Ebook: Reproductive Processes and Contraception

This monograph represents the eighth sponsored by the International Society for Biochemical Endocrinology. The topics should be of interest to basic research scientists, medical practitioners, and students of repro­ ductive biology. It complements our monograph published in 1979 on Structure and Function of the Gonadotropins. The monograph is organized in ten topic areas relative to the general theme of reproduction and contraception. There are several chapters in each area. Obviously, all aspects of each area could not be covered. An attempt was made to seek interesting basic research ideas and concepts that might in the future be applicable to fertility regulation. The topics are: interactions in gonadotropin regulation; GnRH analogues as contra­ ceptive agents; receptors in cellular localization of hormones; uterine and mammary receptors; germ-cell regulation and secretory proteins; control mechanisms and metabolic regulations; hCG peptides and anti­ sera as antifertility agents; ieutinization, oocyte maturation, and early pregnancy; steroids and cell growth; and finally, prostaglandins and cell function. The studies encompass many disciplines and techniques in anatomy, physiology, biochemistry, and endocrinology in animals and humans, both in vitro and in vivo. A conference of contributors was held in Maine at the Asticou Inn in Northeast Harbor during the week of September 9-13, 1979. The chapters as written for the monograph were presented for discussion by the participants, who were selected for their knowledge of, and contri­ butions to, this area of scientific investigation.

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Content:
Front Matter....Pages i-xxiii
Front Matter....Pages 1-1
Control of Gonadotropin and Prolactin Secretion in Rhesus Monkeys and Rodents....Pages 3-25
Regulation of LH-RH Secretion by Gonadal Steroids and Catecholamines....Pages 27-45
Sensitivity of Pituitary Gonadotropic Cells and Gonads to Hormones....Pages 47-89
Front Matter....Pages 91-91
Antifertility Effects of LH-RH and Its Agonists....Pages 93-108
Fertility and Antifertility Effects of LH-RH and Its Agonists....Pages 109-141
Front Matter....Pages 143-160
Stable and Specific Tracers....Pages 161-161
Specific Inhibitors of Androgen Binding to the Androgen-Binding Protein (ABP)....Pages 163-179
Profiles of Target-Cell Prolactin and Adrenocorticotropin during Lactational Diestrus....Pages 181-193
Gonadotropin-like Immunoreactivity in the Rat Ovary....Pages 195-213
Front Matter....Pages 215-230
Hormonal Modulation of Progesterone Receptors....Pages 231-231
Hormonal Control of Steroid Receptors in Human Endometrium during the Menstrual Cycle....Pages 233-255
Parturition, Lactation, and the Regulation of Oxytocin Receptors....Pages 257-279
Front Matter....Pages 281-303
Control of Spermatogonial Multiplication....Pages 305-305
Secretory Proteins in the Male Reproductive System....Pages 307-331
Monitoring the Metabolic Rate of Germ Cells and Sperm....Pages 333-352
Study of a Glycoprotein Produced by the Rat Epididymis....Pages 353-391
Front Matter....Pages 393-405
The Use of Isopropyl-N-phenylcarbamate as a Potential Contraceptive....Pages 407-407
Interaction between Prolactin and Gonadotropin Secretion....Pages 409-420
Interactions among LH, FSH, PRL, LH-RH, and Sex Steroids in the Control of Testicular LH, FSH, and PRL Receptors in the Rat....Pages 421-447
Front Matter....Pages 449-469
Inhibition of Testicular Androgen Biosynthesis by Treatment with LH-RH Agonists....Pages 407-407
Gonadotropic Stimulation of Enzymes Involved in Testicular Growth....Pages 471-491
Uterine Diamine Oxidase....Pages 493-507
Front Matter....Pages 509-519
Specific Antisera to Human Choriogonadotropin....Pages 521-521
Development of Specific Antisera for Human Chorionic Gonadotropin....Pages 523-539
Isolation and Characterization of an “hCG”-like Protein from Bacteria....Pages 541-561
Front Matter....Pages 563-577
Comparative Approach to Mechanisms in the Maintenance of Early Pregnancy....Pages 579-579
Porcine and Human Ovarian Nonsteroidal Follicular Regulators....Pages 581-617
Front Matter....Pages 619-645
Estrogen-Induced Growth of Uterine Cells....Pages 647-647
Front Matter....Pages 649-674
Prostaglandin-Induced Luteolysis in the Superluteinized Rat Ovary....Pages 675-675
Role of Prostaglandins in Leydig-Cell Stimulation by hCG and Leydig-Cell Function....Pages 677-690
Back Matter....Pages 691-711
....Pages 713-731