (control) parameters. One major aspect of the symposium was the analysis of characteristic features of these temporal control systems, including nonlinear dynamics of interactions, positive, negative and mixed feedback systems, temporal delays, and their mathematical description and modelling. The ultimate goal is a better understanding of the principles of temporal organization in order to treat periodic diseases or other perturbations of "normal" dynamics in human oscillatory systems.




Rhythms of the heart and of the nervous and endocrine system, breathing, locomotory movements, sleep, circadian rhythms and tissue cell cycles are major elements of the temporal order of man. The dynamics of these systems are characterized by changes in the properties of an oscillator, transitions from oscillatory states into chaotic or stationary states, and vice versa, coupling or uncoupling between two or more oscillators. Any deviation from the normal range to either more or less ordered states may be defined as temporal disorder. Pathological changes of temporal organization, such as tremor, epileptic seizures, Cheyne-Stokes breathing, cardiac arrhythmicities and circadian desynchronization, may be caused by small changes in the order (control) parameters. One major aspect of the symposium was the analysis of characteristic features of these temporal control systems, including nonlinear dynamics of interactions, positive, negative and mixed feedback systems, temporal delays, and their mathematical description and modelling. The ultimate goal is a better understanding of the principles of temporal organization in order to treat periodic diseases or other perturbations of "normal" dynamics in human oscillatory systems.


Rhythms of the heart and of the nervous and endocrine system, breathing, locomotory movements, sleep, circadian rhythms and tissue cell cycles are major elements of the temporal order of man. The dynamics of these systems are characterized by changes in the properties of an oscillator, transitions from oscillatory states into chaotic or stationary states, and vice versa, coupling or uncoupling between two or more oscillators. Any deviation from the normal range to either more or less ordered states may be defined as temporal disorder. Pathological changes of temporal organization, such as tremor, epileptic seizures, Cheyne-Stokes breathing, cardiac arrhythmicities and circadian desynchronization, may be caused by small changes in the order (control) parameters. One major aspect of the symposium was the analysis of characteristic features of these temporal control systems, including nonlinear dynamics of interactions, positive, negative and mixed feedback systems, temporal delays, and their mathematical description and modelling. The ultimate goal is a better understanding of the principles of temporal organization in order to treat periodic diseases or other perturbations of "normal" dynamics in human oscillatory systems.
Content:
Front Matter....Pages I-IX
Temporal Disorder-Introductory Remarks....Pages 1-5
Front Matter....Pages 7-7
Coupled Oscillators in Health and Disease....Pages 8-14
Periodic Signaling and Receptor Desensitization: From cAMP Oscillations in Dictyostelium Cells to Pulsatile Patterns of Hormone Secretion....Pages 15-23
Oscillations and the Regulation of Spatial Order in Developing Systems....Pages 24-29
Mixed Feedback: A Paradigm for Regular and Irregular Oscillations....Pages 30-46
Front Matter....Pages 47-47
Strange Attractors in the Human Cortex....Pages 48-56
Analysis of the Human Electroencephalogram with Methods from Nonlinear Dynamics....Pages 57-68
Studying Temporal Order in Human CNS by Means of “Running” Frequency and Coherence Analysis....Pages 69-78
Central Rhythmicities in Motor Control and Its Perturbances....Pages 79-82
Neurological Oscillations: Formulation of Mathematical Control Models and Applications to Clinical Syndromes....Pages 83-101
Quantitative Theory of Changes in Oscillatory Hand Movements — Application of Methods of Synergetics....Pages 102-109
Investigation of Agonistic/Antagonistic Movement in Parkinson’s Disease from an Ergodic Point of View....Pages 110-115
Front Matter....Pages 117-117
Nonlinear Dynamics, Fractals, Cardiac Physiology and Sudden Death....Pages 118-125
Afterpotentials and Pacemaker Oscillations in an Ionic Model of Cardiac Purkinje Fibres....Pages 126-133
Causes of Propagation Failure in Excitable Media....Pages 134-140
Ultradian Oscillations in Human Blood Pressure: Effects of Age....Pages 141-149
New Aspects of the Dynamics of Acute Myocardial Infarction....Pages 150-151
Coordination in the Circulatory and Respiratory Systems....Pages 152-158
Front Matter....Pages 159-159
The Autonomous Time Structure and Its Reactive Modifications in the Human Organism....Pages 160-175
Bright Light in Work-Sleep Schedules for Shift Workers: Application of Circadian Rhythm Principles....Pages 176-185
Front Matter....Pages 159-159
Disturbances of the Circadian System Due to Masking Effects....Pages 186-188
Simulation of the Circadian Response to Time Zone Transitions by a Van der Pol Oscillator....Pages 189-193
Circadian Rhythms and Depression....Pages 194-201
Lithium Effects on Circadian Rhythms....Pages 202-209
Treatment of Chronobiologic Sleep and Mood Disorders with Light: Theory and Practice....Pages 210-218
Free-Running Melatonin Rhythms in Blind People: Phase Shifts with Melatonin and Triazolam Administration....Pages 219-224
Effects of Pacemaker Lesions on the Temporal Organization in Mammals....Pages 225-232
Perturbations of Cellular Circadian Rhythms by Light and Temperature....Pages 233-245
Front Matter....Pages 247-247
Temporal Order and Disorder in a Model That Regulates Ovulation Number....Pages 248-257
Back Matter....Pages 259-259


