Ebook: Designing Receptors for the Next Generation of Biosensors
- Tags: Industrial Chemistry/Chemical Engineering, Analytical Chemistry, Medicinal Chemistry, Bioorganic Chemistry, Biomedical Engineering, Biomaterials
- Series: Springer Series on Chemical Sensors and Biosensors 12
- Year: 2013
- Publisher: Springer-Verlag Berlin Heidelberg
- Edition: 1
- Language: English
- pdf
Despite achievements in the application of enzymes, antibodies and biological receptors to diagnostics and sensing, the last two decades have also witnessed the emergence of a number of alternative technologies based on synthetic chemistry. This volume shows how synthetic receptors can be designed with characteristics that make them attractive alternatives to biological molecules in the sensory and diagnostics fields, with contributions from leading experts in the area. Subjects covered include synthetic receptors for a range of biomolecules, the use of antimicrobial peptides for the detection of pathogenic microorganisms, the development of molecularly imprinted polymer (MIP) nanoparticles, the in silico design of MIPs and MIP-based sensors, and two chapters examining the development of sensors from an industrial point of view. The particular focus of all chapters is on practical aspects, either in the development process or the applications of the synthesized materials. This book will serve as an important reference work for business leaders and technology experts in the sensors and diagnostics sector.
Despite achievements in the application of enzymes, antibodies and biological receptors to diagnostics and sensing, the last two decades have also witnessed the emergence of a number of alternative technologies based on synthetic chemistry. This volume shows how synthetic receptors can be designed with characteristics that make them attractive alternatives to biological molecules in the sensory and diagnostics fields, with contributions from leading experts in the area. Subjects covered include synthetic receptors for a range of biomolecules, the use of antimicrobial peptides for the detection of pathogenic microorganisms, the development of molecularly imprinted polymer (MIP) nanoparticles, the in silico design of MIPs and MIP-based sensors, and two chapters examining the development of sensors from an industrial point of view. The particular focus of all chapters is on practical aspects, either in the development process or the applications of the synthesized materials. This book will serve as an important reference work for business leaders and technology experts in the sensors and diagnostics sector.
Despite achievements in the application of enzymes, antibodies and biological receptors to diagnostics and sensing, the last two decades have also witnessed the emergence of a number of alternative technologies based on synthetic chemistry. This volume shows how synthetic receptors can be designed with characteristics that make them attractive alternatives to biological molecules in the sensory and diagnostics fields, with contributions from leading experts in the area. Subjects covered include synthetic receptors for a range of biomolecules, the use of antimicrobial peptides for the detection of pathogenic microorganisms, the development of molecularly imprinted polymer (MIP) nanoparticles, the in silico design of MIPs and MIP-based sensors, and two chapters examining the development of sensors from an industrial point of view. The particular focus of all chapters is on practical aspects, either in the development process or the applications of the synthesized materials. This book will serve as an important reference work for business leaders and technology experts in the sensors and diagnostics sector.
Content:
Front Matter....Pages i-xii
Multichannel Sensors Based on Biphenyl and Cyclohexane Conformational Changes....Pages 1-32
Learning from Proteins and Drugs: Receptors That Mimic Biomedically Important Binding Motifs....Pages 33-51
Molecular Recognition of Nucleotides....Pages 53-65
Molecular Recognition of Oligopeptides and Protein Surfaces....Pages 67-84
Antimicrobial Peptides for Detection and Diagnostic Assays....Pages 85-104
Plastic Antibodies....Pages 105-129
Computational Approaches in the Design of Synthetic Receptors....Pages 131-165
MIP Sensors on the Way to Real-World Applications....Pages 167-187
Molecularly Imprinted Au Nanoparticle Composites for Selective Sensing Applications....Pages 189-212
Design and Development of In Vivo Sensor Systems: The Long and Tortured Road to a Self-Contained, Implantable Glucose Sensor for Diabetes Management....Pages 213-238
Evolving Trends in Transition Metal-Modified Receptor Design and Function....Pages 239-259
Back Matter....Pages 261-264
Despite achievements in the application of enzymes, antibodies and biological receptors to diagnostics and sensing, the last two decades have also witnessed the emergence of a number of alternative technologies based on synthetic chemistry. This volume shows how synthetic receptors can be designed with characteristics that make them attractive alternatives to biological molecules in the sensory and diagnostics fields, with contributions from leading experts in the area. Subjects covered include synthetic receptors for a range of biomolecules, the use of antimicrobial peptides for the detection of pathogenic microorganisms, the development of molecularly imprinted polymer (MIP) nanoparticles, the in silico design of MIPs and MIP-based sensors, and two chapters examining the development of sensors from an industrial point of view. The particular focus of all chapters is on practical aspects, either in the development process or the applications of the synthesized materials. This book will serve as an important reference work for business leaders and technology experts in the sensors and diagnostics sector.
Content:
Front Matter....Pages i-xii
Multichannel Sensors Based on Biphenyl and Cyclohexane Conformational Changes....Pages 1-32
Learning from Proteins and Drugs: Receptors That Mimic Biomedically Important Binding Motifs....Pages 33-51
Molecular Recognition of Nucleotides....Pages 53-65
Molecular Recognition of Oligopeptides and Protein Surfaces....Pages 67-84
Antimicrobial Peptides for Detection and Diagnostic Assays....Pages 85-104
Plastic Antibodies....Pages 105-129
Computational Approaches in the Design of Synthetic Receptors....Pages 131-165
MIP Sensors on the Way to Real-World Applications....Pages 167-187
Molecularly Imprinted Au Nanoparticle Composites for Selective Sensing Applications....Pages 189-212
Design and Development of In Vivo Sensor Systems: The Long and Tortured Road to a Self-Contained, Implantable Glucose Sensor for Diabetes Management....Pages 213-238
Evolving Trends in Transition Metal-Modified Receptor Design and Function....Pages 239-259
Back Matter....Pages 261-264
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