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This set of lecture notes gives a first coherent account of a novel aspect of the living world that can be called biological information. The book presents both a pedagogical and state-of-the art roadmap of this rapidly evolving area and covers the whole field, from information which is encoded in the molecular genetic code to the description of large-scale evolution of complex species networks. The book will prove useful for all those who work at the interface of biology, physics and information science.




This set of lecture notes gives a first coherent account of a novel aspect of the living world that can be called biological information. The book presents both a pedagogical and state-of-the art roadmap of this rapidly evolving area and covers the whole field, from information which is encoded in the molecular genetic code to the description of large-scale evolution of complex species networks. The book will prove useful for all those who work at the interface of biology, physics and information science.


This set of lecture notes gives a first coherent account of a novel aspect of the living world that can be called biological information. The book presents both a pedagogical and state-of-the art roadmap of this rapidly evolving area and covers the whole field, from information which is encoded in the molecular genetic code to the description of large-scale evolution of complex species networks. The book will prove useful for all those who work at the interface of biology, physics and information science.
Content:
Front Matter....Pages I-VIII
Statistical significance and extremal ensemble of gapped local hybrid alignment....Pages 3-21
On the design of optimization criteria for multiple sequence alignment....Pages 22-36
Red queen dynamics and the evolution of translational redundancy and degeneracy....Pages 37-54
A testable genotype-phenotype map: modeling evolution of RNA molecules....Pages 55-81
Evolutionary perspectives on protein structure, stability, and functionality....Pages 82-107
The statistical approach to molecular phylogeny: Evidence for a nonhyperthermophilic common ancestor....Pages 111-121
Principles of cophylogenetic maps....Pages 122-147
Accounting for phylogenetic uncertainty in comparative studies of evolution and adaptation....Pages 148-161
The‘ shape’ of phylogenies under simple random speciation models....Pages 162-180
Fitness landscapes....Pages 183-204
Tempo and mode in quasispecies evolution....Pages 205-216
Multilevel processes in evolution and development: Computational models and biological insights....Pages 217-239
Evolutionary strategies for solving optimization problems....Pages 240-254
Review of biological ageing on the computer....Pages 255-267
Spatio-temporal modes of speciation....Pages 268-278
Food web structure and the evolution of ecological communities....Pages 281-298
Dynamics and topology of species networks....Pages 299-311
Modelling macroevolutionary patterns: An ecological perspective....Pages 312-337


This set of lecture notes gives a first coherent account of a novel aspect of the living world that can be called biological information. The book presents both a pedagogical and state-of-the art roadmap of this rapidly evolving area and covers the whole field, from information which is encoded in the molecular genetic code to the description of large-scale evolution of complex species networks. The book will prove useful for all those who work at the interface of biology, physics and information science.
Content:
Front Matter....Pages I-VIII
Statistical significance and extremal ensemble of gapped local hybrid alignment....Pages 3-21
On the design of optimization criteria for multiple sequence alignment....Pages 22-36
Red queen dynamics and the evolution of translational redundancy and degeneracy....Pages 37-54
A testable genotype-phenotype map: modeling evolution of RNA molecules....Pages 55-81
Evolutionary perspectives on protein structure, stability, and functionality....Pages 82-107
The statistical approach to molecular phylogeny: Evidence for a nonhyperthermophilic common ancestor....Pages 111-121
Principles of cophylogenetic maps....Pages 122-147
Accounting for phylogenetic uncertainty in comparative studies of evolution and adaptation....Pages 148-161
The‘ shape’ of phylogenies under simple random speciation models....Pages 162-180
Fitness landscapes....Pages 183-204
Tempo and mode in quasispecies evolution....Pages 205-216
Multilevel processes in evolution and development: Computational models and biological insights....Pages 217-239
Evolutionary strategies for solving optimization problems....Pages 240-254
Review of biological ageing on the computer....Pages 255-267
Spatio-temporal modes of speciation....Pages 268-278
Food web structure and the evolution of ecological communities....Pages 281-298
Dynamics and topology of species networks....Pages 299-311
Modelling macroevolutionary patterns: An ecological perspective....Pages 312-337
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