Ebook: Interface Oral Health Science 2009

Since 2002, the Tohoku University Graduate School of Dentistry has proposed “Interface Oral Health Science” as a major theme for next-generation dental research. That theme is based on the following new concept: healthy oral fu- tion is maintained by biological and biomechanical harmony among three s- tems: (1) oral tissues (host); (2) parasitic microorganisms of the oral cavity (parasites); and (3) biomaterials. The concept implies that oral diseases such as dental caries, periodontal disease, and temporomandibular disorders should be interpreted as “interface disorders” that result from disruption of the intact int- face among these systems. The uniqueness of this concept rests on the fact that it not only encompasses the field of dentistry and dental medicine, but also expands the common ground shared with other fields, including medicine, ag- culture, material science, engineering, and pharmacology. We aim to promote advances in dental research and to activate collaboration with related fields by putting interface oral health science into practice. On this basis, we have already organized the 1st and 2nd International Symposiums for Interface Oral Health Science, which included inspiring special lectures, symposiums, poster pres- tations, and other discussions. The contents of the two symposiums were p- lished as monographs entitled Interface Oral Health Science in 2005 and 2007. The 3rd International Symposium was held in January 2009 as part of this project.

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The Tohoku University Graduate School of Dentistry has proposed Interface Oral Health Science as the main theme of next-generation dental research since 2002. That theme is based on the new concept that healthy oral function is provided by biological and biomechanical harmony among three systems: oral tissues, parasites, and biomaterials, and that oral diseases are interpreted as "interface diseases" caused by disruption of the intact interfaces among those systems.

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The Tohoku University Graduate School of Dentistry has proposed Interface Oral Health Science as the main theme of next-generation dental research since 2002. That theme is based on the new concept that healthy oral function is provided by biological and biomechanical harmony among three systems: oral tissues, parasites, and biomaterials, and that oral diseases are interpreted as "interface diseases" caused by disruption of the intact interfaces among those systems.

Content:
Front Matter....Pages i-xxiii
Front Matter....Pages 1-1
Shear-stress-sensing and response mechanisms in vascular endothelial cells....Pages 3-9
Front Matter....Pages 12-12
Cleft formation and branching morphogenesis of salivary gland: exploration of new functional genes....Pages 13-19
Strategies underlying research in tooth regenerative therapy as a possible model for future organ replacement....Pages 20-26
Molecular basis for specification of the vertebrate head field....Pages 27-32
Dental epithelium proliferation and differentiation regulated by ameloblastin....Pages 33-38
Front Matter....Pages 40-40
Stress fiber and the mechanical states in a living endothelial cell....Pages 41-47
Transient receptor potential channels and mechanobiology....Pages 48-52
Molecular mechanisms of the response to mechanical stimulation during chondrocyte differentiation....Pages 53-59
Recruitment of masseter motoneurons by spindle Ia inputs and its modulation by leak K+ channels....Pages 60-65
Front Matter....Pages 68-68
Implant interface to bone tissue: biomimetic surface functionalization through nanotechnology....Pages 69-75
Interface affinity between apatites and biological tissues....Pages 76-82
Biological reactions on titanium surface electrodeposited biofunctional molecules....Pages 83-89
Effect of Young’s modulus in metallic implants on atrophy and bone remodeling....Pages 90-99
Chemical and physical factors affecting osteoconductivity of octacalcium phosphate bone substitute material....Pages 100-107
Front Matter....Pages 110-110
Effects of zebularine on the apoptosis of 5-fluorouracil via cAMP/PKA/CREB pathway in HSC-3 cells....Pages 111-112
Wnt signaling inhibits cementoblast differentiation....Pages 113-115
Prevention of necrotic actions of nitrogen-containing bisphosphonates (NBPs) in mice by non-NBPs (clodronate and etidronate)....Pages 116-118
Interface, implant, regenerated bone and recipient alveolar bone....Pages 119-122
Activation of matrix metalloproteinase-2 at the interface between epithelial cells and fibroblasts from human periodontal ligament....Pages 123-125
Histomorphometric study of alveolar bone-implant (miniscrew) interface used as an orthodontic anchorage....Pages 126-128
Front Matter....Pages 110-110
