Ebook: CACO-2 Cells and their Uses
Author: Megan A. Schulz
- Tags: Epithelial cells., Monomolecular films., Intestinal absorption.
- Series: Cell Biology Research Progress
- Year: 2011
- Publisher: Nova Science Publishers
- City: Hauppauge, United States
- Edition: 1
- Language: English
- pdf
CACO-2 cell cultures are widely used in vitro models in several scientific fields such as nutrition, physiopathology, pharmacology, and toxicology. When cultured onto filters, these cells form a highly polarized epithelium that allows discrimination between apical and basolateral compartments. This new book presents topical research in the study of CACO-2 cells and their uses. Topics discussed include the application of CACO-2 cell models as a supportive in vitro tool during drug discovery and formulation; co-culture systems with CACO-2 cells to evaluate the bioactivity of plant extracts and the use of CACO-2 cells in intestinal transport, cell-matrix interactions and wound healing in intestinal villus cells.
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