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Chemically and biologically functionalized piezoelectric sensors are attractive alternatives to surface-sensitive transducers due to their surpassing versatility. The fourth volume of the Springer Series on Chemical Sensors and Biosensors includes a comprehensive theoretical treatment and current state-of-the art applications of the quartz crystal microbalance (QCM). Interface circuits and the study of viscoelasticity and micromechanics as well as surface roughness with the QCM are discussed. The broad field of analytical applications of piezoelectric sensors is covered, which ranges from nucleic acid detection, immunosensors, protein-membrane interactions and monitoring cells by imprinted polymers to the viscoelastic response of living mammalian cells on QCM-resonators. Sophisticated derivatives of the classical QCM, such as rupture event scanning, the use of extraordinary high frequency crystals, and electrochemical QCM, clearly reveal the advantages of combining multiple techniques to realize new detection schemes on the basis of piezoelectric resonators.




Chemically and biologically functionalized piezoelectric sensors are attractive alternatives to surface-sensitive transducers due to their surpassing versatility. This fourth volume in the Springer Series on Chemical Sensors and Biosensors includes a comprehensive theoretical treatment and current state-of-the art applications of the quartz crystal microbalance (QCM). It discusses interface circuits and the study of viscoelasticity and micromechanics as well as surface roughness with the QCM. Coverage also details the broad field of analytical applications of piezoelectric sensors, which ranges from nucleic acid detection, immunosensors, protein-membrane interactions and monitoring cells by imprinted polymers to the viscoelastic response of living mammalian cells on QCM-resonators. Sophisticated derivatives of the classical QCM, such as rupture event scanning, the use of extraordinary high frequency crystals, and electrochemical QCM, clearly reveal the advantages of combining multiple techniques to realize new detection schemes on the basis of piezoelectric resonators.




Chemically and biologically functionalized piezoelectric sensors are attractive alternatives to surface-sensitive transducers due to their surpassing versatility. This fourth volume in the Springer Series on Chemical Sensors and Biosensors includes a comprehensive theoretical treatment and current state-of-the art applications of the quartz crystal microbalance (QCM). It discusses interface circuits and the study of viscoelasticity and micromechanics as well as surface roughness with the QCM. Coverage also details the broad field of analytical applications of piezoelectric sensors, which ranges from nucleic acid detection, immunosensors, protein-membrane interactions and monitoring cells by imprinted polymers to the viscoelastic response of living mammalian cells on QCM-resonators. Sophisticated derivatives of the classical QCM, such as rupture event scanning, the use of extraordinary high frequency crystals, and electrochemical QCM, clearly reveal the advantages of combining multiple techniques to realize new detection schemes on the basis of piezoelectric resonators.


Content:
Front Matter....Pages I-XII
Front Matter....Pages 1-1
Interface Circuits for QCM Sensors....Pages 3-47
Studies of Viscoelasticity with the QCM....Pages 49-109
Probing the Solid/Liquid Interface with the Quartz Crystal Microbalance....Pages 111-149
Studies of Contact Mechanics with the QCM....Pages 151-170
Front Matter....Pages 171-171
Imprinted Polymers in Chemical Recognition for Mass-Sensitive Devices....Pages 173-210
Analytical Applications of QCM-based Nucleic Acid Biosensors....Pages 211-235
Piezoelectric Immunosensors....Pages 237-280
Specific Adsorption of Annexin A1 on Solid Supported Membranes: A Model Study....Pages 281-302
The Quartz Crystal Microbalance in Cell Biology: Basics and Applications....Pages 303-338
Front Matter....Pages 339-339
Enzyme Reactions on a 27 MHz Quartz Crystal Microbalance....Pages 341-369
The Quartz Crystal Microbalance and the Electrochemical QCM: Applications to Studies of Thin Polymer Films, Electron Transfer Systems, Biological Macromolecules, Biosensors, and Cells....Pages 371-424
The QCM-D Technique for Probing Biomacromolecular Recognition Reactions....Pages 425-447
Resonant Acoustic Profiling (RAP™) and Rupture Event Scanning (REVS™)....Pages 449-479
Back Matter....Pages 481-483


Chemically and biologically functionalized piezoelectric sensors are attractive alternatives to surface-sensitive transducers due to their surpassing versatility. This fourth volume in the Springer Series on Chemical Sensors and Biosensors includes a comprehensive theoretical treatment and current state-of-the art applications of the quartz crystal microbalance (QCM). It discusses interface circuits and the study of viscoelasticity and micromechanics as well as surface roughness with the QCM. Coverage also details the broad field of analytical applications of piezoelectric sensors, which ranges from nucleic acid detection, immunosensors, protein-membrane interactions and monitoring cells by imprinted polymers to the viscoelastic response of living mammalian cells on QCM-resonators. Sophisticated derivatives of the classical QCM, such as rupture event scanning, the use of extraordinary high frequency crystals, and electrochemical QCM, clearly reveal the advantages of combining multiple techniques to realize new detection schemes on the basis of piezoelectric resonators.


Content:
Front Matter....Pages I-XII
Front Matter....Pages 1-1
Interface Circuits for QCM Sensors....Pages 3-47
Studies of Viscoelasticity with the QCM....Pages 49-109
Probing the Solid/Liquid Interface with the Quartz Crystal Microbalance....Pages 111-149
Studies of Contact Mechanics with the QCM....Pages 151-170
Front Matter....Pages 171-171
Imprinted Polymers in Chemical Recognition for Mass-Sensitive Devices....Pages 173-210
Analytical Applications of QCM-based Nucleic Acid Biosensors....Pages 211-235
Piezoelectric Immunosensors....Pages 237-280
Specific Adsorption of Annexin A1 on Solid Supported Membranes: A Model Study....Pages 281-302
The Quartz Crystal Microbalance in Cell Biology: Basics and Applications....Pages 303-338
Front Matter....Pages 339-339
Enzyme Reactions on a 27 MHz Quartz Crystal Microbalance....Pages 341-369
The Quartz Crystal Microbalance and the Electrochemical QCM: Applications to Studies of Thin Polymer Films, Electron Transfer Systems, Biological Macromolecules, Biosensors, and Cells....Pages 371-424
The QCM-D Technique for Probing Biomacromolecular Recognition Reactions....Pages 425-447
Resonant Acoustic Profiling (RAP™) and Rupture Event Scanning (REVS™)....Pages 449-479
Back Matter....Pages 481-483
....
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