Ebook: Computational Neurogenetic Modeling

Computational Neurogenetic ModelingIntegrating Bioinformatics and Neuroscience Data, Information and Knowledge via Computational Intelligence

Lubica Benuskova and Nikola Kasabov

With the presence of a great amount of both brain and gene data related to brain functions and diseases, it is required that sophisticated computational neurogenetic models be created to facilitate new discoveries that will help researchers in understanding the brain in its complex interaction between genetic and neuronal processes. Initial steps in this direction are underway, using the methods of computational intelligence to integrate knowledge, data and information from genetics, bioinfomatics and neuroscience.

Computational Neurogenetic Modeling offers the knowledge base for creating such models covering the areas of neuroscience, genetics, bioinformatics and computational intelligence. This multidisciplinary background is then integrated into a generic computational neurogenetic modeling methodology. computational neurogenetic models offer vital applications for learning and memory, brain aging and Alzheimer’s disease, Parkinson’s disease, mental retardation, schizophrenia and epilepsy.

Key Topics Include:

• Brain Information Processing
• Methods of Computational Intelligence, Including:

• Artificial Neural Networks
• Evolutionary Computation
• Evolving Connectionist Systems

• Gene Information Processing
• Methodologies for Building Computational Neurogenetic Models
• Applications of CNGM for modeling brain functions and diseases

Computational Neurogenetic Modeling is essential reading for postgraduate students and researchers in the areas of information sciences, artificial intelligence, neurosciences, bioinformatics and cognitive sciences. This volume is structured so that every chapter can be used as a reading material for research oriented courses at a postgraduate level.

About the Authors:

Lubica Benuskova is currently Senior Research Fellow at the Knowledge Engineering & Discovery Research Institute (KEDRI, www.kedri.info), Auckland University of Technology (AUT) in Auckland, New Zealand. She is also Associate Professor of Applied Informatics at the Faculty of Mathematics, Physics and Informatics at Comenius (Komensky) University in Bratislava, Slovakia. Her research interests are in the areas of computational neuroscience, cognitive science, neuroinformatics, computer and information sciences.

Nikola Kasabov is the Founding Director and Chief Scientist of KEDRI, and a Professor and Chair of Knowledge Engineering at the School of Computer and Information Sciences at AUT. He is a leading expert in computational intelligence and knowledge engineering and has published more than 400 papers, books and patents in the areas of neural and hybrid intelligent systems, bioinformatics and neuroinformatics, speech-, image and multimodal information processing. He is a Fellow of the Royal Society of New Zealand, Senior Member of IEEE, Vice President of the International Neural Network Society and a Past President of the Asia-Pacific Neural Network Assembly.

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Computational Neurogenetic Modeling                                                                   Integrating Bioinformatics and Neuroscience Data, Information and Knowledge via Computational Intelligence

Lubica Benuskova and Nikola Kasabov

With the presence of a great amount of both brain and gene data related to brain functions and diseases, it is required that sophisticated computational neurogenetic models be created to facilitate new discoveries that will help researchers in understanding the brain in its complex interaction between genetic and neuronal processes. Initial steps in this direction are underway, using the methods of computational intelligence to integrate knowledge, data and information from genetics, bioinfomatics and neuroscience.

Computational Neurogenetic Modeling offers the knowledge base for creating such models covering the areas of neuroscience, genetics, bioinformatics and computational intelligence. This multidisciplinary background is then integrated into a generic computational neurogenetic modeling methodology. computational neurogenetic models offer vital applications for learning and memory, brain aging and Alzheimer’s disease, Parkinson’s disease, mental retardation, schizophrenia and epilepsy.  

Key Topics Include:

• Brain Information Processing
• Methods of Computational Intelligence, Including:

• Artificial Neural Networks
• Evolutionary Computation
• Evolving Connectionist Systems

• Gene Information Processing
• Methodologies for Building Computational Neurogenetic Models
• Applications of CNGM for modeling brain functions and diseases

Computational Neurogenetic Modeling is essential reading for postgraduate students and researchers in the areas of information sciences, artificial intelligence, neurosciences, bioinformatics and cognitive sciences. This volume is structured so that every chapter can be used as a reading material for research oriented courses at a postgraduate level.

