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Drug interactions and adverse drug effects are responsible for the hospitalization and extended hospitalization of more than 100,000 Americans annually, not to mention a significant number of deaths. In Handbook of Drug Interactions: A Clinical and Forensic Guide, leading drug experts from pharmacology, toxicology, medicine, nutrition, and law have compiled a concise record of the known interactions of the most commonly prescribed drugs, as well as their interaction with nonprescription compounds. The agents covered include CNS drugs, cardiovascular drugs, antibiotics, and NSAIDs. The authors review the pharmacology, pharmacodynamics, pharmacokinetics, chemistry, metabolism, epidemiological occurrences, adverse reactions, and significant interactions for each class of drugs. Where necessary, they also consider forensic factors and implications for criminal law, malpractice, and tort litigation. Environmental and social pharmacological issues are also addressed in chapters on food and alcohol drug interactions, nicotine and tobacco, and anabolic doping agents. Individual chapters are devoted to drug interaction litigation and the role of psychotropic medications in crime. A detailed index provides rapid access to the book's extensive information on potential interactions.
Comprehensive and thorough, Handbook of Drug Interactions: A Clinical and Forensic Guide provides physicians with all the information needed to avoid prescribing drugs with undesirable interactions, and those active in clinical chemistry and laboratory medicine with all the data necessary to interpret possible interactions between drugs found simultaneously in patient samples.




Drug interactions and adverse drug effects are responsible for the hospitalization and extended hospitalization of more than 100,000 Americans annually, not to mention a significant number of deaths. In Handbook of Drug Interactions: A Clinical and Forensic Guide, leading drug experts from pharmacology, toxicology, medicine, nutrition, and law have compiled a concise record of the known interactions of the most commonly prescribed drugs, as well as their interaction with nonprescription compounds. The agents covered include CNS drugs, cardiovascular drugs, antibiotics, and NSAIDs. The authors review the pharmacology, pharmacodynamics, pharmacokinetics, chemistry, metabolism, epidemiological occurrences, adverse reactions, and significant interactions for each class of drugs. Where necessary, they also consider forensic factors and implications for criminal law, malpractice, and tort litigation. Environmental and social pharmacological issues are also addressed in chapters on food and alcohol drug interactions, nicotine and tobacco, and anabolic doping agents. Individual chapters are devoted to drug interaction litigation and the role of psychotropic medications in crime. A detailed index provides rapid access to the book's extensive information on potential interactions.
Comprehensive and thorough, Handbook of Drug Interactions: A Clinical and Forensic Guide provides physicians with all the information needed to avoid prescribing drugs with undesirable interactions, and those active in clinical chemistry and laboratory medicine with all the data necessary to interpret possible interactions between drugs found simultaneously in patient samples.


