Ebook: Micro and Nano Flow Systems for Bioanalysis
- Tags: Biomedical Engineering, Soft and Granular Matter Complex Fluids and Microfluidics, Molecular Medicine, Medical and Radiation Physics, Nanotechnology and Microengineering, Engineering Fluid Dynamics
- Series: Bioanalysis 2
- Year: 2013
- Publisher: Springer-Verlag New York
- Edition: 1
- Language: English
- pdf
Micro and Nano Flow Systems for Bioanalysis addresses the latest developments in biomedical engineering at very small scales. It shows how organic systems require multi-scale understanding in the broadest sensewhether the approach is experimental or mathematical, and whether the physiological state is healthy or diseased. Micro-and nano-fluidics represent key areas of translational research in which state-of-the-art engineering processes and devices are applied to bedside monitoring and treatment. By applying conventional micro- and nano-engineering to complex organic solids, fluids, and their interactions, leading researchers from throughout the world describe methods and techniques with great potential for use in medicine and clinical practice. Coverage includes the seeming plethora of new, fine-scale optical methods for measuring blood flow as well as endothelial activation and interaction with tissue. Generic areas of modeling and bioelectronics are also considered. In keeping with the recurring theme of medicine and clinical practice, approximately half of the chapters focus on the specific application of micro- and nano- flow systems to the understanding and treatment of cancer and cardiovascular diseases. This book developed from an Expert Overview Session on "Micro & Nano Flows in Medicine: the way ahead" at the 3rd Micro and Nano Flows Conference (MNF2011) held in Thessaloniki, Greece. Additional chapters were included to enhance the international, state-of-the-art coverage.
Micro and Nano Flow Systems for Bioanalysis addresses the latest developments in biomedical engineering at very small scales. It shows how organic systems require multi-scale understanding in the broadest sense whether the approach is experimental or mathematical, and whether the physiological state is healthy or diseased. Micro-and nano-fluidics represent key areas of translational research in which state-of-the-art engineering processes and devices are applied to bedside monitoring and treatment. By applying conventional micro- and nano-engineering to complex organic solids, fluids, and their interactions, leading researchers from throughout the world describe methods and techniques with great potential for use in medicine and clinical practice. Coverage includes the seeming plethora of new, fine-scale optical methods for measuring blood flow as well as endothelial activation and interaction with tissue. Generic areas of modeling and bioelectronics are also considered. In keeping with the recurring theme of medicine and clinical practice, approximately half of the chapters focus on the specific application of micro- and nano- flow systems to the understanding and treatment of cancer and cardiovascular diseases. This book developed from an Expert Overview Session on "Micro & Nano Flows in Medicine: the way ahead" at the 3rd Micro and Nano Flows Conference (MNF2011) held in Thessaloniki, Greece. Additional chapters were included to enhance the international, state-of-the-art coverage.
Covers a broad range of topics, including ultrascale optical measurement methods and the modeling of multiscale biomedical flows
Explains the underlying biology in areas such as cascades of reacting agents
Includes applications to cardiology and to the detection and treatment of cancer
Provides an overview suitable for a broad audience of bioengineering researchers, students, and clinicians
Micro and Nano Flow Systems for Bioanalysis addresses the latest developments in biomedical engineering at very small scales. It shows how organic systems require multi-scale understanding in the broadest sense whether the approach is experimental or mathematical, and whether the physiological state is healthy or diseased. Micro-and nano-fluidics represent key areas of translational research in which state-of-the-art engineering processes and devices are applied to bedside monitoring and treatment. By applying conventional micro- and nano-engineering to complex organic solids, fluids, and their interactions, leading researchers from throughout the world describe methods and techniques with great potential for use in medicine and clinical practice. Coverage includes the seeming plethora of new, fine-scale optical methods for measuring blood flow as well as endothelial activation and interaction with tissue. Generic areas of modeling and bioelectronics are also considered. In keeping with the recurring theme of medicine and clinical practice, approximately half of the chapters focus on the specific application of micro- and nano- flow systems to the understanding and treatment of cancer and cardiovascular diseases. This book developed from an Expert Overview Session on "Micro & Nano Flows in Medicine: the way ahead" at the 3rd Micro and Nano Flows Conference (MNF2011) held in Thessaloniki, Greece. Additional chapters were included to enhance the international, state-of-the-art coverage.