About the Authors:

Lubica Benuskova is currently Senior Research Fellow at the Knowledge Engineering & Discovery Research Institute (KEDRI, www.kedri.info), Auckland University of Technology (AUT) in Auckland, New Zealand. She is also Associate Professor of Applied Informatics at the Faculty of Mathematics, Physics and Informatics at Comenius (Komensky) University in Bratislava, Slovakia. Her research interests are in the areas of computational neuroscience, cognitive science, neuroinformatics, computer and information sciences.

Nikola Kasabov is the Founding Director and Chief Scientist of KEDRI, and a Professor and Chair of Knowledge Engineering at the School of Computer and Information Sciences at AUT. He is a leading expert in computational intelligence and knowledge engineering and has published more than 400 papers, books and patents in the areas of neural and hybrid intelligent systems, bioinformatics and neuroinformatics, speech-, image and multimodal information processing. He is a Fellow of the Royal Society of New Zealand, Senior Member of IEEE, Vice President of the International Neural Network Society and a Past President of the Asia-Pacific Neural Network Assembly.

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Computational Neurogenetic Modeling                                                                   Integrating Bioinformatics and Neuroscience Data, Information and Knowledge via Computational Intelligence

Lubica Benuskova and Nikola Kasabov

With the presence of a great amount of both brain and gene data related to brain functions and diseases, it is required that sophisticated computational neurogenetic models be created to facilitate new discoveries that will help researchers in understanding the brain in its complex interaction between genetic and neuronal processes. Initial steps in this direction are underway, using the methods of computational intelligence to integrate knowledge, data and information from genetics, bioinfomatics and neuroscience.

Computational Neurogenetic Modeling offers the knowledge base for creating such models covering the areas of neuroscience, genetics, bioinformatics and computational intelligence. This multidisciplinary background is then integrated into a generic computational neurogenetic modeling methodology. computational neurogenetic models offer vital applications for learning and memory, brain aging and Alzheimer’s disease, Parkinson’s disease, mental retardation, schizophrenia and epilepsy.  

Key Topics Include:

• Brain Information Processing
• Methods of Computational Intelligence, Including:

• Artificial Neural Networks
• Evolutionary Computation
• Evolving Connectionist Systems

• Gene Information Processing
• Methodologies for Building Computational Neurogenetic Models
• Applications of CNGM for modeling brain functions and diseases

Computational Neurogenetic Modeling is essential reading for postgraduate students and researchers in the areas of information sciences, artificial intelligence, neurosciences, bioinformatics and cognitive sciences. This volume is structured so that every chapter can be used as a reading material for research oriented courses at a postgraduate level.

About the Authors:

Lubica Benuskova is currently Senior Research Fellow at the Knowledge Engineering & Discovery Research Institute (KEDRI, www.kedri.info), Auckland University of Technology (AUT) in Auckland, New Zealand. She is also Associate Professor of Applied Informatics at the Faculty of Mathematics, Physics and Informatics at Comenius (Komensky) University in Bratislava, Slovakia. Her research interests are in the areas of computational neuroscience, cognitive science, neuroinformatics, computer and information sciences.

Nikola Kasabov is the Founding Director and Chief Scientist of KEDRI, and a Professor and Chair of Knowledge Engineering at the School of Computer and Information Sciences at AUT. He is a leading expert in computational intelligence and knowledge engineering and has published more than 400 papers, books and patents in the areas of neural and hybrid intelligent systems, bioinformatics and neuroinformatics, speech-, image and multimodal information processing. He is a Fellow of the Royal Society of New Zealand, Senior Member of IEEE, Vice President of the International Neural Network Society and a Past President of the Asia-Pacific Neural Network Assembly.

