Ebook: Principles and Methods for Accelerated Catalyst Design and Testing

High throughput experimentation has met great success in drug design but it has, so far, been scarcely used in the field ofcatalysis. We present in this book the outcome of a NATO ASI meeting that was held in Vilamoura, Portugal, between July 15 and 28, 2001, with the objective of delineating and consolidating the principles and methods underpinning accelerated catalyst design, evaluation, and development. There is a need to make the underlying principles of this new methodology more widely understood and to make it available in a coherent and integrated format. The latter objective is particularly important to the young scientists who will constitute the new catalysis researchers generation. Indeed, this field which is at the frontier offundamental science and may be a renaissance for catalysis, is one which is much more complex than classical catalysis itself. It implies a close collaboration between scientists from many disciplines (chemistry, physics, chemical and mechanical engineering, automation, robotics, and scientific computing in general). In addition, this emerging area of science is also of paramount industrial importance, as progress in this area would collapse the time necessary to discover new catalysts or improve existing ones.

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The pace of development in the chemical industry is increasing steadily, bringing with it a corresponding need to develop catalysts as rapidly as possible. High throughput experimentation has had great success in drug design but hitherto it has scarcely been used in the catalysis field. There is thus a need to make the underlying principles of this methodology more widely understood, in a coherent, integrated format. The present book fulfils such a need as it delineates and consolidates the principles and methods underlying accelerated catalyst design and testing. The main challenges for progress in the field are also identified.

An indispensable book for all those working in catalytic process analysis and development, in industry and the academic laboratory. Contains an extensive review of catalytic principles, making the book also suitable for postgraduate students seeking to pursue a career in the catalysis field.

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The pace of development in the chemical industry is increasing steadily, bringing with it a corresponding need to develop catalysts as rapidly as possible. High throughput experimentation has had great success in drug design but hitherto it has scarcely been used in the catalysis field. There is thus a need to make the underlying principles of this methodology more widely understood, in a coherent, integrated format. The present book fulfils such a need as it delineates and consolidates the principles and methods underlying accelerated catalyst design and testing. The main challenges for progress in the field are also identified.

An indispensable book for all those working in catalytic process analysis and development, in industry and the academic laboratory. Contains an extensive review of catalytic principles, making the book also suitable for postgraduate students seeking to pursue a career in the catalysis field.

Content:
Front Matter....Pages I-XI
Front Matter....Pages 1-1
Challenges And Strategies for The Implementation of Combinatorial Methods and High Throughput Testing in Heterogeneous Catalysis....Pages 3-12
Problems and Challenges About Accelerated Testing of the Catalytic Activity of Catalysts....Pages 13-69
Mass Transfer Limitations: A Bottleneck for High Throughput Screening in Multiphase Catalysis....Pages 71-83
Combinatorial Methodology and its Experimental Validation by Parallel Synthesis, Testing and Characterization of Solid Catalytic Materials....Pages 85-100
The Combinatorial Approach for Heterogeneous Catalysis: A Challenge for Academic Research....Pages 101-124
An Evolutionary Strategy for The Design and Evaluation of High-Throughput Experiments....Pages 125-133
Organometallic Combinatorial Chemistry....Pages 135-151
Application Of Genetic Algorithms To The Development And Optimisation Of Light Paraffin Isomerisation Catalysts....Pages 153-172
Serial And Parallel Ways To Enhance And Accelerate Catalyst Testing....Pages 173-195
Rapid Catalyst Testing in The Boreskov Institute of Catalysis....Pages 197-215
Analysis and Modelling of Multi-Site Acid Catalysts....Pages 217-243
Combinatorial and High Throughput Approaches in Heterogeneous Catalysis: Reality or Illusion....Pages 245-256
Ultrafast Gas Chromatography....Pages 257-275
Front Matter....Pages 277-277
Parallel Catalytic Synthesis of Phosphines and Related Ligands....Pages 279-290
Mixed Oxide Catalysts For Oxidation of Propane to Acrylic Acid: A Method For The Preparation of Realistic Catalyst Libraries and Their Quantitative Assessment....Pages 291-297
High Throughput Testing of Catalysts for The Hydrogenation of Carbon Monoxide to Ethanol....Pages 299-303
Transformation of Short Chain N-Alkanes on Dodecatungstophosphoric Acid And Its Cesium Salts....Pages 305-308
Complete Catalytic Oxidation of Methane and Ethane Over Supported Platinum, Palladium and Manganese Oxide Catalysts....Pages 309-321
Rational Catalyst Selection and Optimization Versus Combinatorial? Case Study: Hydrogenolysys of Ethyl Laurate to 1-Dodecanol on Ru(Rh)-Sn(Re)/?-Al2O3 Catalysts....Pages 323-332
Studies on The Ultrasonic Enhancement of The Catalytic Activity in The Hydrogenation of Citral....Pages 333-335
Front Matter....Pages 277-277
Future Trends in The Worldwide oil Refining Industry....Pages 337-353
Catalyst Preparation and Testing for Catalytic Combustion of Chloromethanes....Pages 355-364
Impulse Oscillation Model For Accelerated Catalyst Design....Pages 365-374
Catalytic Oxidation of Binap on (Binap)Rh(Co)ci....Pages 375-381
Catalysts for Wastewater Treatment....Pages 383-388
The Routes of Deep Oxidation Reactions on The Cucl2/Al2O3 Catalysts in the Ethylene Oxychlorination Process.....Pages 389-397
The Catalytic Dehydrochlorination of Polychloroethanes in a Gas Phase....Pages 399-405
The Bimetallic Co-Containing Supported on Alumina Catalysts in the Synthesis on the Base of Carbon Oxides....Pages 407-415
Theoretical Investigations of Mo Catalysts in Olefin Metathesis....Pages 417-422
Differential Thermal Analysis and Thermal Gravimetry as Fast Methods to Test Catalytic Oxidation of Carbon Particulates....Pages 423-428
Aniline Methylation Over Modified Micro- And Mesoporous Catalysts....Pages 429-437
Live Catalysis....Pages 439-446
Front Matter....Pages 447-447
Accelerated Catalyst Preparation and Characterisation....Pages 449-467
Methods and Standards of Accelerated Catalyst Testing....Pages 469-479
Front Matter....Pages 481-481
Principles and Methods for Accelerated Catalyst Design, Preparation, Testing, and Development: Conclusions of the Nato Advanced Study Institute....Pages 483-489
Back Matter....Pages 491-521

