Ebook: Biomedical EPR, Part A: Free Radicals, Metals, Medicine, and Physiology
- Tags: Imaging / Radiology, Biochemistry general, Biophysics/Biomedical Physics, Atoms Molecules Clusters and Plasmas, Physical Chemistry
- Series: Biological Magnetic Resonance 23
- Year: 2005
- Publisher: Springer US
- Edition: 1
- Language: English
- pdf
Biomedical EPR – Part A focuses on applications of EPR spectroscopy in the areas of free radicals, metals, medicine, and physiology. The book celebrates the 70th birthday of Prof. James S. Hyde, Medical College of Wisconsin, and his contributions to this field. Chapters are written to provide introductory material for new-comers to the field which lead into up-to-date reviews that provide perspective on the wide range of questions that can be addressed by EPR.
Key Features:
Free Radicals in Medicine
Radicals in vivo and in Model Systems, and their Study by Spin Trapping
In vivo EPR, including Oximetry and Imaging
Time Domain EPR at Radio Frequencies
EPR of Copper Complexes: Motion and Frequency Dependence
Time Domain EPR and Electron Spin Echo Envelope Modulation
About the Editors:
Prof. Sandra S. Eaton is John Evans Professor in the Department of Chemistry and Biochemistry at the University of Denver. Her research interests include distance measurements in proteins, EPR of metal ions in biological systems, electron spin relaxation times, and EPR instrumentation. The Eatons co-organize an annual EPR Symposium in Denver.
Prof. Gareth R. Eaton is John Evans Professor in the Department of Chemistry and Biochemistry at the University of Denver. His research interests include EPR instrumentation, distance measurements in proteins, EPR of metal ions in biological systems, and electron spin relaxation times.
Dr. Lawrence J. Berliner is currently Professor and Chair of the Department of Chemistry and Biochemistry at the University of Denver after retiring from Ohio State University, where he spent a 32-year career in the area of biological magnetic resonance (EPR and NMR). He is the Series Editor for Biological Magnetic Resonance, which he launched in 1979.
Biomedical EPR – Part A focuses on applications of EPR spectroscopy in the areas of free radicals, metals, medicine, and physiology. The book celebrates the 70th birthday of Prof. James S. Hyde, Medical College of Wisconsin, and his contributions to this field. Chapters are written to provide introductory material for new-comers to the field which lead into up-to-date reviews that provide perspective on the wide range of questions that can be addressed by EPR.
Key Features:
Free Radicals in Medicine
Radicals in vivo and in Model Systems, and their Study by Spin Trapping
In vivo EPR, including Oximetry and Imaging
Time Domain EPR at Radio Frequencies
EPR of Copper Complexes: Motion and Frequency Dependence
Time Domain EPR and Electron Spin Echo Envelope Modulation
About the Editors:
Prof. Sandra S. Eaton is John Evans Professor in the Department of Chemistry and Biochemistry at the University of Denver. Her research interests include distance measurements in proteins, EPR of metal ions in biological systems, electron spin relaxation times, and EPR instrumentation. The Eatons co-organize an annual EPR Symposium in Denver.
Prof. Gareth R. Eaton is John Evans Professor in the Department of Chemistry and Biochemistry at the University of Denver. His research interests include EPR instrumentation, distance measurements in proteins, EPR of metal ions in biological systems, and electron spin relaxation times.
Dr. Lawrence J. Berliner is currently Professor and Chair of the Department of Chemistry and Biochemistry at the University of Denver after retiring from Ohio State University, where he spent a 32-year career in the area of biological magnetic resonance (EPR and NMR). He is the Series Editor for Biological Magnetic Resonance, which he launched in 1979.
Biomedical EPR – Part A focuses on applications of EPR spectroscopy in the areas of free radicals, metals, medicine, and physiology. The book celebrates the 70th birthday of Prof. James S. Hyde, Medical College of Wisconsin, and his contributions to this field. Chapters are written to provide introductory material for new-comers to the field which lead into up-to-date reviews that provide perspective on the wide range of questions that can be addressed by EPR.
Key Features:
Free Radicals in Medicine
Radicals in vivo and in Model Systems, and their Study by Spin Trapping
In vivo EPR, including Oximetry and Imaging
Time Domain EPR at Radio Frequencies
EPR of Copper Complexes: Motion and Frequency Dependence
Time Domain EPR and Electron Spin Echo Envelope Modulation
About the Editors:
Prof. Sandra S. Eaton is John Evans Professor in the Department of Chemistry and Biochemistry at the University of Denver. Her research interests include distance measurements in proteins, EPR of metal ions in biological systems, electron spin relaxation times, and EPR instrumentation. The Eatons co-organize an annual EPR Symposium in Denver.
