Ebook: Engineering Biomaterials for Regenerative Medicine: Novel Technologies for Clinical Applications
- Tags: Biomaterials, Biomedical Engineering, Cell Biology, Polymer Sciences, Biochemical Engineering, Medical Microbiology
- Year: 2012
- Publisher: Springer-Verlag New York
- Edition: 1
- Language: English
- pdf
Regeneration of tissues and organs remains one of the great challenges of clinical medicine, and physicians are constantly seeking better methods for tissue repair and replacement. Tissue engineering and regenerative medicine have been investigated for virtually every organ system in the human body, and progress is made possible by advances in materials science, polymer chemistry, and molecular biology. This book reviews the current status of biomaterials for regenerative medicine, and highlights advances in both basic science and clinical practice. The latest methods for regulating the biological and chemical composition of biomaterials are described, together with techniques for modulating mechanical properties of engineered constructs. Contributors delineate methods for guiding the host response to implantable materials, and explain the use of biologically-inspired materials for optimal biological functionality and compatibility. The book culminates in a discussion of the clinical applications of regenerative medicine.
By integrating engineering and clinical medicine, Engineering Biomaterials for Regenerative Medicine examines how tissue engineering and regenerative medicine can be translated into successful therapies to bridge the gap between laboratory and clinic. The book will aid materials scientists and engineers in identifying research priorities to fulfill clinical needs, and will also enable physicians to understand novel biomaterials that are emerging in the clinic. This integrated approach also gives engineering students a sense of the excitement and relevance of materials science in the development of novel therapeutic strategies.
Regeneration of tissues and organs remains one of the great challenges of clinical medicine, and physicians are constantly seeking better methods for tissue repair and replacement. Tissue engineering and regenerative medicine have been investigated for virtually every organ system in the human body, and progress is made possible by advances in materials science, polymer chemistry, and molecular biology. This book reviews the current status of biomaterials for regenerative medicine, and highlights advances in both basic science and clinical practice. The latest methods for regulating the biological and chemical composition of biomaterials are described, together with techniques for modulating mechanical properties of engineered constructs. Contributors delineate methods for guiding the host response to implantable materials, and explain the use of biologically-inspired materials for optimal biological functionality and compatibility. The book culminates in a discussion of the clinical applications of regenerative medicine.
By integrating engineering and clinical medicine, Engineering Biomaterials for Regenerative Medicine examines how tissue engineering and regenerative medicine can be translated into successful therapies to bridge the gap between laboratory and clinic. The book will aid materials scientists and engineers in identifying research priorities to fulfill clinical needs, and will also enable physicians to understand novel biomaterials that are emerging in the clinic. This integrated approach also gives engineering students a sense of the excitement and relevance of materials science in the development of novel therapeutic strategies.
Details strategies for addressing specific disease states with tissue engineering and regenerative medicine
Discusses the latest generation of regenerative biomaterial
Regeneration of tissues and organs remains one of the great challenges of clinical medicine, and physicians are constantly seeking better methods for tissue repair and replacement. Tissue engineering and regenerative medicine have been investigated for virtually every organ system in the human body, and progress is made possible by advances in materials science, polymer chemistry, and molecular biology. This book reviews the current status of biomaterials for regenerative medicine, and highlights advances in both basic science and clinical practice. The latest methods for regulating the biological and chemical composition of biomaterials are described, together with techniques for modulating mechanical properties of engineered constructs. Contributors delineate methods for guiding the host response to implantable materials, and explain the use of biologically-inspired materials for optimal biological functionality and compatibility. The book culminates in a discussion of the clinical applications of regenerative medicine.
By integrating engineering and clinical medicine, Engineering Biomaterials for Regenerative Medicine examines how tissue engineering and regenerative medicine can be translated into successful therapies to bridge the gap between laboratory and clinic. The book will aid materials scientists and engineers in identifying research priorities to fulfill clinical needs, and will also enable physicians to understand novel biomaterials that are emerging in the clinic. This integrated approach also gives engineering students a sense of the excitement and relevance of materials science in the development of novel therapeutic strategies.