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The pace of development in the chemical industry is increasing steadily, bringing with it a corresponding need to develop catalysts as rapidly as possible. High throughput experimentation has had great success in drug design but hitherto it has scarcely been used in the catalysis field. There is thus a need to make the underlying principles of this methodology more widely understood, in a coherent, integrated format. The present book fulfils such a need as it delineates and consolidates the principles and methods underlying accelerated catalyst design and testing. The main challenges for progress in the field are also identified.

An indispensable book for all those working in catalytic process analysis and development, in industry and the academic laboratory. Contains an extensive review of catalytic principles, making the book also suitable for postgraduate students seeking to pursue a career in the catalysis field.

Content:
Front Matter....Pages I-XI
Front Matter....Pages 1-1
Challenges And Strategies for The Implementation of Combinatorial Methods and High Throughput Testing in Heterogeneous Catalysis....Pages 3-12
Problems and Challenges About Accelerated Testing of the Catalytic Activity of Catalysts....Pages 13-69
Mass Transfer Limitations: A Bottleneck for High Throughput Screening in Multiphase Catalysis....Pages 71-83
Combinatorial Methodology and its Experimental Validation by Parallel Synthesis, Testing and Characterization of Solid Catalytic Materials....Pages 85-100
The Combinatorial Approach for Heterogeneous Catalysis: A Challenge for Academic Research....Pages 101-124
An Evolutionary Strategy for The Design and Evaluation of High-Throughput Experiments....Pages 125-133
Organometallic Combinatorial Chemistry....Pages 135-151
Application Of Genetic Algorithms To The Development And Optimisation Of Light Paraffin Isomerisation Catalysts....Pages 153-172
Serial And Parallel Ways To Enhance And Accelerate Catalyst Testing....Pages 173-195
Rapid Catalyst Testing in The Boreskov Institute of Catalysis....Pages 197-215
Analysis and Modelling of Multi-Site Acid Catalysts....Pages 217-243
Combinatorial and High Throughput Approaches in Heterogeneous Catalysis: Reality or Illusion....Pages 245-256
Ultrafast Gas Chromatography....Pages 257-275
Front Matter....Pages 277-277
Parallel Catalytic Synthesis of Phosphines and Related Ligands....Pages 279-290
Mixed Oxide Catalysts For Oxidation of Propane to Acrylic Acid: A Method For The Preparation of Realistic Catalyst Libraries and Their Quantitative Assessment....Pages 291-297
High Throughput Testing of Catalysts for The Hydrogenation of Carbon Monoxide to Ethanol....Pages 299-303
Transformation of Short Chain N-Alkanes on Dodecatungstophosphoric Acid And Its Cesium Salts....Pages 305-308
Complete Catalytic Oxidation of Methane and Ethane Over Supported Platinum, Palladium and Manganese Oxide Catalysts....Pages 309-321
Rational Catalyst Selection and Optimization Versus Combinatorial? Case Study: Hydrogenolysys of Ethyl Laurate to 1-Dodecanol on Ru(Rh)-Sn(Re)/?-Al2O3 Catalysts....Pages 323-332
Studies on The Ultrasonic Enhancement of The Catalytic Activity in The Hydrogenation of Citral....Pages 333-335
Front Matter....Pages 277-277
Future Trends in The Worldwide oil Refining Industry....Pages 337-353
Catalyst Preparation and Testing for Catalytic Combustion of Chloromethanes....Pages 355-364
Impulse Oscillation Model For Accelerated Catalyst Design....Pages 365-374
Catalytic Oxidation of Binap on (Binap)Rh(Co)ci....Pages 375-381
Catalysts for Wastewater Treatment....Pages 383-388
The Routes of Deep Oxidation Reactions on The Cucl2/Al2O3 Catalysts in the Ethylene Oxychlorination Process.....Pages 389-397
The Catalytic Dehydrochlorination of Polychloroethanes in a Gas Phase....Pages 399-405
The Bimetallic Co-Containing Supported on Alumina Catalysts in the Synthesis on the Base of Carbon Oxides....Pages 407-415
Theoretical Investigations of Mo Catalysts in Olefin Metathesis....Pages 417-422
Differential Thermal Analysis and Thermal Gravimetry as Fast Methods to Test Catalytic Oxidation of Carbon Particulates....Pages 423-428
Aniline Methylation Over Modified Micro- And Mesoporous Catalysts....Pages 429-437
Live Catalysis....Pages 439-446
Front Matter....Pages 447-447
Accelerated Catalyst Preparation and Characterisation....Pages 449-467
Methods and Standards of Accelerated Catalyst Testing....Pages 469-479
Front Matter....Pages 481-481
Principles and Methods for Accelerated Catalyst Design, Preparation, Testing, and Development: Conclusions of the Nato Advanced Study Institute....Pages 483-489
Back Matter....Pages 491-521
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