Drug interactions and adverse drug effects are responsible for the hospitalization and extended hospitalization of more than 100,000 Americans annually, not to mention a significant number of deaths. In Handbook of Drug Interactions: A Clinical and Forensic Guide, leading drug experts from pharmacology, toxicology, medicine, nutrition, and law have compiled a concise record of the known interactions of the most commonly prescribed drugs, as well as their interaction with nonprescription compounds. The agents covered include CNS drugs, cardiovascular drugs, antibiotics, and NSAIDs. The authors review the pharmacology, pharmacodynamics, pharmacokinetics, chemistry, metabolism, epidemiological occurrences, adverse reactions, and significant interactions for each class of drugs. Where necessary, they also consider forensic factors and implications for criminal law, malpractice, and tort litigation. Environmental and social pharmacological issues are also addressed in chapters on food and alcohol drug interactions, nicotine and tobacco, and anabolic doping agents. Individual chapters are devoted to drug interaction litigation and the role of psychotropic medications in crime. A detailed index provides rapid access to the book's extensive information on potential interactions.
Comprehensive and thorough, Handbook of Drug Interactions: A Clinical and Forensic Guide provides physicians with all the information needed to avoid prescribing drugs with undesirable interactions, and those active in clinical chemistry and laboratory medicine with all the data necessary to interpret possible interactions between drugs found simultaneously in patient samples.
Content:
Front Matter....Pages i-x
Front Matter....Pages 1-1
Drug Interactions with Benzodiazepines....Pages 3-88
Antiepileptic Drugs....Pages 89-122
Opioids and Opiates....Pages 123-148
Monoamine Oxidase Inhibitors and Tricyclic Antidepressants....Pages 149-173
Selective Serotonin Reuptake Inhibitors....Pages 175-185
Antipsychotic Drugs and Interactions....Pages 187-215
Front Matter....Pages 217-217
Cardiovascular Drugs....Pages 219-292
Front Matter....Pages 293-293
Antimicrobial Drugs....Pages 295-318
Drug Interactions with Medications Used for HIV/AIDS....Pages 319-334
Front Matter....Pages 335-335
Nonsteroidal Antiinflammatory Drugs....Pages 337-376
Front Matter....Pages 377-377
Food and Drug Interactions....Pages 379-393
Alcohol and Drug Interactions....Pages 395-462
Nicotine and Tobacco....Pages 463-492
Anabolic Doping Agents....Pages 493-596
Front Matter....Pages 597-597
Drug Interaction Litigation....Pages 599-629
Psychotropic Medications and Crime....Pages 631-645
Back Matter....Pages 647-663


Drug interactions and adverse drug effects are responsible for the hospitalization and extended hospitalization of more than 100,000 Americans annually, not to mention a significant number of deaths. In Handbook of Drug Interactions: A Clinical and Forensic Guide, leading drug experts from pharmacology, toxicology, medicine, nutrition, and law have compiled a concise record of the known interactions of the most commonly prescribed drugs, as well as their interaction with nonprescription compounds. The agents covered include CNS drugs, cardiovascular drugs, antibiotics, and NSAIDs. The authors review the pharmacology, pharmacodynamics, pharmacokinetics, chemistry, metabolism, epidemiological occurrences, adverse reactions, and significant interactions for each class of drugs. Where necessary, they also consider forensic factors and implications for criminal law, malpractice, and tort litigation. Environmental and social pharmacological issues are also addressed in chapters on food and alcohol drug interactions, nicotine and tobacco, and anabolic doping agents. Individual chapters are devoted to drug interaction litigation and the role of psychotropic medications in crime. A detailed index provides rapid access to the book's extensive information on potential interactions.
Comprehensive and thorough, Handbook of Drug Interactions: A Clinical and Forensic Guide provides physicians with all the information needed to avoid prescribing drugs with undesirable interactions, and those active in clinical chemistry and laboratory medicine with all the data necessary to interpret possible interactions between drugs found simultaneously in patient samples.
Content:
Front Matter....Pages i-x
Front Matter....Pages 1-1
Drug Interactions with Benzodiazepines....Pages 3-88
Antiepileptic Drugs....Pages 89-122
Opioids and Opiates....Pages 123-148
Monoamine Oxidase Inhibitors and Tricyclic Antidepressants....Pages 149-173
Selective Serotonin Reuptake Inhibitors....Pages 175-185
Antipsychotic Drugs and Interactions....Pages 187-215
Front Matter....Pages 217-217
Cardiovascular Drugs....Pages 219-292
Front Matter....Pages 293-293
Antimicrobial Drugs....Pages 295-318
Drug Interactions with Medications Used for HIV/AIDS....Pages 319-334
Front Matter....Pages 335-335
Nonsteroidal Antiinflammatory Drugs....Pages 337-376
Front Matter....Pages 377-377
Food and Drug Interactions....Pages 379-393
Alcohol and Drug Interactions....Pages 395-462
Nicotine and Tobacco....Pages 463-492
Anabolic Doping Agents....Pages 493-596
Front Matter....Pages 597-597
Drug Interaction Litigation....Pages 599-629
Psychotropic Medications and Crime....Pages 631-645
Back Matter....Pages 647-663
....
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