Details strategies for addressing specific disease states with tissue engineering and regenerative medicine
Discusses the latest generation of regenerative biomaterial
Content:
Front Matter....Pages i-x
Front Matter....Pages 1-1
Biomaterial Surfaces for the Isolation of Hematopoietic Stem and Progenitor Cells....Pages 3-17
Matrix Stiffness: A Regulator of Cellular Behavior and Tissue Formation....Pages 19-37
Front Matter....Pages 39-39
Oxygen Supply for Tissue Engineering....Pages 41-86
Front Matter....Pages 87-87
Adhesion Behavior of Soft Materials....Pages 89-125
PLA–PEO–PLA Hydrogels and Their Mechanical Properties....Pages 127-140
Front Matter....Pages 141-141
Host Response to Biomaterials....Pages 143-159
Modulation of the Wound Healing Response Through Oxidation Active Materials....Pages 161-192
Front Matter....Pages 193-193
Gecko-Inspired Tape-Based Adhesives....Pages 195-223
Heparin-Functionalized Materials in Tissue Engineering Applications....Pages 225-250
Front Matter....Pages 251-251
Tissue Engineering Strategies for Vocal Fold Repair and Regeneration....Pages 253-284
Nonviral Gene Delivery for Applications in Regenerative Medicine....Pages 285-319
Chitosan-Based Delivery System for Tissue Regeneration and Chemotherapy....Pages 321-343
Conclusion: Translating Tissue Engineering into Successful Therapies....Pages 345-346
Back Matter....Pages 347-352
Regeneration of tissues and organs remains one of the great challenges of clinical medicine, and physicians are constantly seeking better methods for tissue repair and replacement. Tissue engineering and regenerative medicine have been investigated for virtually every organ system in the human body, and progress is made possible by advances in materials science, polymer chemistry, and molecular biology. This book reviews the current status of biomaterials for regenerative medicine, and highlights advances in both basic science and clinical practice. The latest methods for regulating the biological and chemical composition of biomaterials are described, together with techniques for modulating mechanical properties of engineered constructs. Contributors delineate methods for guiding the host response to implantable materials, and explain the use of biologically-inspired materials for optimal biological functionality and compatibility. The book culminates in a discussion of the clinical applications of regenerative medicine.
By integrating engineering and clinical medicine, Engineering Biomaterials for Regenerative Medicine examines how tissue engineering and regenerative medicine can be translated into successful therapies to bridge the gap between laboratory and clinic. The book will aid materials scientists and engineers in identifying research priorities to fulfill clinical needs, and will also enable physicians to understand novel biomaterials that are emerging in the clinic. This integrated approach also gives engineering students a sense of the excitement and relevance of materials science in the development of novel therapeutic strategies.
Details strategies for addressing specific disease states with tissue engineering and regenerative medicine
Discusses the latest generation of regenerative biomaterial
Content:
Front Matter....Pages i-x
Front Matter....Pages 1-1
Biomaterial Surfaces for the Isolation of Hematopoietic Stem and Progenitor Cells....Pages 3-17
Matrix Stiffness: A Regulator of Cellular Behavior and Tissue Formation....Pages 19-37
Front Matter....Pages 39-39
Oxygen Supply for Tissue Engineering....Pages 41-86
Front Matter....Pages 87-87
Adhesion Behavior of Soft Materials....Pages 89-125
PLA–PEO–PLA Hydrogels and Their Mechanical Properties....Pages 127-140
Front Matter....Pages 141-141
Host Response to Biomaterials....Pages 143-159
Modulation of the Wound Healing Response Through Oxidation Active Materials....Pages 161-192
Front Matter....Pages 193-193
Gecko-Inspired Tape-Based Adhesives....Pages 195-223
Heparin-Functionalized Materials in Tissue Engineering Applications....Pages 225-250
Front Matter....Pages 251-251
Tissue Engineering Strategies for Vocal Fold Repair and Regeneration....Pages 253-284
Nonviral Gene Delivery for Applications in Regenerative Medicine....Pages 285-319
Chitosan-Based Delivery System for Tissue Regeneration and Chemotherapy....Pages 321-343
Conclusion: Translating Tissue Engineering into Successful Therapies....Pages 345-346
Back Matter....Pages 347-352
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