Ebook: Conformationally Directed Drug Design. Peptides and Nucleic Acids as Templates or Targets

Content: Virus-receptor interactions / Bernard N. Fields and Mark I. Greene --
Design of peptide superagonists and antagonists : conformational and dynamic considerations / Victor J. Hruby --
Localization and synthesis of protein antigenic sites : use of free synthetic peptides for the preparation of antibodies and T-cells of preselected specificities / M. Zouhair Atassi --
Studies on new microbial secondary metabolites with potential usefulness : antibiotics, enzyme inhibitors, and immunomodifiers / Hamao Umezawa --
Conformation of nucleic acids and their interactions with drugs / Andrew H.-J. Wang --
Substrate analog inhibitors of highly specific proteases / James Burton --
Structure-behavioral activity relationships of peptides derived from ACTH : some stereochemical considerations / J.W. Van Nispen and H.M. Greven --
Design of novel cyclic hexapeptide somatostatin analogs from a model of the bioactive conformation / Roger M. Freidinger and Daniel F. Veber --
Design of kinase inhibitors : conformational and mechanistic considerations / George L. Kenyon and Rebecca E. Reddick --
Design and discovery of aspartyl protease inhibitors : mechanistic and clinical implications / Daniel H. Rich, Francesco G. Salituro, Mark W. Holladay, and Paul G. Schmidt --
Design of peptide analogs : theoretical simulation of conformation, energetics, and dynamics / R.S. Struthers, A.T. Hagler, and J. Rivier.