Covers a broad range of topics, including ultrascale optical measurement methods and the modeling of multiscale biomedical flows
Explains the underlying biology in areas such as cascades of reacting agents
Includes applications to cardiology and to the detection and treatment of cancer
Provides an overview suitable for a broad audience of bioengineering researchers, students, and clinicians
Content:
Front Matter....Pages i-xiii
Iron Oxide Nanoparticles and Derivatives for Biomedical Imaging and Application in Cancer Diagnosis and Therapy....Pages 1-14
Inertial Migration of Cancer Cells in a Microfluidic Device....Pages 15-27
3D Multiscale Modelling of Angiogenesis and Vascular Tumour Growth....Pages 29-48
Microvascular Permeability and Tumor Metastasis....Pages 49-68
Micro Flows in the Cardiopulmonary System: A Surgical Perspective....Pages 69-76
Regulation of Endothelial Activation and Vascular Inflammation by Shear Stress....Pages 77-85
Digital Optical and Scanning Probe Microscopy for Inspection and Manipulation of Biocells....Pages 87-105
Coherent Microscopy and Optical Coherence Tomography for Biomedical Applications....Pages 107-129
Confocal Micro-PIV/PTV Measurements of the Blood Flow in Micro-channels....Pages 131-151
The Lattice Boltzmann Method as a General Framework for Blood Flow Modelling and Simulations....Pages 153-170
Dielectrophoretic Characterization and Continuous Separation of Cells in a PDMS Microfluidic Device with Sidewall Conducting PDMS Composite Electrodes....Pages 171-185
Integrating “Omics” Data for Quantitative and Systems Pharmacology in Translational Oncology....Pages 187-206
Back Matter....Pages 207-211
Micro and Nano Flow Systems for Bioanalysis addresses the latest developments in biomedical engineering at very small scales. It shows how organic systems require multi-scale understanding in the broadest sense whether the approach is experimental or mathematical, and whether the physiological state is healthy or diseased. Micro-and nano-fluidics represent key areas of translational research in which state-of-the-art engineering processes and devices are applied to bedside monitoring and treatment. By applying conventional micro- and nano-engineering to complex organic solids, fluids, and their interactions, leading researchers from throughout the world describe methods and techniques with great potential for use in medicine and clinical practice. Coverage includes the seeming plethora of new, fine-scale optical methods for measuring blood flow as well as endothelial activation and interaction with tissue. Generic areas of modeling and bioelectronics are also considered. In keeping with the recurring theme of medicine and clinical practice, approximately half of the chapters focus on the specific application of micro- and nano- flow systems to the understanding and treatment of cancer and cardiovascular diseases. This book developed from an Expert Overview Session on "Micro & Nano Flows in Medicine: the way ahead" at the 3rd Micro and Nano Flows Conference (MNF2011) held in Thessaloniki, Greece. Additional chapters were included to enhance the international, state-of-the-art coverage.
Covers a broad range of topics, including ultrascale optical measurement methods and the modeling of multiscale biomedical flows
Explains the underlying biology in areas such as cascades of reacting agents
Includes applications to cardiology and to the detection and treatment of cancer
Provides an overview suitable for a broad audience of bioengineering researchers, students, and clinicians
Content:
Front Matter....Pages i-xiii
Iron Oxide Nanoparticles and Derivatives for Biomedical Imaging and Application in Cancer Diagnosis and Therapy....Pages 1-14
Inertial Migration of Cancer Cells in a Microfluidic Device....Pages 15-27
3D Multiscale Modelling of Angiogenesis and Vascular Tumour Growth....Pages 29-48
Microvascular Permeability and Tumor Metastasis....Pages 49-68
Micro Flows in the Cardiopulmonary System: A Surgical Perspective....Pages 69-76
Regulation of Endothelial Activation and Vascular Inflammation by Shear Stress....Pages 77-85
Digital Optical and Scanning Probe Microscopy for Inspection and Manipulation of Biocells....Pages 87-105
Coherent Microscopy and Optical Coherence Tomography for Biomedical Applications....Pages 107-129
Confocal Micro-PIV/PTV Measurements of the Blood Flow in Micro-channels....Pages 131-151
The Lattice Boltzmann Method as a General Framework for Blood Flow Modelling and Simulations....Pages 153-170
Dielectrophoretic Characterization and Continuous Separation of Cells in a PDMS Microfluidic Device with Sidewall Conducting PDMS Composite Electrodes....Pages 171-185
Integrating “Omics” Data for Quantitative and Systems Pharmacology in Translational Oncology....Pages 187-206
Back Matter....Pages 207-211
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