Ebook: ENHANZE® Drug Delivery Technology: Advancing Subcutaneous Drug Delivery Using Recombinant Human Hyaluronidase PH20
Author: Kang David W. Tannenbaum Renee
- Genre: Medicine // Pharmacology
- Year: 2022
- Publisher: S. Karger Publishing
- City: Oxford
- Language: English
- pdf
‘ENHANZE® drug delivery technology: Advancing subcutaneous drug delivery using recombinant human hyaluronidase PH20’ provides readers with in-depth information on the potential benefits and challenges of subcutaneous (SC) drug delivery, the biology of hyaluronan and hyaluronidases in the SC space, and a comprehensive overview on the history of hyaluronidases and the development of recombinant human hyaluronidase PH20 (rHuPH20). Current applications of rHuPH20 as well as approved biotherapeutics utilizing HuPH20-facilitated SC drug delivery are summarized, and the underlying non-clinical and clinical development approaches are introduced as a basis for future application to biologics in various disease areas.
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