Mechanical stress modulates bone remodeling signals....Pages 129-132
Expression analysis of p51/p63 in enamel organ epithelial cells....Pages 133-135
Osteogenesis by gradually expanding the interface between bone surface and periosteum: preliminary analysis of the use of novel plate and bone marrow stem cell administration in rabbits....Pages 136-137
Possible role of Ccn family members during osteoblast differentiation....Pages 138-139
Inhibition of oral fibroblast growth and function by N-acetyl cysteine....Pages 140-142
Computer simulation of orthodontic tooth movement using FE analysis....Pages 143-144
Mechanical-stress-induced apoptosis and angiogenesis in periodontal tissue....Pages 145-147
Diachronic changes of tooth wear in the deciduous dentition of the Japanese....Pages 148-149
Dental occlusal deformation analysis of porcine mandibular periodontium using digital image correlation method....Pages 150-152
Measurement of the transmitted-light through human upper incisors....Pages 153-154
Three-dimensional finite element analysis of overload-induced alveolar bone resorption around dental implants....Pages 155-157
Regulation of microrna expression by bone morphogenetic protein-2....Pages 158-160
Influence of early progressive loading on implants placed into extraction sockets....Pages 161-162
In vitro gene transfection of human stromal cell derived factor-1? and its expression in rat myoblasts....Pages 163-166
Biomarker identification in oral cancer by using proteomics....Pages 167-168
In vivo analysis of the 3-D force on implants supporting fixed prostheses....Pages 169-171
Gap junctional communication regulates salivary gland morphogenesis....Pages 172-173
Pulpal blood flow in human permanent teeth with different root formation....Pages 174-176
Immunohistological study on stro-1 in developing rat dental tissues with light and electron microscopy....Pages 177-178
The physiological calcification process is replicated in a rat embryonic calvarial culture....Pages 179-180
Front Matter....Pages 110-110
Tonometric measurement of the gingiva in young and elder humans....Pages 181-183
Isolation and comparison of mesenchymal stem cells derived from human wisdom tooth germs and periodontal ligament in vitro....Pages 184-186
Unitary discharges of TMJ mechanosensitive neurons during cortically induced jaw movement....Pages 187-189
Evaluation of bone metabolism of temporomandibular joint by using high resolution PET scanner....Pages 190-192
Physiological role of type II bone morphogenetic protein receptor and its interacting molecules in bone morphogenetic protein signaling....Pages 193-195
Role of the protein serine/threonine phosphatase dullard in cell differentiation....Pages 196-198
The role of extracellular signal-regulated kinase 5 signaling pathway in neurons....Pages 199-201
Regulation of bone morphogenetic protein-mediated signaling by tumor necrosis factor-?....Pages 202-204
Mechanosensitive TRP channels in osteoblasts....Pages 205-206
Immunohistochemical localization of CD134 ligand, CD137 ligand, GITR ligand, and BAFF in Sj?gren’s syndrome-like autoimmune sialadenitis of MRL/lpr mice....Pages 207-209
Expression of microrna during tooth development....Pages 210-211
Front Matter....Pages 214-214
New quantitative fluorometry for evaluating oral bacterial adhesion to biomaterials....Pages 215-216
Analgesic effects of NOD1 and NOD2 agonists....Pages 217-219
Anaphylaxis-like shock induced by LPS plus antineutrophil monoclonal antibodies in mice....Pages 220-222
Concentrations of metal ions in murine nickel allergy and its cross-reactions: effects of lipopolysaccharide....Pages 223-224
Muramyldipeptide augments the actions of LPS via multiple fashions in mice....Pages 225-226
Isolation and identification of viable bacteria within acrylic resin denture bases....Pages 227-229
Bactericidal effect of photodynamic therapy....Pages 230-231
Induction of Tregs from PBMC by interacting with immunosuppressive molecule B7-H3 on oral mesenchymal stem cells....Pages 232-233
Front Matter....Pages 234-236
A method for determining the profiles of biomass volume and glucan within dental plaque....Pages 214-214
Profiling of dental plaque microflora on root caries lesions and the protein-degrading activity of these bacteria....Pages 237-239
Profiling of dental plaque biofilm on first molars with orthodontic bands and brackets....Pages 240-242
Hydrogen-sulfide production from various substrates by oral Veillonella and effects of lactate on the production....Pages 243-244
Detection of herpes simplex virus type 1 in human cadaver trigeminal ganglia....Pages 245-247
Transmitted laser beam power of the resin washed by experimental washing machine for dentures....Pages 248-249
The evaluation of the dental disinfection device with low concentration of H2O2 and laser diode....Pages 250-251
