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This volume describes an impressive array of the current photonic-related technologies being used in the investigation of biological systems. The topics include various types of microscopy (fluorescence correlation microscopy, two-photon microscopy), sensitive detection of biological molecules, nano-surgery techniques, fluorescence resonance energy transfer, nano-plasmonics, terahertz spectroscopy, and photosynthetic energy conversion. The emphasis is on the physical principles behind each technique, and on examining the advantages and limitations of each.The book begins with an overview by Paras Prasad, a leader in the field of biophotonics, of several important optical techniques currently used for studying biological systems. In the subsequent chapters these techniques are discussed in depth, providing the reader with a detailed understanding of the basic physical principles at work. An excellent treatment of terahertz spectroscopy demonstrates how photonics is being extended beyond the visible region. Recent results in the use of femtosecond lasers as a tool to porate cell walls demonstrate that the manipulation of light can be used as a tool for the study and the treatment of biological systems. The field of Bio-photonics is broad and still growing, so cannot be covered comprehensively in one volume. But here the reader will find an introduction to some of the major tools used for studying biological systems, and at the same time a detailed, first-principles treatment of the physics behind these tools.




This volume describes an impressive array of the current photonic-related technologies being used in the investigation of biological systems. The topics include various types of microscopy (fluorescence correlation microscopy, two-photon microscopy), sensitive detection of biological molecules, nano-surgery techniques, fluorescence resonance energy transfer, nano-plasmonics, terahertz spectroscopy, and photosynthetic energy conversion. The emphasis is on the physical principles behind each technique, and on examining the advantages and limitations of each.The book begins with an overview by Paras Prasad, a leader in the field of biophotonics, of several important optical techniques currently used for studying biological systems. In the subsequent chapters these techniques are discussed in depth, providing the reader with a detailed understanding of the basic physical principles at work. An excellent treatment of terahertz spectroscopy demonstrates how photonics is being extended beyond the visible region. Recent results in the use of femtosecond lasers as a tool to porate cell walls demonstrate that the manipulation of light can be used as a tool for the study and the treatment of biological systems. The field of Bio-photonics is broad and still growing, so cannot be covered comprehensively in one volume. But here the reader will find an introduction to some of the major tools used for studying biological systems, and at the same time a detailed, first-principles treatment of the physics behind these tools.


This volume describes an impressive array of the current photonic-related technologies being used in the investigation of biological systems. The topics include various types of microscopy (fluorescence correlation microscopy, two-photon microscopy), sensitive detection of biological molecules, nano-surgery techniques, fluorescence resonance energy transfer, nano-plasmonics, terahertz spectroscopy, and photosynthetic energy conversion. The emphasis is on the physical principles behind each technique, and on examining the advantages and limitations of each.The book begins with an overview by Paras Prasad, a leader in the field of biophotonics, of several important optical techniques currently used for studying biological systems. In the subsequent chapters these techniques are discussed in depth, providing the reader with a detailed understanding of the basic physical principles at work. An excellent treatment of terahertz spectroscopy demonstrates how photonics is being extended beyond the visible region. Recent results in the use of femtosecond lasers as a tool to porate cell walls demonstrate that the manipulation of light can be used as a tool for the study and the treatment of biological systems. The field of Bio-photonics is broad and still growing, so cannot be covered comprehensively in one volume. But here the reader will find an introduction to some of the major tools used for studying biological systems, and at the same time a detailed, first-principles treatment of the physics behind these tools.
