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Ebook: Membrane Processes: Molecular Biology and Medical Applications

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27.01.2024
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The burgeoning interest in biomembranes in recent years has been such that "membranology" is now virtuMtyasubject in its own right, cutting vertically, as it were, through the strata of conventional disciplines from mathematics and physics, through chemistry, to biology. The very scope of the topic is thus so daunting that it is tempting to treat it only at one stratum of this hierarchy, be it the biophysics of phospholipid bilayers or the biochemistry of interactions at the cell surface. Such an approach is entirely valid, particularly among specialists with common interests. However, this approach does present a distorted perspective to the newcomer to the field, and, more significantly, it fails to stimulate cross fertil­ ization of ideas among workers at the various disciplinary levels. For example, as in all areas of molecular biology, the clinicians are frequently unaware of the contributions to their problems that might be made by the application of more basic knowledge and techniques. Conversely, biochemists or biophysicists may be ignorant of the existing practical problems to which they might address their expertise.








Content:
Front Matter....Pages i-x
Front Matter....Pages 1-1
Reconstituted Membrane Systems....Pages 3-26
Molecular Aspects of Membrane Fusion....Pages 27-48
Microheterogeneity in Biological Membranes....Pages 49-64
Molecular Composition and Functional Properties of Human Liver Mitochondria....Pages 65-91
Some Problems Concerning the Role of Water and Protons in the Function of Biological Membranes....Pages 92-107
Front Matter....Pages 109-109
Proton Flux Across Model and Biological Membranes....Pages 111-120
Water Diffusion Through Erythrocyte Membranes in Normal and Pathological Subjects: Nuclear Magnetic Resonance Investigations....Pages 121-139
Virally Mediated Changes in Cellular Permeability....Pages 140-166
Transmembrane Calcium Fluxes and Cell Death....Pages 167-176
Front Matter....Pages 177-177
Oxidative Damage in Exercising Muscle and Mitochondria....Pages 179-189
Early Events in Stimulus-Response Coupling Using Neutrophils as a Model System....Pages 190-208
Pathological Sequelae of Irritant-Induced Phagocytosis Exemplified by Pulmonary Emphysema....Pages 209-230
Regulation of Erythropoiesis and Possible Implications of the Cell Membrane....Pages 231-251
Back Matter....Pages 253-261



Content:
Front Matter....Pages i-x
Front Matter....Pages 1-1
Reconstituted Membrane Systems....Pages 3-26
Molecular Aspects of Membrane Fusion....Pages 27-48
Microheterogeneity in Biological Membranes....Pages 49-64
Molecular Composition and Functional Properties of Human Liver Mitochondria....Pages 65-91
Some Problems Concerning the Role of Water and Protons in the Function of Biological Membranes....Pages 92-107
Front Matter....Pages 109-109
Proton Flux Across Model and Biological Membranes....Pages 111-120
Water Diffusion Through Erythrocyte Membranes in Normal and Pathological Subjects: Nuclear Magnetic Resonance Investigations....Pages 121-139
Virally Mediated Changes in Cellular Permeability....Pages 140-166
Transmembrane Calcium Fluxes and Cell Death....Pages 167-176
Front Matter....Pages 177-177
Oxidative Damage in Exercising Muscle and Mitochondria....Pages 179-189
Early Events in Stimulus-Response Coupling Using Neutrophils as a Model System....Pages 190-208
Pathological Sequelae of Irritant-Induced Phagocytosis Exemplified by Pulmonary Emphysema....Pages 209-230
Regulation of Erythropoiesis and Possible Implications of the Cell Membrane....Pages 231-251
Back Matter....Pages 253-261
....
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