Rapid identification of HACEK group bacteria using 16S rRNA gene PCR-RFLP....Pages 252-254
Short-term effect of single NaF-mouthrinse on glucose-induced pH fall in dental plaque....Pages 255-256
Real-time PCR analysis of cariogenic bacteria in supragingival plaque biofilm microflora on caries lesions of children....Pages 257-258
Involvement of cough reflex impairment and silent aspiration of oral bacteria in postoperative pneumonia: a model of aspiration pneumonia....Pages 259-261
The production of secretory leukocyte protease inhibitor from gingival epithelial cells in response to Porphyromonas gingivalis lipopolysaccharides....Pages 262-264
Analysis of antigen incorporating and processing cells in sublingal immunotherapy....Pages 265-266
Acoustic mineral density measurement to evaluate clinical demineralized lesions....Pages 267-268
Front Matter....Pages 269-270
Experimental Ti–Ag alloys inhibit biofilm formation....Pages 271-272
Front Matter....Pages 273-274
Apatite formation from octacalcium phosphate with fluoride....Pages 275-276
Effect of topography of the octacalcium phosphate granule surfaces on its bone regenerative property....Pages 277-278
The influence of sericin solution on wettability and antifungal effect of resin surface....Pages 279-280
Adhesives and resin composites as functional units....Pages 282-282
Effects of bisphosphonates on bone marrow stromal cells....Pages 283-285
Tooth shape reconstruction from dental micro CT images....Pages 282-282
Formation of hydroxyapatite film on tooth using powder-jet-deposition....Pages 286-287
Electrodeposition of apatite onto titanium substrates under pulse current....Pages 288-290
Alginate/octacalcium phosphate composites enhance bone formation in critical-sized mouse calvaria defects....Pages 291-292
Strength of porcelain fused to Ti-20% Ag alloy made by CAD/CAM....Pages 294-296
Effect of various solutions to exudation of internal fluids from dentinal tubules....Pages 297-299
Evaluation of retentive force of ?-type Ti–6Mo–4Sn alloy wire to apply for the abutment tooth of removable partial denture....Pages 300-301
Medical application of magnesium and its alloys as degradable biomaterials....Pages 302-304
Front Matter....Pages 305-307
Difference between age generation of oral health examination in a rural town....Pages 308-310
Impact of oral health status on healthy life expectancy in community-dwelling population: The AGES Project cohort study....Pages 311-312
Wireless magnetic motion capture system for medical use....Pages 313-314
Evaluation of the optimal time of the dental treatment for the elderly....Pages 315-317
Educational effect on tooth preparation of visual feedback using computer graphics....Pages 318-320
Japanese men OSAHS patient’s anatomical features....Pages 322-322
Association between periodontal disease and risk for atherosclerosis in hypertensive patients....Pages 323-325
Front Matter....Pages 326-328
Leading a patient to a dental office: the evaluation of pain and stress during the dental treatment using an air-pad sensor system....Pages 329-331
Can symptom awareness of the elderly be a clue to find oral diseases and promote oral health behaviors?....Pages 332-334
The study of mandibular position applied to oral appliance for treatment of obstructive sleep apnea syndrome....Pages 335-336
Prediction of future number of remaining teeth of Japanese elderly, based on data from the national survey of dental diseases in Japan....Pages 337-340
National survey on the school-based fluoride mouth rinsing program in Japan: proposition regarding final assessment of Healthy Japan 21 in 2010, and in 2020....Pages 341-343
A new intra-oral pressure monitor for screening swallowing dysfunction....Pages 322-322
A numerical simulation method for dental occlusion with forces applied to the tooth in mandible....Pages 344-345
Front Matter....Pages 346-348
Osteopontin and CSF-1 in bone resorption....Pages 349-350
Role of amelogenin self-assembly in protein-mediated dental enamel formation....Pages 351-352
The human genetics of amelogenesis imperfecta....Pages 353-355
Building the genomic base-layer of the oral “omic” world....Pages 356-357
Cariogenic microflora and the immune response....Pages 358-359
Is RANKL shedding involved in immune cell-mediated osteoclastogenesis?....Pages 362-362
Possible IgG transportation mechanism mediated by neonatal Fc receptor expressed in gingival epithelial cells....Pages 363-368
Effects of extracellular adenosine on sRANKL production from activated T cells....Pages 369-374
Activation of the critical enamel protease kallikrein-4....Pages 375-381
Epitopes shared among pioneer oral flora and Streptococcus mutans GbpB....Pages 382-387
Inhibitory effect of porcine amelogenins on spontaneous mineralization....Pages 388-393
Back Matter....Pages 394-399
A stress-based mechanism to explain dental fluorosis....Pages 400-402
....Pages 403-405