Content:
Front Matter....Pages i-xv
Front Matter....Pages 1-1
Biophotonics: Harnessing Light for Biology and Medicine....Pages 3-17
Nano-Plasmonics for Bio-Photonics....Pages 19-23
Photons and Photon Correlation Spectroscopy....Pages 25-62
Principles and Applications of Fluorescence Correlation Spectroscopy (FCS)....Pages 63-85
Nanoscopy Using Localization and Temporal Separation of Fluorescence From Single Molecules....Pages 87-106
Fluorescence Spectroscopy and Energy Transfer Processes in Biological Systems....Pages 107-171
Fluorescence of Strongly Absorbing Multicomponent Media....Pages 173-181
Coherent Quantum Control in Biological Systems....Pages 183-201
Subcellular Surgery and Nanoneurosurgery Using Femtosecond Laser Pulses....Pages 203-218
Solar Energy Conversion – Natural to Artificial....Pages 219-236
Whispering Gallery Mode Biosensor....Pages 237-259
Two-Photon Absorption and Applications to Biological Systems....Pages 261-285
Terahertz Spectroscopy of Biological Systems....Pages 287-303
Laser-Produced Plasmas for Bio-Photonics....Pages 305-319
Real-Time Spectroscopy of Solid-State Random Lasers....Pages 321-342
Front Matter....Pages 343-343
Neutrinos in Particle Physics and Astrophysics....Pages 345-356
Front Matter....Pages 357-357
Persistent Hole Burning Induced by Resonant Energy Migration....Pages 359-360
The Biophotonics Group @ “Naples-1” University....Pages 361-361
Spectroscopy of Individual “Artificial Atoms”....Pages 363-363
Spontaneous Light Emission from Alive Cotton Cell-Hair....Pages 365-365
Front Matter....Pages 357-357
Mesoscopic Spectral Modulation of Light Transmitted by a Subwavelength Aperture....Pages 367-367
Optical and Vibrational Characterization of Nanostructured Semiconductor Materials....Pages 369-369
Defects in the Atp2b2 Gene Causing Hereditary Hearing and Balance Loss in Mice and Humans: A Biophysical Study of Normal and Mutated PMCA2 Pump Function....Pages 371-371
On the Way to Study the Uptake Mechanisms of Cell Penetrating Peptoids by Single-Molecule Methods....Pages 373-373
Hybrid Solar Cells....Pages 375-375
Bio-Electromagnetics: Microwave Radar System for Breast Cancer Detection....Pages 377-377
Nanocrystal Quantum Dots for Quantum Information Processing....Pages 379-379
Solvation Dynamics Using Ultrafast X-Ray Absorption Spectroscopy....Pages 381-381
Development of Optical Biosensors on Basis of Micro-Disk Resonators....Pages 383-383
Multiple Trap Optical Tweezers for Live Cell Force Measurements....Pages 385-386
Heterodyne Interferometric Polarization-Sensitive Coherent Anti-Stokes Raman Scattering (HIP-CARS) Spectroscopy....Pages 387-388
From Curved Space to Optical Cloaking....Pages 389-389
Front Matter....Pages 391-391
(Zn,Cu)O Photocatalytic Material and Znga2o4: Eu3+ Phosphors....Pages 393-394
Integrated Waveguide Probes as Alternatives to Fiber-Optic Probes for Backscattering and Fluorescence Measurements....Pages 395-396
Characterization of Nanoporous Ceramic Materials Using Combined XRD, XPS and PAL Spectroscopy....Pages 397-397
Femtosecond Laser Surgery: From the Tissue to the Cells....Pages 399-400
Fluorescence Spectroscopy of Crystalline Conformational Changes Under UV-Radiation....Pages 401-401
Incorporation of Axially Substituted Monophtalocyanines of Zirconium, Hafnium and Selected Lanthanides in Monolithic Silica Blocks and Their Optical Properties....Pages 403-403
Design of the Unequal Multilayer Structures for the Selective Optical Filters....Pages 405-405
Optical Properties, Morphology and Long Time Degradation of alq3 Thin Films....Pages 407-407
Front Matter....Pages 391-391
Triplet–Triplet Energy Transfer in Nanodimensional Molecular Layers....Pages 409-410
The Influence of Driving Force on Formation and Geminate Recombination of Charges in Alternating Polyfluorene Copolymer/Fullerene Blends....Pages 411-412
(Sub)Picosecond Dynamics in MgDNA Complexes Upon Lowering the PH: A Raman Microspectroscopic Study....Pages 413-413
One- and Two-Photon Pumped DFB Laser Based on Semiconductor Quantum Dots Embedded in a Sol-Gel Matrix....Pages 415-416
NATO ASI 983377 Biophotonics Spectroscopy, Imaging, Sensing and Manipulation....Pages 417-429
Back Matter....Pages 431-433


This volume describes an impressive array of the current photonic-related technologies being used in the investigation of biological systems. The topics include various types of microscopy (fluorescence correlation microscopy, two-photon microscopy), sensitive detection of biological molecules, nano-surgery techniques, fluorescence resonance energy transfer, nano-plasmonics, terahertz spectroscopy, and photosynthetic energy conversion. The emphasis is on the physical principles behind each technique, and on examining the advantages and limitations of each.The book begins with an overview by Paras Prasad, a leader in the field of biophotonics, of several important optical techniques currently used for studying biological systems. In the subsequent chapters these techniques are discussed in depth, providing the reader with a detailed understanding of the basic physical principles at work. An excellent treatment of terahertz spectroscopy demonstrates how photonics is being extended beyond the visible region. Recent results in the use of femtosecond lasers as a tool to porate cell walls demonstrate that the manipulation of light can be used as a tool for the study and the treatment of biological systems. The field of Bio-photonics is broad and still growing, so cannot be covered comprehensively in one volume. But here the reader will find an introduction to some of the major tools used for studying biological systems, and at the same time a detailed, first-principles treatment of the physics behind these tools.
