Ebook: Molecular Interactions of Actin: Actin-Myosin Interaction and Actin-Based Regulation

Actin is one of the most widespread proteins in eukaryotic cells. This book and its companion (Molecular Interactions of Actin. Actin Structure and Actin-Binding Proteins) provide an authoritative and opinionated view of the structure and function of this essential protein. Each section includes an historical perspective and a detailed commentary on actin protein chemistry, molecular and cell biology of actin. While some chapters review the body of knowledge of the subject, others contain new experimental data.
This book will appeal to research scientists seeking contemporary overviews of actin-myosin interaction and actin-based regulation. Contributors include senior scientists as well as the new breed of younger scientists.

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Actin is one of the most widespread proteins in eukaryotic cells. This book and its companion (Molecular Interactions of Actin. Actin Structure and Actin-Binding Proteins) provide an authoritative and opinionated view of the structure and function of this essential protein. Each section includes an historical perspective and a detailed commentary on actin protein chemistry, molecular and cell biology of actin. While some chapters review the body of knowledge of the subject, others contain new experimental data.
This book will appeal to research scientists seeking contemporary overviews of actin-myosin interaction and actin-based regulation. Contributors include senior scientists as well as the new breed of younger scientists.

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Actin is one of the most widespread proteins in eukaryotic cells. This book and its companion (Molecular Interactions of Actin. Actin Structure and Actin-Binding Proteins) provide an authoritative and opinionated view of the structure and function of this essential protein. Each section includes an historical perspective and a detailed commentary on actin protein chemistry, molecular and cell biology of actin. While some chapters review the body of knowledge of the subject, others contain new experimental data.
This book will appeal to research scientists seeking contemporary overviews of actin-myosin interaction and actin-based regulation. Contributors include senior scientists as well as the new breed of younger scientists.
Content:
Front Matter....Pages I-XII
An Overview of the Actin-Myosin Interaction....Pages 1-5
Changes in Actin and Myosin Structural Dynamics Due to Their Weak and Strong Interactions....Pages 7-19
Fluorescence Resonance Energy Transfer in Acto-Myosin Complexes....Pages 21-30
Insights into Actomyosin Interactions from Actin Mutations....Pages 31-49
Role of Charges in Actomyosin Interactions....Pages 51-64
The Alanine-Scanning Mutagenesis of Dictyostelium Myosin II at the Ionic Interface with Actin....Pages 65-74
Familial Hypertrophic Cardiomyopathic Myosin Mutations That Affect the Actin-Myosin Interaction....Pages 75-86
Coupling Between Chemical and Mechanical Events and Conformation of Single Protein Molecules....Pages 87-105
An Overview of Actin-Based Calcium Regulation....Pages 107-109
Cooperativity in the Ca2+ Regulation of Muscle Contraction....Pages 111-132
Motility Assays of Calcium Regulation of Actin Filaments....Pages 133-148
The Ultrastructural Basis of Actin Filament Regulation....Pages 149-169
The Role of Troponin in the Ca2+-Regulation of Skeletal Muscle Contraction....Pages 171-190
Structural Changes Between Regulatory Proteins and Actin: A Regulation Model by Tropomyosin-Troponin Based on FRET Measurements....Pages 191-203
Back Matter....Pages 205-207

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Actin is one of the most widespread proteins in eukaryotic cells. This book and its companion (Molecular Interactions of Actin. Actin Structure and Actin-Binding Proteins) provide an authoritative and opinionated view of the structure and function of this essential protein. Each section includes an historical perspective and a detailed commentary on actin protein chemistry, molecular and cell biology of actin. While some chapters review the body of knowledge of the subject, others contain new experimental data.
This book will appeal to research scientists seeking contemporary overviews of actin-myosin interaction and actin-based regulation. Contributors include senior scientists as well as the new breed of younger scientists.
Content:
Front Matter....Pages I-XII
An Overview of the Actin-Myosin Interaction....Pages 1-5
Changes in Actin and Myosin Structural Dynamics Due to Their Weak and Strong Interactions....Pages 7-19
Fluorescence Resonance Energy Transfer in Acto-Myosin Complexes....Pages 21-30
Insights into Actomyosin Interactions from Actin Mutations....Pages 31-49
Role of Charges in Actomyosin Interactions....Pages 51-64
The Alanine-Scanning Mutagenesis of Dictyostelium Myosin II at the Ionic Interface with Actin....Pages 65-74
Familial Hypertrophic Cardiomyopathic Myosin Mutations That Affect the Actin-Myosin Interaction....Pages 75-86
Coupling Between Chemical and Mechanical Events and Conformation of Single Protein Molecules....Pages 87-105
An Overview of Actin-Based Calcium Regulation....Pages 107-109
Cooperativity in the Ca2+ Regulation of Muscle Contraction....Pages 111-132
Motility Assays of Calcium Regulation of Actin Filaments....Pages 133-148
The Ultrastructural Basis of Actin Filament Regulation....Pages 149-169
The Role of Troponin in the Ca2+-Regulation of Skeletal Muscle Contraction....Pages 171-190
Structural Changes Between Regulatory Proteins and Actin: A Regulation Model by Tropomyosin-Troponin Based on FRET Measurements....Pages 191-203
Back Matter....Pages 205-207
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