Ebook: Bioanalysis of pharmaceuticals: sample preparation, separation techniques, and mass spectrometry

Introduction -- Physicochemical properties of drug substances -- Biological samples: their composition and properties and their collection and storage -- General chromatographic theory and principles -- Quantitative and qualitative chromatographic analysis -- Sample preparation -- Liquid chromatography (HPLC) and liquid chromatography-mass spectrometry (LC-MS) -- Gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) -- Analysis of small molecule drugs in biological fluids -- Analysis of biopharmaceuticals in biological fluids -- Regulated bioanalysis and guidelines.;Bioanalysis of Pharmaceuticals: Sample Preparation, Separation Techniques and Mass Spectrometry Editors Steen Honoré Hansen Department of Pharmacy, Faculty of Health and Medical Sciences, Copenhagen University, Denmark Stig Pedersen-Bjergaard School of Pharmacy, University of Oslo, Norway and Department of Pharmacy, Faculty of Health and Medical Sciences, Copenhagen University, Denmark Bioanalysis of Pharmaceuticals: Sample Preparation, Separation Techniques and Mass Spectrometry is the first student textbook on the separation science and mass spectrometry of pharmaceuticals present in biologi.