Ebook: Technical Advances in Biomedical Physics

This Advanced Study Institute was arranged to discuss in depth the physical and technical basis of the latest developments in methods of measurement and image analysis suitable for determining the prop­ erties of cells and tissues and for evaluating medical structures. All topics under consideration have benefitted dramatically from an injection of new ideas during the past 10 years, and some have developed even more recently. The Institute brought together lecturers and participants from 14 different countries, and the subject matter recorded in this volume may be considered under two general headings. The first part of the meeting concentrated on techniques that are most appropriate at the cellular level. One major area of develop­ ment has been centered on attempts to classify cells by computerized ex­ traction of visual features, and here, it was notable how different techniques frequently complement each other. This part of the meeting also examined mechanisms of damage at the cellular level caused by different forms of radiation, and the contrasting effects of ionizing radiation, ultraviolet light and ultrasound were highlighted.

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Content:
Front Matter....Pages I-XIV
Front Matter....Pages 1-1
New Physical Methods in Medicine and Environmental Sciences....Pages 3-21
Physics in Medicine and Biology — 10 Years of Progress....Pages 23-38
Clinicians’ Expectations from the New Technology for in Vivo Diagnostic Examinations....Pages 39-49
Recent Developments for in Vivo Diagnostic Examinations using Physical Methods — the Clinician’s Viewpoint....Pages 51-55
Front Matter....Pages 57-57
Cell Image Analysis in Quantitative Cytology....Pages 59-90
A Cell Biologist’s View of Current Technology — its Achievements and Limitations....Pages 91-97
Development of Optical Methods for Quantitative Cytochemistry....Pages 99-110
TV-Contrast Enhancement Methods for Chromosome Analysis....Pages 111-116
Luminescence and Fluorescence Methods....Pages 117-126
Microbeam Design Considerations....Pages 127-138
Partial Nuclear and Cytoplasmic (Mitochondtrial) Irradiation of Single Living Cells using Ultraviolet and Visible Light....Pages 139-145
Photobiology of Furocoumarins (Psoralens) and Recent Developments in the Photochemotherapy (PUVA) of Psoriasis....Pages 147-155
Effects of Ionizing Radiation on the Structure and Physical Properties of the Skin....Pages 157-173
Electromagnetic Field Dosimetry in Biomedical Investigations....Pages 175-184
Front Matter....Pages 185-185
Physical Principles of Radionuclide Emission Imaging using Single Photon Techniques....Pages 187-217
Physical Limitations to the Quality of X- and Gama Ray Images....Pages 219-234
The Presentation of Photon-Limited Images....Pages 235-258
The Influence of Digitisation on the Quality of Radionuclide Images....Pages 259-269
Diagnostic Processing and Analysis of Medical Images....Pages 271-286
The Principles and Practice of Radiopharmaceutical Production....Pages 287-318
Front Matter....Pages 185-185
Planning and Running a Hospital Radiopharmacy....Pages 319-330
New Advances in Nuclear Cardiology....Pages 331-335
Applications of Convolution and Deconvolution Methods in Nuclear Medicine....Pages 337-344
Some Recent Developments in X-Ray Techniques....Pages 345-368
Biomedical Applications of Ultrasound....Pages 369-375
Nuclear Magnetic Resonance Proton Imaging....Pages 377-410
Back Matter....Pages 411-418

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Content:
Front Matter....Pages I-XIV
Front Matter....Pages 1-1
New Physical Methods in Medicine and Environmental Sciences....Pages 3-21
Physics in Medicine and Biology — 10 Years of Progress....Pages 23-38
Clinicians’ Expectations from the New Technology for in Vivo Diagnostic Examinations....Pages 39-49
Recent Developments for in Vivo Diagnostic Examinations using Physical Methods — the Clinician’s Viewpoint....Pages 51-55
Front Matter....Pages 57-57
Cell Image Analysis in Quantitative Cytology....Pages 59-90
A Cell Biologist’s View of Current Technology — its Achievements and Limitations....Pages 91-97
Development of Optical Methods for Quantitative Cytochemistry....Pages 99-110
TV-Contrast Enhancement Methods for Chromosome Analysis....Pages 111-116
Luminescence and Fluorescence Methods....Pages 117-126
Microbeam Design Considerations....Pages 127-138
Partial Nuclear and Cytoplasmic (Mitochondtrial) Irradiation of Single Living Cells using Ultraviolet and Visible Light....Pages 139-145
Photobiology of Furocoumarins (Psoralens) and Recent Developments in the Photochemotherapy (PUVA) of Psoriasis....Pages 147-155
Effects of Ionizing Radiation on the Structure and Physical Properties of the Skin....Pages 157-173
Electromagnetic Field Dosimetry in Biomedical Investigations....Pages 175-184
Front Matter....Pages 185-185
Physical Principles of Radionuclide Emission Imaging using Single Photon Techniques....Pages 187-217
Physical Limitations to the Quality of X- and Gama Ray Images....Pages 219-234
The Presentation of Photon-Limited Images....Pages 235-258
The Influence of Digitisation on the Quality of Radionuclide Images....Pages 259-269
Diagnostic Processing and Analysis of Medical Images....Pages 271-286
The Principles and Practice of Radiopharmaceutical Production....Pages 287-318
Front Matter....Pages 185-185
Planning and Running a Hospital Radiopharmacy....Pages 319-330
New Advances in Nuclear Cardiology....Pages 331-335
Applications of Convolution and Deconvolution Methods in Nuclear Medicine....Pages 337-344
Some Recent Developments in X-Ray Techniques....Pages 345-368
Biomedical Applications of Ultrasound....Pages 369-375
Nuclear Magnetic Resonance Proton Imaging....Pages 377-410
Back Matter....Pages 411-418
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