Ebook: Biosimulation : simulation of living systems

"This practical guide to biosimulation provides the hands-on experience needed to devise, design and analyze simulations of biophysical processes for applications in biological and biomedical sciences. Through real-world case studies and worked examples, students will develop and apply basic operations through to advanced concepts, covering a wide range of biophysical topics including chemical kinetics and thermodynamics, transport phenomena, and cellular electrophysiology. Each chapter is built around case studies in a given application area, with simulations of real biological systems developed to analyze and interpret data. Open-ended project-based exercises are provided at the end of each chapter, and with all data and computer codes available online (www.cambridge.org/biosim) students can quickly and easily run, manipulate, explore and expand on the examples inside. This hands-on guide is ideal for use on senior undergraduate/graduate courses and also as a self-study guide for anyone who needs to develop computational models of biological systems"-- Read more... 1. Introduction to simulation of biological systems -- 2. Transport and reaction of solutes in biological systems -- 3. Physiologically based pharmacokinetic modeling -- 4. Cardiovascular systems simulation -- 5. Chemical reaction systems: thermodynamics and chemical equilibrium -- 6. Chemical reaction systems: kinetics -- 7. Chemical reaction systems: large-scale systems simulation -- 8. Cellular electrophysiology -- 9. Appendices: mathematical and computational techniques