Ebook: Glioblastoma: Molecular Mechanisms of Pathogenesis and Current Therapeutic Strategies

Glioblastoma, the deadliest of all primary brain tumors, is heterogenic and has very complex pathology and multiple mechanisms of cell proliferation and growth. This book describes all the latest concepts about the molecular mechanisms of pathogenesis of glioblastoma and new therapeutic opportunities. The contributors to this book include basic scientists and clinicians, who are experts in the field, and dedicated investigators in finding novel strategies for treatment of glioblastoma. It is important for us to know the strategies we have accumulated so far for the management of this malignancy so that we can make further attempts to explore unknown avenues to combat it completely in the near future.

Glioblastoma is the most malignant brain tumor that still remains incurable. It is such a deadly disease that patients do not survive more than a few months after diagnosis. Our understanding of the histopathology and molecular mechanisms of formation of glioblastoma is rapidly advancing so as to provide us clues for devising rational therapeutic strategies for treatment of this malignancy. It is important that we continue to improve our knowledge about the pathogenesis of this devastating disease and explore new areas to find successful therapeutic strategies.

Various approaches such as sophisticated imaging techniques, improved surgical procedures, ground-breaking strategies for radiotherapy, chemotherapy, immunotherapy, chemoimmunotherapy, and photodynamic therapy are being used for eradicating glioblastoma. Hopefully, this book will be an important source of information on glioblastoma and therefore be highly useful to the students, postdoctoral fellows, principal investigators, and clinicians involved in this field.