Content:
Front Matter....Pages i-xv
Front Matter....Pages 1-1
Biophotonics: Harnessing Light for Biology and Medicine....Pages 3-17
Nano-Plasmonics for Bio-Photonics....Pages 19-23
Photons and Photon Correlation Spectroscopy....Pages 25-62
Principles and Applications of Fluorescence Correlation Spectroscopy (FCS)....Pages 63-85
Nanoscopy Using Localization and Temporal Separation of Fluorescence From Single Molecules....Pages 87-106
Fluorescence Spectroscopy and Energy Transfer Processes in Biological Systems....Pages 107-171
Fluorescence of Strongly Absorbing Multicomponent Media....Pages 173-181
Coherent Quantum Control in Biological Systems....Pages 183-201
Subcellular Surgery and Nanoneurosurgery Using Femtosecond Laser Pulses....Pages 203-218
Solar Energy Conversion – Natural to Artificial....Pages 219-236
Whispering Gallery Mode Biosensor....Pages 237-259
Two-Photon Absorption and Applications to Biological Systems....Pages 261-285
Terahertz Spectroscopy of Biological Systems....Pages 287-303
Laser-Produced Plasmas for Bio-Photonics....Pages 305-319
Real-Time Spectroscopy of Solid-State Random Lasers....Pages 321-342
Front Matter....Pages 343-343
Neutrinos in Particle Physics and Astrophysics....Pages 345-356
Front Matter....Pages 357-357
Persistent Hole Burning Induced by Resonant Energy Migration....Pages 359-360
The Biophotonics Group @ “Naples-1” University....Pages 361-361
Spectroscopy of Individual “Artificial Atoms”....Pages 363-363
Spontaneous Light Emission from Alive Cotton Cell-Hair....Pages 365-365
Front Matter....Pages 357-357
Mesoscopic Spectral Modulation of Light Transmitted by a Subwavelength Aperture....Pages 367-367
Optical and Vibrational Characterization of Nanostructured Semiconductor Materials....Pages 369-369
Defects in the Atp2b2 Gene Causing Hereditary Hearing and Balance Loss in Mice and Humans: A Biophysical Study of Normal and Mutated PMCA2 Pump Function....Pages 371-371
On the Way to Study the Uptake Mechanisms of Cell Penetrating Peptoids by Single-Molecule Methods....Pages 373-373
Hybrid Solar Cells....Pages 375-375
Bio-Electromagnetics: Microwave Radar System for Breast Cancer Detection....Pages 377-377
Nanocrystal Quantum Dots for Quantum Information Processing....Pages 379-379
Solvation Dynamics Using Ultrafast X-Ray Absorption Spectroscopy....Pages 381-381
Development of Optical Biosensors on Basis of Micro-Disk Resonators....Pages 383-383
Multiple Trap Optical Tweezers for Live Cell Force Measurements....Pages 385-386
Heterodyne Interferometric Polarization-Sensitive Coherent Anti-Stokes Raman Scattering (HIP-CARS) Spectroscopy....Pages 387-388
From Curved Space to Optical Cloaking....Pages 389-389
Front Matter....Pages 391-391
(Zn,Cu)O Photocatalytic Material and Znga2o4: Eu3+ Phosphors....Pages 393-394
Integrated Waveguide Probes as Alternatives to Fiber-Optic Probes for Backscattering and Fluorescence Measurements....Pages 395-396
Characterization of Nanoporous Ceramic Materials Using Combined XRD, XPS and PAL Spectroscopy....Pages 397-397
Femtosecond Laser Surgery: From the Tissue to the Cells....Pages 399-400
Fluorescence Spectroscopy of Crystalline Conformational Changes Under UV-Radiation....Pages 401-401
Incorporation of Axially Substituted Monophtalocyanines of Zirconium, Hafnium and Selected Lanthanides in Monolithic Silica Blocks and Their Optical Properties....Pages 403-403
Design of the Unequal Multilayer Structures for the Selective Optical Filters....Pages 405-405
Optical Properties, Morphology and Long Time Degradation of alq3 Thin Films....Pages 407-407
Front Matter....Pages 391-391
Triplet–Triplet Energy Transfer in Nanodimensional Molecular Layers....Pages 409-410
The Influence of Driving Force on Formation and Geminate Recombination of Charges in Alternating Polyfluorene Copolymer/Fullerene Blends....Pages 411-412
(Sub)Picosecond Dynamics in MgDNA Complexes Upon Lowering the PH: A Raman Microspectroscopic Study....Pages 413-413
One- and Two-Photon Pumped DFB Laser Based on Semiconductor Quantum Dots Embedded in a Sol-Gel Matrix....Pages 415-416
NATO ASI 983377 Biophotonics Spectroscopy, Imaging, Sensing and Manipulation....Pages 417-429
Back Matter....Pages 431-433
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