Ebook: Comprehensive Organic Functional Group Transformations, Volume 2 (Synthesis: Carbon with One Heteroatom Attached by a Single Bond)

This Volume describes all methods for the synthesis of compounds containing acarbon atom singly bonded to a heteroatom substituent. The Volume is arranged in three parts dealing with sp3, sp2 and sp carbon linked to the heteroatoms. For each section careful attention has been given to various features such as substitution patterns, ring effects, strain effects, neighbouring functionality, stereochemistry, etc. which could mediate the synthesis pathway. Emphasis has also been given to the most convenient and practical preparation of the various functional groups. Critical assessment ofthe procedures allows the reader to select methods most appropriate for their needs. In this Volume the heteroatom may also be metallic and therefore reflect a highly polarised bonding arrangement with the carbon substituent. Compounds containing single bonds between carbon and heterofunctional groups constitute the largest class and most commonly transformed organic functional groups.