Ebook: Biophysics and Structure to Counter Threats and Challenges
Author: Axel T. Brunger Pavel Strop Marija Vrljic (auth.) Joseph D. Puglisi Manolia V. Margaris (eds.)
- Tags: Biophysics and Biological Physics, Solid State Physics, Crystallography, Biotechnology, Theoretical and Computational Chemistry
- Series: NATO Science for Peace and Security Series B: Physics and Biophysics
- Year: 2013
- Publisher: Springer Netherlands
- Edition: 1
- Language: English
- pdf
This ASI brought together a diverse group of experts who span virology, biology, biophysics, chemistry, physics and engineering. Prominent lecturers representing world renowned scientists from nine (9) different countries, and students from around the world representing eighteen (18) countries, participated in the ASI organized by Professors Joseph Puglisi (Stanford University, USA) and Alexander Arseniev (Moscow, RU).
The central hypothesis underlying this ASI was that interdisciplinary research, merging principles of physics, chemistry and biology, can drive new discovery in detecting and fighting chemical and bioterrorism agents, lead to cleaner environments and improved energy sources, and help propel development in NATO partner countries. At the end of the ASI students had an appreciation of how to apply each technique to their own particular research problem and to demonstrate that multifaceted approaches and new technologies are needed to solve the biological challenges of our time. The course succeeded in training a new generation of biologists and chemists who will probe the molecular basis for life and disease.
This ASI brought together a diverse group of experts who span virology, biology, biophysics, chemistry, physics and engineering. Prominent lecturers representing world renowned scientists from nine (9) different countries, and students from around the world representing eighteen (18) countries, participated in the ASI organized by Professors Joseph Puglisi (Stanford University, USA) and Alexander Arseniev (Moscow, RU).
The central hypothesis underlying this ASI was that interdisciplinary research, merging principles of physics, chemistry and biology, can drive new discovery in detecting and fighting chemical and bioterrorism agents, lead to cleaner environments and improved energy sources, and help propel development in NATO partner countries. At the end of the ASI students had an appreciation of how to apply each technique to their own particular research problem and to demonstrate that multifaceted approaches and new technologies are needed to solve the biological challenges of our time. The course succeeded in training a new generation of biologists and chemists who will probe the molecular basis for life and disease.
This ASI brought together a diverse group of experts who span virology, biology, biophysics, chemistry, physics and engineering. Prominent lecturers representing world renowned scientists from nine (9) different countries, and students from around the world representing eighteen (18) countries, participated in the ASI organized by Professors Joseph Puglisi (Stanford University, USA) and Alexander Arseniev (Moscow, RU).
The central hypothesis underlying this ASI was that interdisciplinary research, merging principles of physics, chemistry and biology, can drive new discovery in detecting and fighting chemical and bioterrorism agents, lead to cleaner environments and improved energy sources, and help propel development in NATO partner countries. At the end of the ASI students had an appreciation of how to apply each technique to their own particular research problem and to demonstrate that multifaceted approaches and new technologies are needed to solve the biological challenges of our time. The course succeeded in training a new generation of biologists and chemists who will probe the molecular basis for life and disease.
Content:
Front Matter....Pages i-x
Macromolecular Models by Single Molecule FRET....Pages 1-19
System-Specific Scoring Functions: Application to Guanine-Containing Ligands and Thrombin....Pages 21-37
Large DNA Template Dependent Error Variation During Transcription....Pages 39-57
Structures of Novel HIV-Inactivating Lectins....Pages 59-67
Fluorescence Resonance Energy Transfer Studies of Structure and Dynamics in Nucleic Acids....Pages 69-82
An Introduction to Macromolecular Crystallography Through Parable and Analogy....Pages 83-96
Using NMR to Determine the Conformation of the HIV Reverse Transcription Initiation Complex....Pages 97-119
Approaches to Protein-Ligand Structure Determination by NMR Spectroscopy: Applications in Drug Binding to the Cardiac Regulatory Protein Troponin C....Pages 121-134
How Do Nascent Proteins Emerge from the Ribosome?....Pages 135-141
Course Abstracts....Pages 143-165
Back Matter....Pages 167-169
This ASI brought together a diverse group of experts who span virology, biology, biophysics, chemistry, physics and engineering. Prominent lecturers representing world renowned scientists from nine (9) different countries, and students from around the world representing eighteen (18) countries, participated in the ASI organized by Professors Joseph Puglisi (Stanford University, USA) and Alexander Arseniev (Moscow, RU).
The central hypothesis underlying this ASI was that interdisciplinary research, merging principles of physics, chemistry and biology, can drive new discovery in detecting and fighting chemical and bioterrorism agents, lead to cleaner environments and improved energy sources, and help propel development in NATO partner countries. At the end of the ASI students had an appreciation of how to apply each technique to their own particular research problem and to demonstrate that multifaceted approaches and new technologies are needed to solve the biological challenges of our time. The course succeeded in training a new generation of biologists and chemists who will probe the molecular basis for life and disease.
Content:
Front Matter....Pages i-x
Macromolecular Models by Single Molecule FRET....Pages 1-19
System-Specific Scoring Functions: Application to Guanine-Containing Ligands and Thrombin....Pages 21-37
Large DNA Template Dependent Error Variation During Transcription....Pages 39-57
Structures of Novel HIV-Inactivating Lectins....Pages 59-67
Fluorescence Resonance Energy Transfer Studies of Structure and Dynamics in Nucleic Acids....Pages 69-82
An Introduction to Macromolecular Crystallography Through Parable and Analogy....Pages 83-96
Using NMR to Determine the Conformation of the HIV Reverse Transcription Initiation Complex....Pages 97-119
Approaches to Protein-Ligand Structure Determination by NMR Spectroscopy: Applications in Drug Binding to the Cardiac Regulatory Protein Troponin C....Pages 121-134
How Do Nascent Proteins Emerge from the Ribosome?....Pages 135-141
Course Abstracts....Pages 143-165
Back Matter....Pages 167-169
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