Ebook: Enzybiotics: Antibiotic Enzymes as Drugs and Therapeutics

Presents the latest research and applications for a new, promising approach to fighting infectious diseasesEnzybiotics is a promising way of fighting bacterial or fungal infectious diseases by using viruses or viral-derived lysins. Drawing from the fields of medicinal chemistry, microbiology, genetics, and biochemistry, this book presents the state of the science in enzybiotics research, fully exploring its emerging therapeutic applications.The book begins with four chapters that review the potential applications, possible advantages, and phylogeny of enzybiotics. Next, the book explores: A new approach to controlling infections using Gram-negative bacteriaBacteriophage holins and their membrane-disrupting activityAnti-staphylococcal lytic enzymesMembrane-targeted enzybioticsDesign of phage cocktails for therapy from a host-range point of viewNovel methods to identify new enzybioticsGenetically modified phages that deliver suicidal genes to target bacteriaThe authors, all active enzybiotics researchers, offer a variety of perspectives, the benefit of their own hands-on investigations, as well as a thorough review and analysis of the current literature.As more and more bacteria become resistant to antibiotics, the development of new disease-fighting agents has become essential. This book demonstrates the full potential of the emerging field of enzybiotics to control infectious diseases. Moreover, it will serve as a springboard for new research and the development of new therapeutics.