Ebook: Membrane Protein Crystallization

Academic Press is an imprint of Elsevier, 2009. - 308 p. ISBN: 0123749875This volume of Current Topics in Membranes focuses on Membrane Protein Crystallization, beginning with a review of past successes and general trends, then further discussing challenges of mebranes protein crystallization, cell free production of membrane proteins and novel lipids for membrane protein crystallization.
This publication also includes tools to enchance membrane protein crystallization, technique advancements, and crystallization strategies used for photosystem I and its complexes, establishing Membrane Protein Crystallization as a needed, practical reference for researchers.The purpose of this book is to familiarize the membrane biologist with the general theory and experimental approaches for membrane protein crystallization. The book begins with a comprehensive explanation of general theory and experimental approaches of crystallization followed by a detailed description of two of the more recent and successful membrane protein expression systems (eukaryotic cell‐free expression and a novel photosynthetic bacterial expression system). Traditional expression systems for both prokaryotic and eukaryotic membrane proteins are summarized in subsequent chapters that address a variety of membrane protein crystallization techniques. Structural themes and biological implications resulting from X‐ray crystallographic structures for specific membrane protein classes are also reviewed.