Content:
Front Matter....Pages I-XII
Computational Neurogenetic Modeling (CNGM): A Brief Introduction....Pages 1-16
Organization and Functions of the Brain....Pages 17-51
Neuro-Information Processing in the Brain....Pages 53-80
Artificial Neural Networks (ANN)....Pages 81-106
Evolving Connectionist Systems (ECOS)....Pages 107-126
Evolutionary Computation for Model and Feature Optimization....Pages 127-136
Gene/Protein Interactions — Modeling Gene Regulatory Networks (GRN)....Pages 137-153
CNGM as Integration of GPRN, ANN and Evolving Processes....Pages 155-176
Application of CNGM to Learning and Memory....Pages 177-203
Applications of CNGM and Future Development....Pages 205-236
Back Matter....Pages 237-290

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Computational Neurogenetic Modeling                                                                   Integrating Bioinformatics and Neuroscience Data, Information and Knowledge via Computational Intelligence

Lubica Benuskova and Nikola Kasabov

With the presence of a great amount of both brain and gene data related to brain functions and diseases, it is required that sophisticated computational neurogenetic models be created to facilitate new discoveries that will help researchers in understanding the brain in its complex interaction between genetic and neuronal processes. Initial steps in this direction are underway, using the methods of computational intelligence to integrate knowledge, data and information from genetics, bioinfomatics and neuroscience.

Computational Neurogenetic Modeling offers the knowledge base for creating such models covering the areas of neuroscience, genetics, bioinformatics and computational intelligence. This multidisciplinary background is then integrated into a generic computational neurogenetic modeling methodology. computational neurogenetic models offer vital applications for learning and memory, brain aging and Alzheimer’s disease, Parkinson’s disease, mental retardation, schizophrenia and epilepsy.  

Key Topics Include:

• Brain Information Processing
• Methods of Computational Intelligence, Including:

• Artificial Neural Networks
• Evolutionary Computation
• Evolving Connectionist Systems

• Gene Information Processing
• Methodologies for Building Computational Neurogenetic Models
• Applications of CNGM for modeling brain functions and diseases

Computational Neurogenetic Modeling is essential reading for postgraduate students and researchers in the areas of information sciences, artificial intelligence, neurosciences, bioinformatics and cognitive sciences. This volume is structured so that every chapter can be used as a reading material for research oriented courses at a postgraduate level.

About the Authors:

Lubica Benuskova is currently Senior Research Fellow at the Knowledge Engineering & Discovery Research Institute (KEDRI, www.kedri.info), Auckland University of Technology (AUT) in Auckland, New Zealand. She is also Associate Professor of Applied Informatics at the Faculty of Mathematics, Physics and Informatics at Comenius (Komensky) University in Bratislava, Slovakia. Her research interests are in the areas of computational neuroscience, cognitive science, neuroinformatics, computer and information sciences.

Nikola Kasabov is the Founding Director and Chief Scientist of KEDRI, and a Professor and Chair of Knowledge Engineering at the School of Computer and Information Sciences at AUT. He is a leading expert in computational intelligence and knowledge engineering and has published more than 400 papers, books and patents in the areas of neural and hybrid intelligent systems, bioinformatics and neuroinformatics, speech-, image and multimodal information processing. He is a Fellow of the Royal Society of New Zealand, Senior Member of IEEE, Vice President of the International Neural Network Society and a Past President of the Asia-Pacific Neural Network Assembly.

Content:
Front Matter....Pages I-XII
Computational Neurogenetic Modeling (CNGM): A Brief Introduction....Pages 1-16
Organization and Functions of the Brain....Pages 17-51
Neuro-Information Processing in the Brain....Pages 53-80
Artificial Neural Networks (ANN)....Pages 81-106
Evolving Connectionist Systems (ECOS)....Pages 107-126
Evolutionary Computation for Model and Feature Optimization....Pages 127-136
Gene/Protein Interactions — Modeling Gene Regulatory Networks (GRN)....Pages 137-153
CNGM as Integration of GPRN, ANN and Evolving Processes....Pages 155-176
Application of CNGM to Learning and Memory....Pages 177-203
Applications of CNGM and Future Development....Pages 205-236
Back Matter....Pages 237-290
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