Ebook: Principles of Protein X-ray Crystallography

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Content:
Front Matter....Pages i-xv
Crystallizing a Protein....Pages 1-21
X-ray Sources and Detectors....Pages 22-49
Crystals....Pages 50-69
The Theory of X-ray Diffraction by a Crystal....Pages 70-116
Average Reflection Intensity and Distribution of Structure Factor Data....Pages 117-124
Special Forms of the Structure Factor....Pages 125-128
The Solution of the Phase Problem by the Isomorphous Replacement Method....Pages 129-179
Phase Improvement....Pages 180-202
Anomalous Scattering in the Determination of the Protein Phase Angles and the Absolute Configuration....Pages 203-218
Molecular Replacement....Pages 219-243
Direct Methods....Pages 244-252
Laue Diffraction....Pages 253-259
Refinement of the Model Structure....Pages 260-291
The Combination of Phase Information....Pages 292-297
Checking for Gross Errors and Estimating the Accuracy of the Structural Model....Pages 298-310
Back Matter....Pages 311-341

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Content:
Front Matter....Pages i-xv
Crystallizing a Protein....Pages 1-21
X-ray Sources and Detectors....Pages 22-49
Crystals....Pages 50-69
The Theory of X-ray Diffraction by a Crystal....Pages 70-116
Average Reflection Intensity and Distribution of Structure Factor Data....Pages 117-124
Special Forms of the Structure Factor....Pages 125-128
The Solution of the Phase Problem by the Isomorphous Replacement Method....Pages 129-179
Phase Improvement....Pages 180-202
Anomalous Scattering in the Determination of the Protein Phase Angles and the Absolute Configuration....Pages 203-218
Molecular Replacement....Pages 219-243
Direct Methods....Pages 244-252
Laue Diffraction....Pages 253-259
Refinement of the Model Structure....Pages 260-291
The Combination of Phase Information....Pages 292-297
Checking for Gross Errors and Estimating the Accuracy of the Structural Model....Pages 298-310
Back Matter....Pages 311-341
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