Ebook: Ribosomes

Dr. Spirin is a world authority on ribosomes and has published two earlier books in this area in English.
This text is for advanced undergraduates and beginning graduate students and will cover the structure, function, and biosynthesis of ribosomes. Ribosomes are important in protein synthesis, which is currently a hot topic in many different areas of research.

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Dr. Spirin is a world authority on ribosomes and has published two earlier books in this area in English.
This text is for advanced undergraduates and beginning graduate students and will cover the structure, function, and biosynthesis of ribosomes. Ribosomes are important in protein synthesis, which is currently a hot topic in many different areas of research.
Content:
Front Matter....Pages i-xv
Protein Biosynthesis....Pages 3-5
Messenger RNA and the Genetic Code....Pages 7-22
Transfer RNA and Aminoacyl-tRNA Synthetases....Pages 23-45
Ribosomes and Translation....Pages 47-60
Morphology of the Ribosome....Pages 63-73
Ribosomal RNA....Pages 75-95
Ribosomal Proteins....Pages 97-116
Mutual Arrangement of Ribosomal RNA and Proteins (Quaternary Structure)....Pages 117-129
Functional Activities and Functional Sites of the Ribosome....Pages 133-161
Elongation Cycle, Step I: Aminoacyl-tRNA Binding....Pages 163-193
Elongation Cycle, Step II: Transpeptidation (Peptide Bond Formation)....Pages 195-211
Elongation Cycle, Step III: Translocation....Pages 213-239
Elongation Rates and its Modulation....Pages 241-259
Termination of Translation....Pages 261-270
Initiation of Translation....Pages 271-308
Translational Control in Prokaryotes....Pages 309-338
Translational Control in Eukaryotes....Pages 339-369
Cotranslational Folding and Transmembrane Transport of Proteins....Pages 371-396
Conclusion: General Principles of Ribosome Structure and Function....Pages 397-405
Back Matter....Pages 407-416

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Dr. Spirin is a world authority on ribosomes and has published two earlier books in this area in English.
This text is for advanced undergraduates and beginning graduate students and will cover the structure, function, and biosynthesis of ribosomes. Ribosomes are important in protein synthesis, which is currently a hot topic in many different areas of research.
Content:
Front Matter....Pages i-xv
Protein Biosynthesis....Pages 3-5
Messenger RNA and the Genetic Code....Pages 7-22
Transfer RNA and Aminoacyl-tRNA Synthetases....Pages 23-45
Ribosomes and Translation....Pages 47-60
Morphology of the Ribosome....Pages 63-73
Ribosomal RNA....Pages 75-95
Ribosomal Proteins....Pages 97-116
Mutual Arrangement of Ribosomal RNA and Proteins (Quaternary Structure)....Pages 117-129
Functional Activities and Functional Sites of the Ribosome....Pages 133-161
Elongation Cycle, Step I: Aminoacyl-tRNA Binding....Pages 163-193
Elongation Cycle, Step II: Transpeptidation (Peptide Bond Formation)....Pages 195-211
Elongation Cycle, Step III: Translocation....Pages 213-239
Elongation Rates and its Modulation....Pages 241-259
Termination of Translation....Pages 261-270
Initiation of Translation....Pages 271-308
Translational Control in Prokaryotes....Pages 309-338
Translational Control in Eukaryotes....Pages 339-369
Cotranslational Folding and Transmembrane Transport of Proteins....Pages 371-396
Conclusion: General Principles of Ribosome Structure and Function....Pages 397-405
Back Matter....Pages 407-416
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