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This book constitutes the proceedings of the 22nd Annual Conference on Research in Computational Molecular Biology, RECOMB 2018, held in Paris, France, in April 2018.
The 16 extended and 22 short abstracts presented were carefully reviewed and selected from 193 submissions. The short abstracts are included in the back matter of the volume. They report on original research in all areas of computational molecular biology and bioinformatics.

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