Ebook: Microarrays: Preparation, Microfluidics, Detection Methods, and Biological Applications
Author: Leming Shi Roger G. Perkins Weida Tong (auth.) Kilian Dill Robin Hui Liu Piotr Grodzinski (eds.)
- Genre: Biology // Molecular
- Tags: Analytical Chemistry, Biotechnology, Biochemical Engineering, Electrochemistry, Industrial Chemistry/Chemical Engineering, Characterization and Evaluation of Materials
- Series: Integrated Analytical Systems
- Year: 2009
- Publisher: Springer-Verlag New York
- Edition: 1
- Language: English
- pdf
The area of microarrays has evolved from genomics, and has been applied to proteomics and single cell studies as well. The applications of microarrays benefit diverse fields ranging from fundamental systems biology to practical diagnostic tests. This book provides a critical analysis of the applications of microarrays in several key areas of bioanalytical research including DNA studies, peptide arrays, protein arrays, combinatorial chemistry arrays, cell-based arrays, and glycoarrays. Further progress in microarrays is being spurred by the advances in micro- and nano-fabrication technologies, modern molecular biology, and data mining. This book is designed to be a useful source of fundamental and current information for microarray research practitioners and for those who are just entering this field.
Combinatorial chemistry is used to find materials that form sensor microarrays. This book discusses the fundamentals, and then proceeds to the many applications of microarrays, from measuring gene expression (DNA microarrays) to protein-protein interactions, peptide chemistry, carbodhydrate chemistry, electrochemical detection, and microfluidics.