Ebook: Modern Techniques in Protein NMR
- Tags: Imaging / Radiology, Biochemistry general, Biophysics/Biomedical Physics, Atoms Molecules Clusters and Plasmas, Physical Chemistry
- Series: Biological Magnetic Resonance 16
- Year: 2002
- Publisher: Springer US
- Edition: 1
- Language: English
- pdf
Volume 16 marks the beginning of a special topic series devoted to modern techniques in protein NMR, under the Biological Magnetic Resonance series. This volume is being followed by Volume 17 with the subtitle Structure Computation and Dynamics in Protein NMR. Volumes 16 and 17 present some of the recent, significant advances in biomolecular NMR field with emphasis on developments during the last five years. We are honored to have brought together in these volumes some of the world’s foremost experts who have provided broad leadership in advancing this field. Volume 16 contains advances in two broad categories: the first, Large Proteins, Complexes, and Membrane Proteins, and second, Pulse Methods. Volume 17, which will follow covers major advances in Computational Methods, and Structure and Dynamics. In the opening chapter of Volume 16, Marius Clore and Angela Gronenborn give a brief review of NMR strategies including the use of long range restraints in the structure determination of large proteins and protein complexes. In the next two chapters, Lewis Kay and Ron Venters and their collaborators describe state-of-t- art advances in the study of perdeuterated large proteins. They are followed by Stanley Opella and co-workers who present recent developments in the study of membrane proteins. (A related topic dealing with magnetic field induced residual dipolar couplings in proteins will appear in the section on Structure and Dynamics in Volume 17).
Volume 16 of Biological Magnetic Resonance (Modern Techniques inProtein NMR) represents significant advances in the biomolecular NMR field, with emphasis on developments during the recent years. This book brings together some of the world's foremost experts who have provided broad leadership in advancing the field.
Volume 16 is devoted to topics on biomacromolecules and pulse methods. It covers advances in the study of large proteins and protein complexes, methods involving perdeuterated large proteins, membrane proteins, advances in pulse schemes for spin decoupling and for the measurement of coupling constants and torsion angle constraints including cross-correlated relaxation spectroscopy.
Volume 16 of Biological Magnetic Resonance (Modern Techniques inProtein NMR) represents significant advances in the biomolecular NMR field, with emphasis on developments during the recent years. This book brings together some of the world's foremost experts who have provided broad leadership in advancing the field.
Volume 16 is devoted to topics on biomacromolecules and pulse methods. It covers advances in the study of large proteins and protein complexes, methods involving perdeuterated large proteins, membrane proteins, advances in pulse schemes for spin decoupling and for the measurement of coupling constants and torsion angle constraints including cross-correlated relaxation spectroscopy.
Content:
Front Matter....Pages i-xvi
Front Matter....Pages 1-1
Determining Structures of Large Proteins and Protein Complexes by NMR....Pages 3-26
Multidimensional 2H-Based NMR Methods for Resonance Assignment, Structure Determination, and The Study of Protein Dynamics....Pages 27-74
NMR of Perdeuterated Large Proteins....Pages 75-120
Recent Developments in Multidimensional NMR Methods for Structural Studies of Membrane Proteins....Pages 121-145
Front Matter....Pages 147-147
Homonuclear Decoupling in Proteins....Pages 149-193
Pulse Sequences for Measuring Coupling Constants....Pages 195-257
Methods for the Determination of Torsion Angle Restraints in Biomacromolecules....Pages 259-367
Back Matter....Pages 369-387
Volume 16 of Biological Magnetic Resonance (Modern Techniques inProtein NMR) represents significant advances in the biomolecular NMR field, with emphasis on developments during the recent years. This book brings together some of the world's foremost experts who have provided broad leadership in advancing the field.
Volume 16 is devoted to topics on biomacromolecules and pulse methods. It covers advances in the study of large proteins and protein complexes, methods involving perdeuterated large proteins, membrane proteins, advances in pulse schemes for spin decoupling and for the measurement of coupling constants and torsion angle constraints including cross-correlated relaxation spectroscopy.
Content:
Front Matter....Pages i-xvi
Front Matter....Pages 1-1
Determining Structures of Large Proteins and Protein Complexes by NMR....Pages 3-26
Multidimensional 2H-Based NMR Methods for Resonance Assignment, Structure Determination, and The Study of Protein Dynamics....Pages 27-74
NMR of Perdeuterated Large Proteins....Pages 75-120
Recent Developments in Multidimensional NMR Methods for Structural Studies of Membrane Proteins....Pages 121-145
Front Matter....Pages 147-147
Homonuclear Decoupling in Proteins....Pages 149-193
Pulse Sequences for Measuring Coupling Constants....Pages 195-257
Methods for the Determination of Torsion Angle Restraints in Biomacromolecules....Pages 259-367
Back Matter....Pages 369-387
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