Ebook: Functional Genomics

This volume provides an overview of the current state of plant genomics using a number of different approaches at a time when we celebrate the completion of the Arabidopsis genome sequence and begin the transition from structural to functional studies of this and other plant genomes. Topics covered include comparative genomics, computational approaches to gene identification and annotation and data management, high throughput methodologies for functional analysis at the levels of transcript, protein and metabolite, and methods for genome modification by both homologous and site-specific recombination. The book will provide a good introduction to some of the many aspects of genomics both for established plant biologists who wish to understand this rapidly developing area and for scientists early in their careers. It is also very suitable for a one-semester course in Plant Genomics at the upper-level undergraduate/graduate student level, where the individual chapters provide a framework that can be readily expanded by use of some of the many articles in the bibliographies.

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This volume provides an overview of the current state of plant genomics using a number of different approaches at a time when we celebrate the completion of the Arabidopsis genome sequence and begin the transition from structural to functional studies of this and other plant genomes. Topics covered include comparative genomics, computational approaches to gene identification and annotation and data management, high throughput methodologies for functional analysis at the levels of transcript, protein and metabolite, and methods for genome modification by both homologous and site-specific recombination. The book will provide a good introduction to some of the many aspects of genomics both for established plant biologists who wish to understand this rapidly developing area and for scientists early in their careers. It is also very suitable for a one-semester course in Plant Genomics at the upper-level undergraduate/graduate student level, where the individual chapters provide a framework that can be readily expanded by use of some of the many articles in the bibliographies.

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This volume provides an overview of the current state of plant genomics using a number of different approaches at a time when we celebrate the completion of the Arabidopsis genome sequence and begin the transition from structural to functional studies of this and other plant genomes. Topics covered include comparative genomics, computational approaches to gene identification and annotation and data management, high throughput methodologies for functional analysis at the levels of transcript, protein and metabolite, and methods for genome modification by both homologous and site-specific recombination. The book will provide a good introduction to some of the many aspects of genomics both for established plant biologists who wish to understand this rapidly developing area and for scientists early in their careers. It is also very suitable for a one-semester course in Plant Genomics at the upper-level undergraduate/graduate student level, where the individual chapters provide a framework that can be readily expanded by use of some of the many articles in the bibliographies.
Content:
Front Matter....Pages i-3
Through a genome, darkly: comparative analysis of plant chromosomal DNA....Pages 5-20
Plant genome evolution: lessons from comparative genomics at the DNA level....Pages 21-37
Computational gene finding in plants....Pages 39-48
Computational modeling of gene structure in Arabidopsis thaliana ....Pages 49-58
Surviving in a sea of data: a survey of plant genome data resources and issues in building data management systems....Pages 59-74
Comprehensive gene expression analysis by transcript profiling....Pages 75-97
DNA microarrays for functional plant genomics....Pages 99-118
Microarray data quality analysis: lessons from the AFGC project....Pages 119-131
Large-scale plant proteomics....Pages 133-141
Proteomics and a future generation of plant molecular biologists....Pages 143-154
Metabolomics — the link between genotypes and phenotypes....Pages 155-171
Gene replacement by homologous recombination in plants....Pages 173-182
Recombinase-directed plant transformation for the post-genomic era....Pages 183-200
Back Matter....Pages 201-205

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This volume provides an overview of the current state of plant genomics using a number of different approaches at a time when we celebrate the completion of the Arabidopsis genome sequence and begin the transition from structural to functional studies of this and other plant genomes. Topics covered include comparative genomics, computational approaches to gene identification and annotation and data management, high throughput methodologies for functional analysis at the levels of transcript, protein and metabolite, and methods for genome modification by both homologous and site-specific recombination. The book will provide a good introduction to some of the many aspects of genomics both for established plant biologists who wish to understand this rapidly developing area and for scientists early in their careers. It is also very suitable for a one-semester course in Plant Genomics at the upper-level undergraduate/graduate student level, where the individual chapters provide a framework that can be readily expanded by use of some of the many articles in the bibliographies.
Content:
Front Matter....Pages i-3
Through a genome, darkly: comparative analysis of plant chromosomal DNA....Pages 5-20
Plant genome evolution: lessons from comparative genomics at the DNA level....Pages 21-37
Computational gene finding in plants....Pages 39-48
Computational modeling of gene structure in Arabidopsis thaliana ....Pages 49-58
Surviving in a sea of data: a survey of plant genome data resources and issues in building data management systems....Pages 59-74
Comprehensive gene expression analysis by transcript profiling....Pages 75-97
DNA microarrays for functional plant genomics....Pages 99-118
Microarray data quality analysis: lessons from the AFGC project....Pages 119-131
Large-scale plant proteomics....Pages 133-141
Proteomics and a future generation of plant molecular biologists....Pages 143-154
Metabolomics — the link between genotypes and phenotypes....Pages 155-171
Gene replacement by homologous recombination in plants....Pages 173-182
Recombinase-directed plant transformation for the post-genomic era....Pages 183-200
Back Matter....Pages 201-205
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