Prof. Gareth R. Eaton is John Evans Professor in the Department of Chemistry and Biochemistry at the University of Denver. His research interests include EPR instrumentation, distance measurements in proteins, EPR of metal ions in biological systems, and electron spin relaxation times.
Dr. Lawrence J. Berliner is currently Professor and Chair of the Department of Chemistry and Biochemistry at the University of Denver after retiring from Ohio State University, where he spent a 32-year career in the area of biological magnetic resonance (EPR and NMR). He is the Series Editor for Biological Magnetic Resonance, which he launched in 1979.
Content:
Front Matter....Pages i-xxvi
Introduction....Pages 3-5
An Incomplete History of Jim Hyde and the EPR Center at MCW....Pages 7-22
Free Radicals and Medicine....Pages 25-74
Superoxide Generation from Nitric Oxide Synthase....Pages 75-91
In Vivo Spin Trapping of Free Radical Metabolites of Drugs and Toxic Chemicals Utilizing Ex Vivo Detection....Pages 93-109
Post Processing Strategies in EPR Spin-Trapping Studies....Pages 111-123
Biophysical Studies of Melanin....Pages 125-146
Application of Spin Labels To Membrane Bioenergetics....Pages 147-194
EPR Spectroscopy of Function In Vivo ....Pages 197-228
EPR Oximetry in Biological and Model Samples....Pages 229-282
In vivo EPR Imaging....Pages 283-319
Time-Domain Radio Frequency EPR Imaging....Pages 321-382
Copper Biomolecules in Solution....Pages 385-416
Low Frequency EPR of Cu2+ in Proteins....Pages 417-454
Electron Spin-Echo Envelope Modulation Studies Of 14N In Biological Systems....Pages 455-491
Back Matter....Pages 493-522
Biomedical EPR – Part A focuses on applications of EPR spectroscopy in the areas of free radicals, metals, medicine, and physiology. The book celebrates the 70th birthday of Prof. James S. Hyde, Medical College of Wisconsin, and his contributions to this field. Chapters are written to provide introductory material for new-comers to the field which lead into up-to-date reviews that provide perspective on the wide range of questions that can be addressed by EPR.
Key Features:
Free Radicals in Medicine
Radicals in vivo and in Model Systems, and their Study by Spin Trapping
In vivo EPR, including Oximetry and Imaging
Time Domain EPR at Radio Frequencies
EPR of Copper Complexes: Motion and Frequency Dependence
Time Domain EPR and Electron Spin Echo Envelope Modulation
About the Editors:
Prof. Sandra S. Eaton is John Evans Professor in the Department of Chemistry and Biochemistry at the University of Denver. Her research interests include distance measurements in proteins, EPR of metal ions in biological systems, electron spin relaxation times, and EPR instrumentation. The Eatons co-organize an annual EPR Symposium in Denver.
Prof. Gareth R. Eaton is John Evans Professor in the Department of Chemistry and Biochemistry at the University of Denver. His research interests include EPR instrumentation, distance measurements in proteins, EPR of metal ions in biological systems, and electron spin relaxation times.
Dr. Lawrence J. Berliner is currently Professor and Chair of the Department of Chemistry and Biochemistry at the University of Denver after retiring from Ohio State University, where he spent a 32-year career in the area of biological magnetic resonance (EPR and NMR). He is the Series Editor for Biological Magnetic Resonance, which he launched in 1979.
Content:
Front Matter....Pages i-xxvi
Introduction....Pages 3-5
An Incomplete History of Jim Hyde and the EPR Center at MCW....Pages 7-22
Free Radicals and Medicine....Pages 25-74
Superoxide Generation from Nitric Oxide Synthase....Pages 75-91
In Vivo Spin Trapping of Free Radical Metabolites of Drugs and Toxic Chemicals Utilizing Ex Vivo Detection....Pages 93-109
Post Processing Strategies in EPR Spin-Trapping Studies....Pages 111-123
Biophysical Studies of Melanin....Pages 125-146
Application of Spin Labels To Membrane Bioenergetics....Pages 147-194
EPR Spectroscopy of Function In Vivo ....Pages 197-228
EPR Oximetry in Biological and Model Samples....Pages 229-282
In vivo EPR Imaging....Pages 283-319
Time-Domain Radio Frequency EPR Imaging....Pages 321-382
Copper Biomolecules in Solution....Pages 385-416
Low Frequency EPR of Cu2+ in Proteins....Pages 417-454
Electron Spin-Echo Envelope Modulation Studies Of 14N In Biological Systems....Pages 455-491
Back Matter....Pages 493-522
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