Ebook: Chemical Mutagens: Principles and Methods for Their Detection

---

Content:
Front Matter....Pages i-xxvi
Effects of Chemicals on Chromosome-Aberration Production in Male and Female Germ Cells....Pages 1-35
The Use of Immunological Techniques to Detect Cells of Rare Genotype....Pages 37-93
Metabolic Activation Systems in Vitro for Carcinogen/Mutagen Screening Tests....Pages 95-161
Microbial Metabolism of Environmental Chemicals to Mutagens and Carcinogens....Pages 163-188
Short-Term Tests for Chemicals That Promote Aneuploidy....Pages 189-210
Nitrates and Nitrites: Ingestion, Pharmacodynamics, and Toxicology....Pages 211-294
The Relation between Reaction Kinetics and Mutagenic Action of Monofunctional Alkylating Agents in Higher Eukaryotic Systems: Interspecies Comparisons....Pages 295-336
The Human Leukocyte Test System....Pages 337-400
The Activation of Chemicals into Mutagens by Green Plants....Pages 401-420
Unscheduled DNA Synthesis in Mammalian Germ Cells—Its Potential Use in Mutagenicity Testing....Pages 421-445
Aspergillus nidulans—An Organism for Detecting a Range of Genetic Damage....Pages 447-479
Back Matter....Pages 481-497

---

Content:
Front Matter....Pages i-xxvi
Effects of Chemicals on Chromosome-Aberration Production in Male and Female Germ Cells....Pages 1-35
The Use of Immunological Techniques to Detect Cells of Rare Genotype....Pages 37-93
Metabolic Activation Systems in Vitro for Carcinogen/Mutagen Screening Tests....Pages 95-161
Microbial Metabolism of Environmental Chemicals to Mutagens and Carcinogens....Pages 163-188
Short-Term Tests for Chemicals That Promote Aneuploidy....Pages 189-210
Nitrates and Nitrites: Ingestion, Pharmacodynamics, and Toxicology....Pages 211-294
The Relation between Reaction Kinetics and Mutagenic Action of Monofunctional Alkylating Agents in Higher Eukaryotic Systems: Interspecies Comparisons....Pages 295-336
The Human Leukocyte Test System....Pages 337-400
The Activation of Chemicals into Mutagens by Green Plants....Pages 401-420
Unscheduled DNA Synthesis in Mammalian Germ Cells—Its Potential Use in Mutagenicity Testing....Pages 421-445
Aspergillus nidulans—An Organism for Detecting a Range of Genetic Damage....Pages 447-479
Back Matter....Pages 481-497
....