Rhythms of the heart and of the nervous and endocrine system, breathing, locomotory movements, sleep, circadian rhythms and tissue cell cycles are major elements of the temporal order of man. The dynamics of these systems are characterized by changes in the properties of an oscillator, transitions from oscillatory states into chaotic or stationary states, and vice versa, coupling or uncoupling between two or more oscillators. Any deviation from the normal range to either more or less ordered states may be defined as temporal disorder. Pathological changes of temporal organization, such as tremor, epileptic seizures, Cheyne-Stokes breathing, cardiac arrhythmicities and circadian desynchronization, may be caused by small changes in the order (control) parameters. One major aspect of the symposium was the analysis of characteristic features of these temporal control systems, including nonlinear dynamics of interactions, positive, negative and mixed feedback systems, temporal delays, and their mathematical description and modelling. The ultimate goal is a better understanding of the principles of temporal organization in order to treat periodic diseases or other perturbations of "normal" dynamics in human oscillatory systems.
Content:
Front Matter....Pages I-IX
Temporal Disorder-Introductory Remarks....Pages 1-5
Front Matter....Pages 7-7
Coupled Oscillators in Health and Disease....Pages 8-14
Periodic Signaling and Receptor Desensitization: From cAMP Oscillations in Dictyostelium Cells to Pulsatile Patterns of Hormone Secretion....Pages 15-23
Oscillations and the Regulation of Spatial Order in Developing Systems....Pages 24-29
Mixed Feedback: A Paradigm for Regular and Irregular Oscillations....Pages 30-46
Front Matter....Pages 47-47
Strange Attractors in the Human Cortex....Pages 48-56
Analysis of the Human Electroencephalogram with Methods from Nonlinear Dynamics....Pages 57-68
Studying Temporal Order in Human CNS by Means of “Running” Frequency and Coherence Analysis....Pages 69-78
Central Rhythmicities in Motor Control and Its Perturbances....Pages 79-82
Neurological Oscillations: Formulation of Mathematical Control Models and Applications to Clinical Syndromes....Pages 83-101
Quantitative Theory of Changes in Oscillatory Hand Movements — Application of Methods of Synergetics....Pages 102-109
Investigation of Agonistic/Antagonistic Movement in Parkinson’s Disease from an Ergodic Point of View....Pages 110-115
Front Matter....Pages 117-117
Nonlinear Dynamics, Fractals, Cardiac Physiology and Sudden Death....Pages 118-125
Afterpotentials and Pacemaker Oscillations in an Ionic Model of Cardiac Purkinje Fibres....Pages 126-133
Causes of Propagation Failure in Excitable Media....Pages 134-140
Ultradian Oscillations in Human Blood Pressure: Effects of Age....Pages 141-149
New Aspects of the Dynamics of Acute Myocardial Infarction....Pages 150-151
Coordination in the Circulatory and Respiratory Systems....Pages 152-158
Front Matter....Pages 159-159
The Autonomous Time Structure and Its Reactive Modifications in the Human Organism....Pages 160-175
Bright Light in Work-Sleep Schedules for Shift Workers: Application of Circadian Rhythm Principles....Pages 176-185
Front Matter....Pages 159-159
Disturbances of the Circadian System Due to Masking Effects....Pages 186-188
Simulation of the Circadian Response to Time Zone Transitions by a Van der Pol Oscillator....Pages 189-193
Circadian Rhythms and Depression....Pages 194-201
Lithium Effects on Circadian Rhythms....Pages 202-209
Treatment of Chronobiologic Sleep and Mood Disorders with Light: Theory and Practice....Pages 210-218
Free-Running Melatonin Rhythms in Blind People: Phase Shifts with Melatonin and Triazolam Administration....Pages 219-224
Effects of Pacemaker Lesions on the Temporal Organization in Mammals....Pages 225-232
Perturbations of Cellular Circadian Rhythms by Light and Temperature....Pages 233-245
Front Matter....Pages 247-247
Temporal Order and Disorder in a Model That Regulates Ovulation Number....Pages 248-257
Back Matter....Pages 259-259
....
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