Ebook: Nature’s Versatile Engine: Insect Flight Muscle Inside and Out

Methods for Obtaining X-Ray Diffraction Patterns from Drosophila 198 Diffraction Patterns from Drosophila IFM 203 Concluding Remarks 211 Note Added in Proof 211 17. Functional and Ecological Effects of Isoform Variation in Insect Flight Muscle 214 James H. Marden Abstract 214 Introduction 215 Nature's Versatile Engine 215 The Underlying Genetics: An Underinflated Genome and a Hyperinflated Transcriptome and Proteome 216 Functional Effects of Isoform Variation 219 Alternative Splicing and the Generation of Combinatorial Complexity 220 Functional Consequences of Naturally Occurring Isoform Variation 220 18. Muscle Systems Design and Integration 230 Fritz- OlafLehmann Abstract 230 Power Requirements for Flight 230 Power Reduction 233 Power Constraints on Steering Capacity 234 Balancing Power and Control 236 Changes in Muscle Efficiency in Vivo 238 Concluding Remarks 239 From the Inside Out 19. Molecular Assays for Acto-Myosin Interactions 242 John C. Sparrow and Michael A. Geeves Abstract 242 Introduction 242 Myosin Purification and Preparation of the SI Fragment 243 Purification of Flight Muscle Actin 244 Assays of Myosin and Acto-Myosin 244 Major Conclusions Relating to the Enzymatic Properties of Insect Flight Muscle Acto-Myosin 247 Major Questions about Insect Flight Muscle Acto-Myosin Kinetics That Remain 249 20.

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This first edition book integrates knowledge from all disciplines that study muscle function, from single molecule biophysics to flight aerodynamics. Nature’s Versatile Engine, is an expose of up-to-date advances in muscle research from the molecular to the organismal, covering all levels of biological organization. While the main emphasis is on Drosophila melanogaster (as it is the organism most widely studied), other species of flying insects are also covered. Because of its multidisciplinary nature, the book should appeal to just about anyone with an interest in muscle biology or insect flight.

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This first edition book integrates knowledge from all disciplines that study muscle function, from single molecule biophysics to flight aerodynamics. Nature’s Versatile Engine, is an expose of up-to-date advances in muscle research from the molecular to the organismal, covering all levels of biological organization. While the main emphasis is on Drosophila melanogaster (as it is the organism most widely studied), other species of flying insects are also covered. Because of its multidisciplinary nature, the book should appeal to just about anyone with an interest in muscle biology or insect flight.

Content:
Front Matter....Pages i-xxii
Front Matter....Pages 1-1
The Contributions of Genetics to the Study of Insect Flight Muscle Function....Pages 2-15
3D Structure of Myosin Crossbridges in Insect Flight Muscle....Pages 16-33
Comparative Physiology of Insect Flight Muscle....Pages 34-43
Stretch Activation....Pages 44-60
Front Matter....Pages 61-61
Myosin....Pages 62-75
Paramyosin and Miniparamyosin....Pages 76-85
Novel Myosin Associated Proteins....Pages 86-96
Structure of the Insect Thick Filaments....Pages 97-109
Actin and Arthrin....Pages 110-125
Troponin, Tropomyosin and GST-2....Pages 126-140
The Thin Filament in Insect Flight Muscle....Pages 141-149
The Insect Z-Band....Pages 150-166
Projectin, the Elastic Protein of the C-Filaments....Pages 167-176
Some Functions of Proteins from the Drosophila sallimus (sls) Gene....Pages 177-186
Front Matter....Pages 187-187
Sustained High Power Performance....Pages 188-196
X-Ray Diffraction of Indirect Flight Muscle from Drosophila in Vivo....Pages 197-213
Functional and Ecological Effects of Isoform Variation in Insect Flight Muscle....Pages 214-229
Muscle Systems Design and Integration....Pages 230-241
Molecular Assays for Acto-Myosin Interactions....Pages 242-250
Insect Flight Muscle Chemomechanics....Pages 251-269
Back Matter....Pages 285-288
Mapping Myofibrillar Protein Interactions by Mutational Proteomics....Pages 270-283

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This first edition book integrates knowledge from all disciplines that study muscle function, from single molecule biophysics to flight aerodynamics. Nature’s Versatile Engine, is an expose of up-to-date advances in muscle research from the molecular to the organismal, covering all levels of biological organization. While the main emphasis is on Drosophila melanogaster (as it is the organism most widely studied), other species of flying insects are also covered. Because of its multidisciplinary nature, the book should appeal to just about anyone with an interest in muscle biology or insect flight.

Content:
Front Matter....Pages i-xxii
Front Matter....Pages 1-1
The Contributions of Genetics to the Study of Insect Flight Muscle Function....Pages 2-15
3D Structure of Myosin Crossbridges in Insect Flight Muscle....Pages 16-33
Comparative Physiology of Insect Flight Muscle....Pages 34-43
Stretch Activation....Pages 44-60
Front Matter....Pages 61-61
Myosin....Pages 62-75
Paramyosin and Miniparamyosin....Pages 76-85
Novel Myosin Associated Proteins....Pages 86-96
Structure of the Insect Thick Filaments....Pages 97-109
Actin and Arthrin....Pages 110-125
Troponin, Tropomyosin and GST-2....Pages 126-140
The Thin Filament in Insect Flight Muscle....Pages 141-149
The Insect Z-Band....Pages 150-166
Projectin, the Elastic Protein of the C-Filaments....Pages 167-176
Some Functions of Proteins from the Drosophila sallimus (sls) Gene....Pages 177-186
Front Matter....Pages 187-187
Sustained High Power Performance....Pages 188-196
X-Ray Diffraction of Indirect Flight Muscle from Drosophila in Vivo....Pages 197-213
Functional and Ecological Effects of Isoform Variation in Insect Flight Muscle....Pages 214-229
Muscle Systems Design and Integration....Pages 230-241
Molecular Assays for Acto-Myosin Interactions....Pages 242-250
Insect Flight Muscle Chemomechanics....Pages 251-269
Back Matter....Pages 285-288
Mapping Myofibrillar Protein Interactions by Mutational Proteomics....Pages 270-283
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