Ebook: Californium-252 Isotope for 21st Century Radiotherapy

Californium-252 is a neutron emitter with a high specific activity, making it useful in a variety of applications, the most spectacular of which is in brachytherapy for cancer patients. Radiation oncology has exhausted nearly every option for treating radioresistant tumors by photon brachytherapy, and therefore new types of radiation need to be studied to improve the curability of cancer.
Audience: Californium brachytherapy is used in only a few radiation therapy centers in the world, so the book will be highly instructive for radiation oncologists, medical physicists and radiobiologists. The nuclear techniques used in clinical applications may also interest nuclear physicists and engineers.

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Content:
Front Matter....Pages i-xxi
Yosh Maruyama (1930–1995)....Pages 1-3
Front Matter....Pages 5-5
Californium-252 Production and Neutron Source Fabrication....Pages 7-24
Physics and Dosimetry of Clinical 252Cf Sources....Pages 25-53
Front Matter....Pages 55-55
The Relationship of 252Cf and 226Ra Radiation Doses to the Reoxygenation and Regression of Cervix Uteri Tumors....Pages 57-75
The Relationship of 252Cf and226Ra Radiation Doses and the Reoxygenation to Regression of the Cervix Uteri Tumor....Pages 77-82
Californium-252 and Hypoxyradiotherapy in Treatment of Advanced Carcinoma of the Cervix Uteri....Pages 83-97
Results of Mixed Radiation Therapy of Endometrial Cancer Using Neutron Gamma-Therapy....Pages 99-103
Preoperative Intracavitary Neutron Therapy Carcinoma of Endometrial and Cervix....Pages 105-113
The Results of Treatment of Patients with Endometrial Cancer and Carcinoma Cervix using Californium-252 HDR....Pages 115-130
Clinical Experience of Neutron Brachytherapy for Patients with Cervix Carcinoma....Pages 131-134
Front Matter....Pages 135-135
Radiation Injuries of Oral Cavity and Oropharynx after Interstitial Neutron Brachytherapy and Gamma-Therapy....Pages 137-144
Brachytherapy with Californium-252 for Head and Neck Tumors....Pages 145-158
Immunoendocrine Homeostasis State in Patients with Cancer of the Buccal Mucosa after Interstitial Therapy with Californium-252....Pages 159-176
Front Matter....Pages 177-177
Intracavitary Neutron Therapy for Malignant Rectal Tumors using High Activity Cf-252 Sources....Pages 179-198
Preoperative Radiotherapy in the Treatment of Rectal Carcinoma....Pages 199-201
Californium-252 in the Treatment of Soft Tissue Sarcoma....Pages 203-207
Front Matter....Pages 209-209
Treatment Planning for Interstitial and Intracavitary Cf-252 Neutron Brachytherapy....Pages 211-219
Dosimetry and Treatment Planning in High Dose Rate Cf-252 Brachytherapy....Pages 221-231
To the Problem on Selection of the Target in Brachytherapy with Cf-252....Pages 233-241
Factors Influencing the Efficiency of Cf-252 Brachytherapy: Clinical and Technological Aspects....Pages 243-256
Front Matter....Pages 209-209
Biological Effects of Gamma-Neutron Radiation Cf-252 or Fission Neutron from the Br-10 Reactor on Tumor and Normal Cells and Tissues....Pages 257-261
CF-252 Brachytherapy in Cervical Cancer: Monte Carlo Studies of the Effect of Tissue Heterogeneity....Pages 263-269
Front Matter....Pages 271-271
Automatic Afterloading Device for Neutron Brachytherapy (ANET-BA)....Pages 273-282
Small Accelerators - an Alternative Source of Neutrons for Brachytherapy....Pages 283-286
The IEC as a Complementary Neutron Source to Cf-252....Pages 287-297
Back Matter....Pages 299-300

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Content:
Front Matter....Pages i-xxi
Yosh Maruyama (1930–1995)....Pages 1-3
Front Matter....Pages 5-5
Californium-252 Production and Neutron Source Fabrication....Pages 7-24
Physics and Dosimetry of Clinical 252Cf Sources....Pages 25-53
Front Matter....Pages 55-55
The Relationship of 252Cf and 226Ra Radiation Doses to the Reoxygenation and Regression of Cervix Uteri Tumors....Pages 57-75
The Relationship of 252Cf and226Ra Radiation Doses and the Reoxygenation to Regression of the Cervix Uteri Tumor....Pages 77-82
Californium-252 and Hypoxyradiotherapy in Treatment of Advanced Carcinoma of the Cervix Uteri....Pages 83-97
Results of Mixed Radiation Therapy of Endometrial Cancer Using Neutron Gamma-Therapy....Pages 99-103
Preoperative Intracavitary Neutron Therapy Carcinoma of Endometrial and Cervix....Pages 105-113
The Results of Treatment of Patients with Endometrial Cancer and Carcinoma Cervix using Californium-252 HDR....Pages 115-130
Clinical Experience of Neutron Brachytherapy for Patients with Cervix Carcinoma....Pages 131-134
Front Matter....Pages 135-135
Radiation Injuries of Oral Cavity and Oropharynx after Interstitial Neutron Brachytherapy and Gamma-Therapy....Pages 137-144
Brachytherapy with Californium-252 for Head and Neck Tumors....Pages 145-158
Immunoendocrine Homeostasis State in Patients with Cancer of the Buccal Mucosa after Interstitial Therapy with Californium-252....Pages 159-176
Front Matter....Pages 177-177
Intracavitary Neutron Therapy for Malignant Rectal Tumors using High Activity Cf-252 Sources....Pages 179-198
Preoperative Radiotherapy in the Treatment of Rectal Carcinoma....Pages 199-201
Californium-252 in the Treatment of Soft Tissue Sarcoma....Pages 203-207
Front Matter....Pages 209-209
Treatment Planning for Interstitial and Intracavitary Cf-252 Neutron Brachytherapy....Pages 211-219
Dosimetry and Treatment Planning in High Dose Rate Cf-252 Brachytherapy....Pages 221-231
To the Problem on Selection of the Target in Brachytherapy with Cf-252....Pages 233-241
Factors Influencing the Efficiency of Cf-252 Brachytherapy: Clinical and Technological Aspects....Pages 243-256
Front Matter....Pages 209-209
Biological Effects of Gamma-Neutron Radiation Cf-252 or Fission Neutron from the Br-10 Reactor on Tumor and Normal Cells and Tissues....Pages 257-261
CF-252 Brachytherapy in Cervical Cancer: Monte Carlo Studies of the Effect of Tissue Heterogeneity....Pages 263-269
Front Matter....Pages 271-271
Automatic Afterloading Device for Neutron Brachytherapy (ANET-BA)....Pages 273-282
Small Accelerators - an Alternative Source of Neutrons for Brachytherapy....Pages 283-286
The IEC as a Complementary Neutron Source to Cf-252....Pages 287-297
Back Matter....Pages 299-300
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