Ebook: Signal Transduction by G Protein-Coupled Receptors: Bioenergetics and G Protein Activation: Proton Transfer and GTP Synthesis to Explain the Experimental Findings
Author: Paul H. J. Nederkoorn Ph.D. Henk Timmerman Ph.D. Gabriëlle M. Donné-Op den Kelder Ph.D. (auth.)
- Tags: Medical Microbiology
- Series: Molecular Biology Intelligence Unit
- Year: 1997
- Publisher: Springer US
- Edition: 1
- Language: English
- pdf
Content:
Front Matter....Pages i-xiv
Front Matter....Pages 1-1
Bioenergetics....Pages 3-16
Primary and Secondary Proton Pumps....Pages 17-26
ATP Hydrolysis and Synthesis Mechanisms....Pages 27-39
Front Matter....Pages 41-41
G Protein-Coupled Receptors and G Proteins....Pages 43-62
The (Extended) Ternary Complex Model ([E]TCM) for G Protein Activation....Pages 63-73
Nucleotide Exchange Reactions and G Protein Activation....Pages 75-92
A New Mechanism for G Protein Activation....Pages 93-111
Principles of a New Molecular Mechanism for Signal Transduction....Pages 113-141
Conclusions and Future Perspectives....Pages 143-148
Back Matter....Pages 149-151
Content:
Front Matter....Pages i-xiv
Front Matter....Pages 1-1
Bioenergetics....Pages 3-16
Primary and Secondary Proton Pumps....Pages 17-26
ATP Hydrolysis and Synthesis Mechanisms....Pages 27-39
Front Matter....Pages 41-41
G Protein-Coupled Receptors and G Proteins....Pages 43-62
The (Extended) Ternary Complex Model ([E]TCM) for G Protein Activation....Pages 63-73
Nucleotide Exchange Reactions and G Protein Activation....Pages 75-92
A New Mechanism for G Protein Activation....Pages 93-111
Principles of a New Molecular Mechanism for Signal Transduction....Pages 113-141
Conclusions and Future Perspectives....Pages 143-148
Back Matter....Pages 149-151
....
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