Ebook: Introduction to Strategies for Organic Synthesis

This book will demonstrate how to synthesize target molecules (TMs) that
contain various functional groups (FGs), such as C≡C (alkyne), OH (alcohol
or carboxylic acid), and C=O (aldehyde, ketone, and many others). The process
of planning a synthesis, called a retrosynthesis, is one of the most critical tools
within the “toolbox” needed to solve synthesis problems. The method of retrosynthetic
analysis is introduced in this chapter and is used throughout the
book. This first chapter will also review the use of protective groups (PGs) in
organic synthesis. The second chapter provides additional useful tools needed
by the beginning synthesis student by reviewing common nucleophiles and
electrophiles, as well as some general reagents for oxidation and reduction
reactions.