Ebook: Nonhuman Primates I

The International Life Sciences Institute (ILSI) was estab­ lished in 1978 to stimulate and support scientific research and educational programs related to nutrition, toxicology, and food safety, and to encourage cooperation in these programs among scientists in universities, industry, and government agencies to assist in the resolution of health and safety issues. To supplement and enhance these efforts, ILSI has made a major commitment to supporting programs to harmonize toxicologic testing, to advance a more uniform interpreta­ tion of bioassay results worldwide, to promote a common understanding of lesion classifications, and to encourage wide discussion of these topics among scientists. The Mo­ nographs on the Pathology of Laboratory Animals are de­ signed to facilitate communication among those involved in the safety testing of foods, drugs, and chemicals. The complete set will cover all organ systems and is intended for use by pathologists, toxicologists, and others con­ cerned with evaluating toxicity and carcinogenicity stu­ dies. The international nature of the project - as reflected in the composition of the editorial board and the diversity of the authors and editors -strengthens our expectations that understanding and cooperation will be improved worldwide through the series. Alex Malaspina President International Life Sciences Institute Preface This book, on Nonhuman Primates, is the eleventh volume of a set pre­ pared under the sponsorship of the International Life Sciences Institute (ILSI).

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This volume is one of a set of concise, well illustrated and authoritative studies of natural and experimental lesions of laboratory animals arranged by organ system. Volumes 11 and 12 the latest in a set of twelve are devotedto pathologic lesions in nonhuman primates. The first volume includes data on diseases which affect two or more anatomic systems. The second is arranged by anatomic systems. Precise differential diagnostic criteria and terminology are given emphasis. Included are useful data on pathogenesis, etiology, biologic behavior, frequency in different species under varying laboratory conditions. The significance of each lesion is considered and comparisons are made with other species including man.References to the world literature have been selected to permit access to the critically important publications of each subject.