Ebook: Bioinformatics

InTeOp – 2012, 335 pages
ISBN: 9535108788, 9789535108788The book introduces the basic concepts and then explains its application to problems of great relevance, so both novice and expert readers can benefit from the information and research works presented here.This book is divided into different research areas relevant in Bioinformatics such as biological networks, next generation sequencing, high performance computing, molecular modeling, structural bioinformatics, molecular modeling and intelligent data analysis.Contents:
Preface
Section 1 Analysis of Biological Networks
Hierarchical Biological Pathway Data Integration and Mining
Investigation on Nuclear Transport of Trypanosoma brucei: An in silico Approach
Systemic Approach to the Genome Integration Process of Human Lentivirus
Section 2 Sequence Analysis
SeqAnt 2012: Recent Developments in Next-Generation Sequencing Annotation
Section 3 High-Performance Computing
Towards a Hybrid Federated Cloud Platform to Efficiently Execute BioinformaticsWorkflows
Hardware Accelerated Molecular Docking: A Survey
Section 4 Molecular Modeling
Incorporating Molecular Dynamics Simulations into Rational Drug Design: A Case Study on Influenza a Neuraminidases
Using Molecular Modelling to Study Interactions Between Molecules with Biological Activity
Section 5 Structural Bioinformatics
On the Assessment of Structural Protein Models with ROSETTA-Design and HMMer: Value, Potential and Limitations
Section 6 Intelligent Data Analysis
Bacterial Promoter Features Description and Their Application on E. coli in silico Prediction and Recognition Approaches
Computational Approaches for Designing Efficient and Specific siRNAs
Novel microRNA Cloning Using Bioinformatics
Ensemble Clustering for Biological Datasets
Research on Pattern Matching with Wildcards and Length Constraints: Methods and Completeness