Ebook: Neurodegeneration and Alzheimer's disease: the role of diabetes, genetics, hormones, and lifestyle

Currently, the human population is on a collision course for a social and economic burden. As a consequence of changing demographics and an increase in human individuals over the age of 60, age-related neurodegenerative disorders are likely to become more prevalent. It is therefore essential to increase our understanding of such neurodegenerative disorders in order to be more pro-active in managing these diseases processes. The focus of this book is to provide a snapshot of recent advancements in the understanding of basic biological processes that modulate the onset and progression of neurodegenerative processes. This is tackled at the molecular, cellular and whole organism level. We hope that some of the recent discoveries outlined in this book will help to better define the basic biological mechanisms behind neurodegenerative processes and, in the long term, help in the development of novel therapeutic approaches.;Current Understanding of Alzheimer's Disease and Other Neurodegenerative Diseases, and the Potential Role of Diet and Lifestyle in Reducing the Risks of Alzheimer's Disease and Cognitive Decline / Charles S Brennan, Margaret A Brennan, WMAD Binosha Fernando, Ralph N Martins -- Alzheimer's Disease and Other Neurodegenerative Diseases / Stephanie J Fuller, Hamid R Sohrabi, Kathryn G Goozee, Anoop Sankaranarayanan, Ralph N Martins -- Current and Developing Methods for Diagnosing Alzheimer's Disease / Stephanie J Fuller, Nicholas Carrigan, Hamid R Sohrabi, Ralph N Martins -- The Link Between Diabetes, Glucose Control, and Alzheimer's Disease and Neurodegenerative Diseases / Giuseppe Verdile, Paul E Fraser, Ralph N Martins -- Diet and Nutrition, and their Influence on Alzheimer's Disease and other Neurodegenerative Diseases / Stephanie R Rainey-Smith, Rhona Creegan, Stephanie J Fuller, Michele L Callisaya, Velandai Srikanth -- Carbohydrate and Protein Metabolism: Influences on Cognition and Alzheimer's Disease / WMAD Binosha Fernando, Veer B Gupta, Vijay Jayasena, Charles S Brennan, Ralph N Martins -- Fat and Lipid Metabolism and the Involvement of Apolipoprotein E in Alzheimer's Disease / Eugene Hone, Florence Lim, Ian J Martins -- Inflammation in Alzheimer's Disease, and Prevention with Antioxidants and Phenolic Compounds -- What Are the Most Promising Candidates? / Matthew J Sharman, Giuseppe Verdile, Shanmugam Kirubakaran, Gerald Münch -- Cognitive Impairments in Alzheimer's Disease and Other Neurodegenerative Diseases / Hamid R Sohrabi, Michael Weinborn -- Animal Models of Alzheimer's Disease / Prashant Bharadwaj -- The Products of Fermentation and Their Effects on Metabolism, Alzheimer's Disease, and Other Neurodegenerative Diseases: Role of Short-Chain Fatty Acids (SCFA) / WMAD Binosha Fernando, Charles S Brennan, Ralph N Martins -- Hormonal Expression Associated with Alzheimer's Disease and Neurodegenerative Diseases / Giuseppe Verdile, Anna M Barron, Ralph N Martins -- The Link Between Exercise and Mediation of Alzheimer's Disease and Neurodegenerative Diseases / Belinda Brown, Tejal M Shah -- Current and Prospective Treatments for Alzheimer's Disease (and Other Neurodegenerative Diseases) / Steve Pedrini, Mike Morici, Ralph N Martins -- The Role of Genetics in Alzheimer's Disease and Parkinson's Disease / Tenielle Porter, Aleksandra K Gozt, Francis L Mastaglia, Simon M Laws -- Final Thoughts Regarding Alzheimer's Disease, Diet, and Health.